Sleepless night with restlessness and talking nonsense. [MATHAEI, l. c.]

530. Sleeplessness attended by unwelcome visions and full of phantasies, which are ver different from the things around him, as in insanity. [TRALLES, l. c., p. 122.]

Betwixt waking and sleeping dreams and visions of dragors, skeletons, and horrible ghosts and grinning spectres. [TRALLES, l. c., p.125.]

Restless night, sopor alternating with wakefulness, much raving hot skin and stupefaction, during which he lies in a heap. [MATTHAEI, l. c.]

Sleep and redness of face. [BERGIUS, l. c.]

From 108 the pulse falls to 72; at the same time chilliness and shivering, diminished activity, great exhaustion and yet increased hunger. [WARD, Neues Journ. d. Ausland. Medorrhinum Chir., lib. iv, 1.]

535. Diminishes the rapidity of the pulse and respiration. [A THUESSINK, l. c.]

Pulse first 14 beats slower (the first 4 h.), afterwards (aft. 10 h.) 30 beats quicker. [SAM. BARD, (Experiment on self with 1-1/2 grain doses.) Diss. de Viribus Opii, Edinb., 1765. (From rubbing in two drachms of opium – after 50 minutes.) ]

(Circulation diminished by one half. (This was seen by Alston (Edinb Vers., v., pt. I, sect, iii) through a magnifying glass in the foot of a frog, to which he had given some drops of tincture of opium.)

(The heart beats four times slower. [WHYTT, Neue Edinb. Vers., I, art. 19. (In a frog to which opium had been given.) ]

Large slow pulse, with laboured deep breathing. [DE LA CROIX, l. c.]

540. Large slow pulse, with slow, laboured stertorous breathing. [CRUMPE, l. c.]

Slow pulse.

Stronger pulse.

At first full, slow pulse, afterwards weak pulse. [BERGIUS, l. c.]

Slow pulse, with groaning, slow breath, very red, bloated face, and very profuse perspiration with convulsion. [MUZELL, l. c., p. 131. (From laudanum and hreatshorn.) ]

545. Full, regular, slow pulse, with deep stertorous breathing. [SAUVAGES, l. c.]

Weak, suppressed, slow small pulse. [FR. HOFFMANN, Medorrhinum Syst., ii, p. 537.]

He complains of chilliness. [WILLIS,- REINEGGS, l. c.]

Tendency to shiver. [REINEGGS, l. c.]

Diminution of the temperature.

550. Chilliness in the back, with suppressed, scarcely perceptible pulse. [SCHELHAMMER, l. c.]

Chilliness in the back.

Coldness of the limbs.

Thirst during the chill.

Fever; at first chilliness, then flying heat in the face (with white tongue, and perspiration before midnight).

555. Fever; first rigor, then heat with sleep, during which he perspires profusely.

(Fever; he falls asleep during the chill; no thirst during the chill; during the heat thirst and profuse general perspiration.)

In the evening in bed, immediately chill, and as soon as she falls asleep she breaks out in perspiration, which is particularly profuse on the head.

(Fever: Rigor with thirst, then increased heat of the whole body, with tendency to throw off the bedclothes, with strong full pulse, dryness of the fauces without thirst, and liveliness of the ideas and memory)(aft. 1 h.).

External coldness of the limbs. [WILLIS, l. c.]

560. Coldness with stupefaction. [CHARDIN, l. c.]

At first diminished temperature (shown by the thermometer), afterwards increased transpiration. [RONALDSON MARTIN, in vetensk. Acad. Handlung, 1773, pt. ii, No. 7.]

Strong, very quick pulse, which at last (aft. 8.1/2 h.). Becomes weak and inremittent (shortly before death). [ALSTON, (This symptom should read, “Her pulse, which was large, equal, and not very frequent, sank, and began to intermit a quarter of an hour before she died.”) Medical Essays. (From a scruple.) ]

Quick and uncommonly weak pulse, with quick, oppressed anxious respiration (aft. several h.). [GRIMM, l. c.]

Quick pulse with headache. [YOUNG, l. c.]

565. Quick, violent, hard pulse, with dark red face. [VICAT, Obs., l. c.]

Rush of blood to the brain. [HALLER, in Pralect, Boerhavii, iv, p. 509, – MURRAY, l. c.]

(The vessels of the brain were distented with blood, [MEAD, l. c.]

Violent, rapid, hard pulse, with difficult, obstructed respiration. [VICAT, Plantes Venen., l. c.]

Quickened circulation with sensation of heat. [MURRAY, l. c., pp. 281, 282.]

570. The blood-vessels distented. [MURRAY, l. c.]

Increased heat. [MURRAY,- YOUNG, l. c.]

Alternation of moderate heat with cold.


Great redness of face, with burning heat of the body, for eight hours; then convulsive striking out of right arm and leg, with loud cry, difficult breathing and coldness of face and hands, covered with heads of perspiration (shortly after taking it).

575. For six successive evenings, a burning heat in the face and feeling of heat especially in the eyes, without thirst. [Ctz.]

Heat with thirst. [CLARK, l. c.]

Increases the heat of the whole body and leaves dryness of the mouth and thirst. [BERGER, l. c., § 2.]

