11b. 15th Nov. Began another series of provings with tincture prepared with fresh fungi. At 11 a.m. 1 drop in water. In 5 m. sudden vertigo, as though he would fall: it lasted only 5 seconds, and was followed by electric pricks in right knee. After dinner, before the siesta, roaring in left ear, frequent muscular twitching in left natis and a convulsive shock in left shoulder. The sleep was unusually long and profound. After sleep a chilly feeling all over body, especially in both feet. 4 p.m., smarting pricking in roots of ciliae of left upper eyelid. E., prostration and weariness. 9 p.m., in bed, undulating muscular jerking in left forearm, then in left thigh. After 1 hour heat spread gradually all over the body, until it became intense; the lower extremities burned to such a degree that he must often throw the clothes off them. The blood seemed to flow quite hot through the vessels, the circulation was feverishly excited, the pulse strong, hard and quick. 11 p.m., burning thirst. Accompanying these febrile symptoms were: cutting sore pain in upper part of left nostril, felt at every inspiration, but not during nasal expiration, at same time stuffed and coryza feeling, with discharge of watery fluid from both nostrils, frequent sneezing and yawning, frequent slight hawking up of small masses of mucus from fauces and posterior nares, constant roaring in left ear with creaking in both ears during empty swallowing, acrid, smarting taste on left half of tongue, sore pain in tip of tongue, which seemed to be occupied by a vesicle, a not disagreeable burning cooling sensation from fauces through oesophagus to stomach as from peppermint or horse-radish, electric pricks in skin of anterior aspect of right thigh, and violent convulsive shock of left shoulder. This febrile excitement lasted till midnight, after which the heat gradually subsided, and he slept and dreamt much that was not remembered. The urine passed at night was clear, sherry-coloured, and of normal quantity. Morning, a transient, rather severe, shooting deep in right hypochondrium, coryza gone. – 16th. All forenoon, confused head, boiling roaring in left ear. Exhaustion of body, white furred tongue, slimy, sticky, taste. Afternoon pretty well. 6 p.m., 2 drops. Soon transient stupefaction of head. N. good. M. in bed, painful tension and pressure in left hip and lumbar region, but only when lying on that side, going off when lying on right side. Twitching jerking in hairy scalp above left ear, close to concha, and sometimes in concha itself, muscular jerking on left side of nape, 1. side of neck, 1. forearm, near joint of elbow, with violent electric shock of lower jaw coming up from a lumbar vertebra. – 17th, 9 a.m., 3 drops. Forenoon, stupefaction of head. Afternoon, when inspiring air by left nostril a painful feeling high up, as if the mucous membrane were excoriated there. 6 p.m. In all left side of head, constant dull pain, which after 1 hour increased to violent digging, at same time roaring in left ear, rumbling in left side of abdominal cavity, flatulent distension of abdomen, slight griping between navel and right hypochonder, discharge of much flatus smelling of tinct. of agar.; prostration and weakness. In spite of the headache, fell asleep, but woke about midnight with violent digging pain in left temple, relieved by pressure of hand, recurring when pressure was removed. After a while headache went off and he fell asleep. On waking at 5 a.m. itching in 1 meatus and ext, with a prick in interior of ear as with an icy-cold needle; pricking pains in dorsal vertebrae, right heel, toes of both feet, as from splinters stuck in; muscular twitching close to left ear, 1. elbow, 1 intercostal muscles, both glutei, and pectoralis, with jerking shocks coming in impulses, now in 1 hip now in r hand, proceeding from the corresponding joint After getting up felt well all except bruised feeling in nape and occiput. – 18th, 8 am, 4 drops. Forenoon, confused head, smarting erosion on 1 side of hairy scalp, smarting pricks on border of r upper eyelid, bruised feeling in right occiput, great sensitiveness to cold, especially in hands and feet, with pale, ill-looking countenance. After dinner frequent twitching clapping or fluttering in tympanic cavity of right ear. Jerking of tensor tympani, and twitching in left abdominal muscles, and the well-known pricking as from splinters pushed in, now left meatus auditory. ext., left cheek, right upper lip, point of chin, now in dorsal vertebrae, left pectoralis muscle near nipple, navel and various part of skin; at same time a pressive pain in right side of fauces. Simultaneously or alternately with them sometimes there was frequent muscular jumping in ears, temple, face, upper lip, throat, chest, sacro-lumbar region, abdominal walls, extremities, with jerking movement of one or other thumb and single fingers N good. M, after waking, aching tensive pain in tendons of left upper arm, near bend of elbow, lasting several m. – 19th, 8 a.m., 10 drops. Noon, confusion of head, after dinner a short intimation of a dull digging pain in left temple, with the familiar cold feeling in right natis. E., before going to bed, erosive