16d. 4th proving: 1st Dec., m., 6 grs. of a trituration of equal parts of agar. and milk sugar. In 1.1/2 hours nausea and accelerated respiration, followed by feeling of uneasiness in belly, with sensation in anus as if diarrhoea were about to ensue. Noon, 15 grs. After dinner, great heat and redness of face, unusual symptoms. 6 p.m. Sudden call to stool, which soon goes off. Great salivary secretion. When walking, such weakness of knees that they bent beneath him, at same time feeling of general illness, nausea, sad disposition. – 2nd. No stool yesterday – most unusual; slept well, coughing up of clear lumps of mucus. M., 5 grs. Hard stool passed with effort in the evening 15 grs. at bedtime. – 3rd. No med. No symptoms. – 4th, m., 20 grs. Slight, transient, tearing drawing in right knee-joint. Noon, violent, long-continued prick like a needle continually pressed in at one spot just above the left eyebrow. The pain was removed by violent scratching. At same time, but lasting longer, fine-tearing pain in left elbow-joint, changing into pricking itching, relieved by scratching. Drawing pains spreading from the interstice between left thumb and index to these fingers. Dull pain in left temple, and at the same time tearing pain in left lower costal region anteriorly. Acute drawing tearing in posterior side of left forearm, and at same time above elbow- joint in upper arm. All these sensations transient. Repeated itching pricking pain above right eyebrow, going off by scratching. Needle-pricks at left side of forehead. Burning heat and redness of face. Tearing slight pain on right side of top of head. Painfulness of left eyeball. Pain in left lower costal region. Painful tearing in right knee-joint. Much itching here and there on hairy scalp. Urinary secretion diminished. Itching pricking above left eyebrow and left ear, on head, and various other parts. Quivering of left lower eyelid. – 5th. No med. From early m., intimations of the hip and sacral pain, – the latter on left side, resembling lumbago. Itching in various parts, needle- pricks here and there. Much yawning without weariness, evening – 6th, m., 30 grs. after breakfast. Very acute, sudden, pressive tearing pain in right eyeball, not affecting sight. Painful pressure on left eyeball, superiorly and externally. Violent paralytic, transient dislocation pain in tendons of dorsal side of left wrist, as from mechanical injury. Acute pressive pain in small spot in left temple. Sore pain in centre of left thorax as after a blow, not affecting breathing. Pressive pain in right eyeball superiorly and externally, momentary, but frequently recurring. Afternoon, the pain in chest became very violent, and a similar pain came in right side affecting the breath; it went off suddenly after lasting 2 1/2 hours, and then there came on the pain above left eyebrow, which quickly went off, and was followed by discomfort in upper part of abdomen with feeling of nausea there and trembling of knees, which soon went off. E., great itching under left eyelid, as if in eyeball. During the whole proving frequent discharge of inodorous flatus after distended feeling in rectum. Forcible expiration without cough brought away a great quantity of transparent lumps of mucus, with great relief to chest. – 7th. The dull hip pain in the region of the left os ilii very violent, lasted all afternoon, very tiresome when sitting, but going of completely when walking. Much flatus discharged, preceded by colicky pain. A soft, very copious stool. – 8th. The pain in left hip felt in the m. A great quantity of the gelatinous or starch-like expectoration for several day past. – 9th. Still traces of the hip pain. Pain in right side of chest, tearing on posterior aspect of forearm. (Ibid.)
17. SAMUEL MAX, medical student, aet. 20, strong constitution, sanguine temperament, in good health. 21st Oct., m., 5 drops tinct. agar. in water. In a few m., heaviness in feet and head, very transient. – 22nd, 10 drops, some confusion of head, heaviness and coldness of extremities, quivering of left upper eyelid, repeated at noon. – 23rd, 15 drops, confusion of head and quivering of upper eyelid. – 31st, 5 drops. Soon confusion of head and coldness of lower extremities. All right after breakfast. – 4th Nov., 10 drops. In 10 m., coldness of lower extremities. Heaviness of head and inclination to vomit, with watery eructations. – 9th, 10 drops. Soon coldness in lower limbs and inclination to vomit. Transient headache. (Ibid.)
