1 d. Jan 8th, 6:15, ate one seed. Scraping when chewing it, especially in throat.645 a. m., warm feeling in stomach empty eructation. Head dazed, giddy. Much rumbling in bowels. Bruised feeling sinks from knees into legs, and becomes fixed in ankle – joints. heat in occiput. Pain through dorsal muscles; pressing in left calf. Heat in stomach increases. Anxious feeling in scrob cordis. Pressing pain in left ankle – joint Heat in occiput. Pain through dorsal muscles; pressing in left calf. Heat in stomach increase. Anxious feeling in scrob cordis. pressing pain in left ankle – joint, upper arm, hypochonder and inguinal region. 7 a. m., constant crawling in left big toe. Empty eructation, discharge of flatus; frequent stitches behind cartilages of 6th and 7th. ribs. Bubbling of fluid deep in abdomen and rumbling of flatulence. Calves stiff when walking; constant urging to urinate; drawing in back of left hand; pressure in left pectoral muscles affecting breath; shooting in lumbar muscles. 7:45 a. m. belly moderately distended, soft, painful on pressure deep in umbilical region. Pressive pain in right knee and left calf on walking; abdomen tympanitic; persistent feeling of warmth in stomach; frequent eructation of air; scrapy feeling in inner aspect of left tibia. Chilliness proceeding from lumbar vertebrae. Much borborygmus; violent pains in umbilical region extending to left hypochonder and left side of thorax painful jerks from navel to lumbar region. Urging to urinate. Persistent dryness and scraping in throat 8:30 a. m., pain and distension of abdomen and urging to urinate continue. 9 a. m., soft stool; until 1 p. m. more urine than usual passed – 10th. 6:45 am., took 1 seed. Whilst chewing this scraping in throat, which increases later. 7:45 a. m., heat and confusion in occiput formication in toes, pressing in muscles of l leg, especially lower part of calf; pressure in forehead, burning hot ears, pulse 6 or 7 beats slower, soft; confusion of head and pressure in temples and muscles of right upper arm. 9:30 a. m., stiffness in nuchal muscles, pulse 65, pressure in left shoulder – join; urging to urinate qualmish feeling in scrob cordis; noise deep in abdomen; drawing in dorsum of right foot; increase of saliva; pressing pain in frontal muscles hot feeling in stomach, and spasm rising up to oesophagus; pressive pain in right ankle – joint and right pectoral muscles; much borborygmus and pain in umbilical region. – 12, noon, ate 2 more seeds. Scraping while chewing and afterwards. 12:30 p. m., pressing in left calf, right knee, right wrist; increased saliva; nausea; pressure on left frontal and temporal muscles, worst. when sitting; formication under skin of both legs and feet; pressure in forehead. 1 p. m., black points before eyes, great heat and weight in head; persistent nausea and salivation; stitches in urethra; heat in stomach; tearing in left toes and dorsum of left foot; nausea, inclination to vomit. 2 p. m., pulse slow, full soft; great exhaustion and heaviness of head; protrusion in left. inguinal ring on coughing after some milk food nausea, heaviness and pressure in forehead, weariness and much chilliness in lumbar vertebrae. 2:45 p. m., stitches in rectum; head confused, unable to think; pains in muscles of lower extremities continue; pulse 87, large, full bounding; much chilliness, cold finger – tips; frequent urging to urinate, with stitches in urethra; when walking in room, some heart’s beats which shake the chest; nausea now and then. 4 p. m., painful pressing and stitches in neck of bladder, frequently; much yawning with nausea, much eructation with persistent heat and confusion of head; bubbling of fluid abdomen; with the attacks of nausea there always were spasms in neck of bladder, with drawing pain and urging to urinate, every attack of bladder spasm commences with a twisting pain round navel, which then extends down to neck of bladder. Before and after these much bubbling of fluid in abdomen and acid eructations; better in open air During all the time and on the m. of the 11th scraping in throat and painful chapped lips. Stool on 11th delayed, scanty and hard. ( A.h. Z., xxxiv, 278.)
2. a Dr. HERING took 4 small doses of 2nd trit. of seeds. First headache externally on forehead and right zygoma for a few h. The usual stool, followed by a hard stool, then a 3rd stool, soft, and a 4th with nausea and great flow of saliva, later a 5th stool. A slight catarrh with cough was increased; the throat felt swollen; the following n. hollow cough. Subsequent effects; Soft hemorrhoidal swelling; increased itching of nose when eating; much excitement from trifling cause; nocturnal attacks of anxiety causing constriction of chest, could not get to sleep before m. During sleep perspiration and constant dreaming. Can with difficulty be roused from m. and noon sleep, moved about with an effort which did him good.