itching in hairy scalp of occiput causing him to scratch, with frequent involuntary jerking of muscles of lower jaw. E., in bed, cramp-like pain in muscles of left upper arm below deltoid, lasting some m., thereafter a similar pain from os ilii downwards towards the muscles of anterior aspect of right thigh, with painful twitching pricks in anterior of left ear, at same time restlessness and considerable trembling of muscles of left upper arm and thigh, with slight jerky shocks of those limbs, and frequent muscular jumping in various parts. N. good M., after waking, a sore shooting pain in inner canthus and beneath upper lid of right eye, with a short cramp-like pain in the muscles of the anterior aspect of right thigh, and a pricking pain as from splinters stuck in right heel and toes. – 20th, 8 a.m., 12 drops. Forenoon, transient pressive pain in left forehead with eroding smarting now and again in skin. After dinner restlessness in lower jaw and lips, with fine trembling movement and frequent twitching on and in right concha, and twitching jerks in interior or right ear. 8 p.m. A sudden lightning-like pricking in right cheek, at exit of infra-orbital nerve, close to orbital border, as from sharp splinters; immediately afterwards a convulsive shock of the lower jaw, making him bite his tongue. N. good. M., after waking eroding prick in hairy scalp of left parietal region, and transient pricking as from splinters in right temporal region near eye, followed by muscular jumping in various parts. Both inner canthi sealed up with mucus. – 21st, 8 a.m., 15 drops. Soon a sore pricking pain in left inner canthus. Forenoon, when walking in open air a digging pain from left forehead along parietal region through the whole cerebral hemisphere to the occiput, followed by pressive sensation in crown, with constant accumulation of water in mouth, causing him to spit frequently. After dinner, frequent twitching shooting deep in left side of cerebrum, and frequent pricks as from splinters stuck in, sometimes in right pectoral muscle, in right true and false ribs, sometimes in left index. E., in bed, sudden violent pricking as from splinters in left cheek near eye, lasting some seconds; thereafter similar pains in left side of back, beneath scapula, in left hypogastrium and right toes, with frequent muscular jumping in various parts. N. good. M., in bed, pressive digging pain in right half of occiput, with simultaneous splinter-pricks in middle of right cheek and lowest ribs, with frequent twitching of various muscles. – 22nd, 9 a.m., 20 drops. Forenoon, bruised pain in left nape and shoulder, and transient pressive pain in tendons of left upper arm near bend of elbow, lasting some m. After dinner cold feeling in point of right elbow, as if it had on it a piece of ice; at same time the familiar cold feeling in parts of both nates, and an icy coldness of both feet up to ankles, especially in big toes. All this in the room. 5 p.m. On raising left arm a violent dislocation pain in left deltoid, on attempting to raise arm felt as if thousands of splinters were in the muscle. This lasted 10 m. Afterwards splinter-pricks in right intercostal muscles below nipple. N. good. As only well-known symptoms occurred the proving was stopped. – 23rd, 9 a.m., a transient icy cold feeling was experienced in a small spot on the left side of thorax. – 24th, evening, after lying down a sudden horrible pain as from thousands of splinters in the middle of the right forearm, accompanied by a momentary feeling as if he would lose consciousness, when at rest. Thereafter prickings as with splinters for a few m. in right cheek, just below the lower orbital border, that changed into a digging pain as if in the bone. – 25th. An icy cold feeling above the proximal joint of the right middle finger. – 26th. Splinter-pricks on back of right hand near wrist, with frequent twitching of various muscles. – 27th. Frequent pricks as from splinters in dorsal and lumbar vertebrae. – 28th. Sensation in lumbar portion of spinal canal as though the cord or its membranes were touched there with a piece of ice, lasting 20 to 25 seconds. – 29th. Chirping, crepitating and creaking in spinal column. – 30th. At night, splinter-pricks in left sublingual salivary gland, followed by great flow of saliva into mouth. Various symptoms of agaricus action were experienced by prover up to 11th Feb. of following year. They were sometimes mere traces, at other times were as violent as ever. They were not only the well-known symptoms, but several new phenomena occurred. Thus when lying still in bed there was often a peculiar cracking and creaking in the osseous parts of the nose, as though the spongy nasal bones were pressed or forced against one another. For many successive days at the same hours in the m. in bed there occurred a constant chirping deep in the occipito-nuchal region, as if a cricket were in the cervical portion of the spinal canal, lasting 4 to 10 m. One n. his whole household burst into his bedroom to inquire the meaning of a horrible scream he had emitted, but of which he was entirely unconscious. (Ibid.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.