18. Dr. ROSENBERG, aet. 38, sanguine choleric temperament, robust constitution, and, though corpulent, irritable. Disposition to lumbago, sore throat, and fever. At present quite well. – 1st March, 7 a.m., 10 drops tinct. Immediately, burning and scraping in throat, extending deep down into left side of chest. 9 a.m., these symptoms went off. and he took his breakfast. 1:30 p.m., when walking in open air, suddenly such a violent pain in the sacrum that he could not take another step; at same time vertiginous nausea, the knees shook, he had to drive home in a cab. Here he vomited his breakfast, which removed the nausea, but the pain in the sacrum not only continued as violent, but extended the whole length of the spine th the nape. The spine was painful to the touch in several spots. E., alternation of chill and heat, restless sleep at n., many unconnected dreams, next m. quite prostrated and weak. – 2nd. Pain in sacrum and back still violent, so that he could not leave his bed; frequent palpitation of heart, little appetite, no stool, copious secretion of urine of pale yellow colour. E., some chilliness followed by heat. Sleep much disturbed. – 3rd. Sacral pain better, dorsal pain still very violent on the slightest movement. E., pain in splenic region, rumbling in bowels, followed by a stool with effort. N., better, no fever. – 4th to 7th. Went about his work, but any considerable movement caused violent pain in some spots of the spine. Spirits very depressed. Appetite bad, stool irregular, animal food caused heartburn; at n. he was troubled by flatulence and a deep contractive pain in splenic region. – 19th, 5:30 a.m., 5 drops tinct. He lay in bed 1.1/2 hours reading, but could not pay attention to what he read; he became irritable, was cross with his servant, and disposed to scold. A meeting he attended later excited him still more; he got such violent palpitation he had to go and lie down. He soon fell asleep, dreamt much, and on waking was bathed in sweat, and trembled. Later excessive hunger, but his food was not relished; this irritated him; he again got palpitation and convulsive cough with anxious sweat, and was so low spirited that he could not bring himself to speak to anyone, and locked himself up in his room. Evening, quiet, ate a little and enjoyed reading the newspaper. Midnight, awakened by a spasmodic pain in left side of abdomen, with call to stool, but on making an effort to evacuate there came a violent pain in sacrum that extended down into lower extremities. The lower limbs felt bruised and semi-paralysed. The call to stool combined with a sort of tenesmus lasted till m., when violent shooting, burning pains low down in the spine came on. – 20th. The dorsal and sacral pain lasted all day so violently that he had to keep his bed, and lie quite still. E., the sacral pains were nearly gone, but the lower extremities were very painful, as though they had been bruised by a heavy weight. – 21st to 23rd. So much better that he could walk out, though not free from pain; the lower extremities were most painful when he got up after sitting some time. – 2nd April, 10:30 p.m., 12 drops of 1x dil. Soon fell asleep, but woke at 3 am. with pressive headache; yawned much, and every time he did so had an involuntary fit of laughter. These symptoms lasted about an hour and were followed by profound sleep, from which he woke at 6 a.m., and had convulsive cough, trembling of heart and anxiety. Next m. could go out, but his spirits were very bad. During the day, frequent yawning. E., drawing in back and sacrum. N., three watery stools, with pain in spleen. – 3rd and 4th. The same symptoms, though slighter. The dorsal and sacral pain lasted a fortnight longer. (Ibid.)
19. RUDOLF SCHMIDT, medical student, began to prove on 15th Oct., with 6 drops tinct., increased the dose gradually till 28th, when he took 45 drops, but experienced no effects. – 29th, 50 drops. In 6 hours a tiresome feeling of tension externally in the region of the thyroid gland, increased in evening 10 p.m., a similar tensive sensation in right groin, increased by rotating outwards and extending right thigh. This sensation continued on 30th, but went off on walking, returning when standing, and also slightly when sitting or lying. It increased towards evening amounting then to slight pain, the tension in thyroid remained always the same. – 31st. Pain in groin less when walking, worse when sitting, lying or standing. Increased in evening – 1st Nov. The tension lasted all day, and interfered with walking; he could only walk slowly. – 2nd to 4th. The pain as before in the groin; it is aggravated by touch. – 5th. Pain much relieved, not felt when walking, and the tension only felt when standing, sitting, or lying. Tension in thyroid gland gone by the 8th. – 9th, 50 drops. After 8 hours the tension in groin returned under same conditions as before. It lasted till 11th, returned for instants on 13th; by 15th was quite gone. (Ibid.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.