Sometimes dry, hot skin, sometimes slight perspiration. [YOUNG, l. c.]

Heat of the body with great anxiety. [BERGER, l. c.]

580. Intolerable heat with great anxiety. [MATTHAEI, l. c.]

Acute fever with delirium, which occurred after a short sleep and lasted twelve hours, after which he became very weak and sick, with weak pulse; after three hours, delirium returned which lasted forty eight hours, with strong full pulse; thereafter sleep for eight hours. [J. HUNTER, l. c., p. 641.]

With restlessness, oppression, confused ideas and sparks before the eyes, there rises up a burning disagreeable heat into the head which then spreads all over the body. [MATTHAEI, l. c.]

Perspiration (“Thick sweat” in original.) first on the head then all over the body, like drops of dew, and sleep. [MATTHAEI, l. c.]

Increased transpiration.

585. Perspiration only on bodily exertion.

General perspiration.

In the morning, during sleep, perspiration all over, with inclination to uncover himself (aft. 12, 36 h.).

Cold sweat on the forehead.

Perspiration only on bodily exertion.

General perspiration.

In the morning, during sleep, perspiration all over, with inclination to uncover himself (aft. 12, 36 h.).

Cold sweat on the forehead.

Perspiration especially on the upper parts, whilst the lower parts are hot and dry. [MATTHAEI, l. c.]

590. Almost always induces perspiration. [BERGER, BUCHNER, FRIEND, GEOFFROY, HALLER, PITCAIRNE, THOMPSON, WEDEL, l. c.]

Frequent perspiration. [MUZELL,- TRALLES, l. c., p. 134.]

Profuse perspiration (During convalescence.) (for 12 h.). [VICAT, Pl. Ven., l. c.]

General perspiration (aft. 6 h.). [GRIMM, l. c.]

During tolerably quiet sleep, profuse perspiration. [MATTHAEI, l. c.]

595. Perspiration very profuse, so that the skin itches and is covered by an eruption, whilst all the senses become blunted – touch, vision, and smell. [MURRAY, l. c.]

Perspiration and red miliary rash with itching, [TRALLES, l. c., p. 138.]

General perspiration of the extremely hot body, with great thirst, full, strong pulse, bright eyes and active mind. [MATTHAEI, l. c.]


Alternating state of careless sulleness and cheerfulness.

600. Taciturn reserve (after the smallest dose).

Tranquil indifference to earthly things; she cared for nothing in comparison with the ecstasies of the phantasy. [MEAD, l. c.]

Always quiet cheefulness of disposition; as if in heaven [HECQUET, l. c.]

Free from pain he remained the whole night in extreme cheerfulness of mind. (He had taken a grain in the evening for a very annoying pain.) [VAN SWIETEN, Comment., I, p. 878.]

The most agreeable sensation that can be imagined, with tranquility of mind and forgetfulness of all ills. [VAN SWIETEN, l. c.]

605. In no other way could she procure for herself complete tranquility and happiness of mind. [JONES, The Mysteries of Opium, revealed. (Observations.) ]

Not often an uncommon self-satisfaction and unusual tranquility of mind. [MOS. CHARAS, l. c.]

He did nosleep, but became as tranquil as if he were in heaven. [Eph.. nat. Cur., Dec. ii, ann. x, obs. 80. (After taking a moderate dose of opium for intolerable pain from stone.) ]

Sweet, delightful phantasies, which she prefers to all known happiness, chiefly when she had previously been tortured with pains. [BOEERHAVE, Praelect, in Inst., ad. § 856.]

Sensation as if he were in heaven, strong, delightful phantasies hover before him like waking dreams, which drive away sleep. [MEAD, l. c.]

610. The cheerfulness of mind from opium may rather be called a dream without sleep.[TRALLES, l. c., p. 122.]

Tranquility of mind. [DE RUEF, l. c.]

Activity of mind. [DE RUEF, l. c.]

A woman subject to melancholy thoughts is wonderfully relieved by it; her sorrow ceased for some time. (But, as it acted antipathically (palliatively), in order to procure the same relief, she must not only continue the use of opium, but increase the doses, so that at last she was obliged to take an ounce and a half of opium in one week.)

It causes the mental sufferings to be forgotten for a time and brings on an ecstasy and refreshing happiness of mind. [TRALLES, l. c., p. 98.]

615. It makes the (usually sad stupid) opium-eaters happy; they are very riotous, sing amorous songs, laugh much and play other pranks; this agreeable elevation of mind and disposition lasts an hour, then they became angry and uncontrollable, after which they again become sad and weep, until they go to sleep, and thus again return into their previous state. [ALPIN, l. c.]

Samuel Hahnemann
Samuel Hahnemann (1755-1843) was the founder of Homoeopathy. He is called the Father of Experimental Pharmacology because he was the first physician to prepare medicines in a specialized way; proving them on healthy human beings, to determine how the medicines acted to cure diseases.

Hahnemann's three major publications chart the development of homeopathy. In the Organon of Medicine, we see the fundamentals laid out. Materia Medica Pura records the exact symptoms of the remedy provings. In his book, The Chronic Diseases, Their Peculiar Nature and Their Homoeopathic Cure, he showed us how natural diseases become chronic in nature when suppressed by improper treatment.