2 b. After triturating J., sudden attacks of coryza, with sneezing, frequent discharge of mucus which soon becomes yellow alternating with white discharge, and lasts long; with occasional coughs, with difficult expectoration in the intervals frequent easy hawking up of lumps of mucus; at same time transient pains here and there in head. Short cough 1st day, worse 2nd d. Attacks of anxiety constricting chest, preventing sleep, n. Violent cramps and twitchings, the calves turned round to the shins. Without feeling cold or hot declares he has fever and must sleep, 1st d. Wine acts more strongly. Putting the hands in cold water relieves the symptoms immediately. Dryness in throat with thirst, but he dreads drinking on account of the nausea, after some hours vomiting of food and a short hacking cough. (Amerik, Arzneipr., 585.)
3. a. Dr. HUMPHREYS took 1 dr. 1st dil Confusion and stupid feeling in head for 2 d. Nausea and burning in stomach for some hours, after 1/2 h. Acute colic in transverse colon and borborygmus. Call to stool after 1/2 h. Restless n. from flow of thought and palpitation of heart; dry mouth all n.
3 b. Too 5 dr. 2nd dil. Confused and stupid in head, 2nd d. After some m. headache, pressing in at temples to crown, for 1/2 hours, goes off in open air, 2nd or 3rd d. Itching of eyelids for several d. Pain in right ear for 1/4 h. Pale face with dark rings under eyes, 2nd d. Soreness in left angle of mouth. Extreme dry feeling in mouth, followed by actual dryness of mouth and tongue with out thirst all n. from 2nd to 3rd day; then as if mouth were scalded to 6th day; always worse at n. Thirst, evening 4th day. Constant eructation of air for 28 h. Pain and uneasiness in abdomen, sinking feeling in stomach as during severe diarrhoea, all a. m., 3rd d. Feeling of sinking and nausea in praecordia, afterwards a soft stool, 2nd d. All a. m. pain around navel. Some bellyache and feeling as if diarrhoea were coming, m. 2nd d. Borborygmus and rumbling in bowels all n., the same all day, relieved by walking in open air, returns in warm room; 2nd day Soft stool for several day, thereafter costiveness, with slight headache, pressing in at temples, 6th d. Stool at n., very unusual. Copious evacuation of urine clear as water. Perceptible increase of urinary secretion after exertion, evening 4th day. Pain in right testicle and scanty urine, 4th d. Pain in genitals as after excessive coitus all 6th day. Drawing pain in genitals along inner side of right thigh to knee, 6th d. Strong heart’s beats for several day, throbbing pain in left clavicle, m. 3rd d. Pain and numb feeling from elbow to tips of 4th and 5th fingers, with burning causing insensibility, after 1/2 hours; lasts 1/2 hours, and is repeated after 4 day along ulnar nerve. Violent itching, as from scabies, between thumb and index, increased by rubbing. Violent itching in the commissures between 1st and 2nd finger, relieved by rubbing, m. 3rd d. Pain in both houghs, for several d. Restless tossing about and beating of pulse, all n. After lying down, sleepless for several hours with beating of pulse, 3rd. d.
3 c. Took 3 dr. and dil. Pain in temples, in – pressing and throbbing, extending sometimes to crown, lasting all day, worse in room, aft. 1 h. Itching and soreness of edges of eyelids, relieved by rubbing, aft. 1 h. Pain in left, extending gradually to right zygoma, ending in pain in right ear, 2nd d. Two hard painless pimples on middle of right check which go off gradually. Itching and tension around mouth, relieved by rubbing, aft. 1 h. Itching and tension in lips 2nd day, ulceration, soreness and tension in right angle of mouth, 4th d. Dry mouth without thirst after 1 hours, then feeling as if mouth was scalded all n. and m. of 3rd d. Burning in gullet. Eructation all 1st d. Sinking feeling in scrob. cordis and slight nausea, immediately. Pain in hypogastrium and call to stool. Pain around naval with rumbling, discharge of flatus and call to stool, m. 2nd d. Pain in left testicle 3rd d. Strong heartbeats, aft. 1 h. Violent pain in left clavicle, a. m. 3rd d. Pain along left ulnar nerve, after 1 h. Several small red papules on wrist and back of right hand, 2nd day, go off in a few d. Pain in first joint of right thumb extending to wrist, m. 2nd d. Violent pain in first phalanx of right index extending to its tip after 5 h. Itching between right index and middle finger and on outer side of palm, after 7 h. Sore pimple in bend of right thigh, 2nd d. Painful tearing in left knee and ankle, after 7 h. Violent rheumatic pain in left ankle – joint, 3rd d. Rheumatic pains in ball of right foot, m. 4th d. Itching between toes, n. 1st day (Ibid.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.