2 g. Leucorrhoea commenced on 2nd day, and continued till 7th, scanty and acrid at first, then bland and copious. (This was observed during both provings.) Catamenia appeared in due time, but ceased after 12 hours, which is altogether unusual.
2 h. Appetite diminished as the drug illness became more pronounced; thirst was increased; tongue was broad, furred in middle, and reddened at tip and sides. (Ibid.).
Provings
1. If a small piece of the root be chewed, or a few dr. of tinct. be applied to tongue, it produces sense of faintness and exhaustion. On one occasion, after filtering some of the tinct., eyelids became somewhat inflamed, with smarting, itching, and prickling pains, r. more than l. On bathing face with a lotion of a few dr. of tinct. to Oj of water, a creeping, smarting, and itching sensation was felt in cheeks and lips. (Ibid.)2. A gentleman chewed a piece of root for experiment, and was immediately seized with nausea, vomiting, spasms, general convulsions, and fainting fits, which terminated in death after 3 hours (Ibid.)
3. A young lady ate a large root by mistake. Soon after she was seized with violent vomiting, spasms, swoonings and convulsions. The speedy discharge of the poison by vomiting enabled her to resist the toxic influence and regain her usual health in a few day (Ibid.)
4. The odour of the root has ben known to produce such an effect on the system as to confine the subjects of its influence to bed for days. In these instances nausea, faintness and lassitude were the symptoms observed. (Ibid.).
Observations in animals
1. An ox, after having eaten the top of the plant early in the spring, vomited and staggered about as if intoxicated. It continued reeling and staggering for 3 day, and then recovered. (Ibid.)