Lateral headache, early in the morning, with fear of opening his eyes, because he feared it would increase the pain (second day).
Noise affects me (child crying); caused lateral headache (third day). Lateral headache, which seems deep in the brain, nearly always relieved by eating (after four days); coming on while riding in a carriage (seventh day). Sharp headache on right side, transient (tenth day). Some headache; worse on right side (ninth day). Occiput and External. Dull pain in left occiput, lasting ten minutes (five minutes, after second dose). Occipital headache, more of a tired sensation, in cerebellum (sixth day).
Contracted feeling of the forehead, which extended to the eyelids, causing an effort to close or open them (second day). A burning spot in center of forehead (third day).
Eye.
Left eye was red and swollen (fourth day). Right eye first inflamed, then the left; sclerotic red, dry, and swollen; eyes feels best when closed. Burning of eyes, and bloodshot appearance of them, all the forenoon (eleventh day). His father stated that “his eyes were working” or as his mother said, “as if the nerves were upon him.” (Eyes unusually free from black spots, in the morning), (second day). Eyes very dull and heavy, at 2 P.M.
(fifth day). Eyes heavy. Eyes sleepy like. Great pressure on the eyes, with muscae volitantes. The medicine affects the slight very much, producing these spectres constantly fitting before the sight; long snakes or worms, both dark and light; also waves before the eyes, giving objects a tremulous motion, as if it gave the same quality of involuntary motion to the optic nerve that it does to the motor nerves, and made the sight movable; also a slight sensation of double sight, as if the images of objects would be multiplied (seventeenth day). Continued drawing twisting sensation in the eyes (thirteenth day). Sharp shooting and drawing sensation in the right eye, at 1 P.M. (fifth day).
Drawing twisting sensation in the eyes, at 3 P.M. (fifth day).
Since 11 A.M., have had great drawing twisting sensation in the eyes, at 8 P.M. (tenth day). Drawing sensation in the eyes, at 6 P.M. (third day). Eyes are sore, and give pain when moved from side to side, at 6 P.M. (second day). Eyes smart; lids feel sore (third day). (Was asked by a physician if I do not suffer from diplopia, as the muscle internus seems not to do its work rightly, and the axis of the eyes differs in each; but my eyes only felt weak, with lachrymation, especially of left eye, from which I suffer when having my usual headaches), (sixth day). Slight aching pain in left eye (after five hours). Felt film over the eyes, and blur; objects mixed (after ten minutes); after which dull pain over the eyes, and between the eyes, lasting for one hour; sometimes have had similar feelings, but not often. Pain in the left eye, with muscae volitantes. Eyes feel weak (third day).
Eyes sensitive (eighth day), and feel weak (ninth day). If a very weak solution is used, so that the accommodation is not markedly affected, we find that on attempting to use binocular vision, as in reading, a disturbance exists, consisting of pain, blurring, and straining, so that one eye must be closed, which is relieved by a weak concave glass; it seems as though the ordinary will, impulse, caused too great an action of the accommodation. Had the symptoms in the eyes all the morning, with much burning of the balls (sixth day). Orbit. Aching pain in posterior part of orbit, extending back into the brain; worse on reading (aches so cannot read), causing nausea (second day). Lids and Lachrymal Apparatus.
Twitching of upper eyelids, at 4 P.M. (fifth day); of left most, which is very annoying (seventh and ninth days). When the accommodation becomes affected by Physostigma, twitchings (spasmodic) of the lids ensue. Sensation of contraction of the eyelids, with difficulty of opening them, and a suffusion of tears when wide open (after fifteen minutes); it required an effort to keep the left eyelid open; this lasted till night, with pain in right side of upper jaw (second day). Cannot bear to raise the lids (sixth day). If Physostigma is applied to the lids it produces immobility of them. Eyelids feel heavy (second and fourth days). Lids, which are usually heavy, were less heavy, and can look more steadily at an object; but lids grow heavier again later. At night, intense itching of the edges of the eyelids and inner canthus of the right eye (sixth day). Eyes suffused with tears (after seven hours and a half, second day). Ball. Pain in the eyeballs (third day). Severe pains in the right eyeball, darting from within outward; relief from pressing on the eyes; the pain continued at intervals, from 6 1/2 to 10 P.M., when it seemed to shift to the supraorbital ridge, and continued till about 12 (after eleven hours and a half). As soon as I got, up, at 7 A.M., experienced severe darting pains in both eyes; pain darting outwards; experienced no pain after breakfast; as soon as I sat down to study, at 7 P.M., had the same darting pains in the left eye and superciliary ridge; same character of pain, and relieved by pressure and moving about; pain gradually diminished until 11 P.M. (second day). Pain, with sharp stitches, in the ball of right eye, and in the frontal bone, with a distinct pain running obliquely into the temporal bone, in the evening (first day). Pain deep in, over top of ball; ran up from inner canthus to the right frontal eminence, then down obliquely outward into temple; dull miserable pain; same in eye and forehead returned, not as severe, but more general over the forehead, relieved by motion out of doors (second day). A drawn, twisted sensation in the eyeballs, at 8 P.M. (second day); especially in the right, at 7 P.M. (third day). Towards the end of the myotic action there is experienced a painful tension, partly in the equator of the ball, partly in the ciliary region. Great fullness of the eyeballs, as if they were too large, with a sensation as if the lids were too tight on closing them (first night). Swollen sensation, with burning in the eyeballs (third day). Nervous achings in the whole ball, which extended along the supraorbital nerves, and over half the head. The circulation in the fundus of the globe is not affected. Pupil. Decided dilatation of the pupil, very soon.
Pupils dilated (third day). After the myosis had passed off there is usually mydriasis of a slight degree for several days, especially during the morning hours; this seems to depend upon a kind of fatigue of the sphincter, which passes off during the day under the reflex stimulus of light. A very slight dilatation of the pupil was perceived. The myotic effects of the extract began to be noticed after fifteen to thirty minutes; the maximum contraction was obtained in from thirty to forty minutes; the myosis continued stationary from twenty minutes to three hours; the action of the drug was limited to the eye to which it was applied. On carefully watching the progress of the myosis (contraction of the pupil), the iris is seen to contract convulsively with little jerks or twitches; they are very small and rapid jerks, and would easily escape observation. While the iris was under the influence of Physostigma in all stages it was sensitive to light, that is, it would contract still more from a sudden strong light, even when the myosis had reached a high grade; this seems to show that the sensibility of the retina remains unaffected. The myosis lasts from two to four days.
Pupils contracted (fourth, fifth, and sixth days); very much contracted (eighth day). Pupil very much contracted (after one hour). Pupils contracted (second day); (second morning); (fourth and eighth days). In about two-thirds of the cases the pupils were contracted, and there was double vision. Not only was the pupil of the healthy eye rapidly contracted, but even the paralyzed pupil, which, before the application, measured three and a half lines, was contracted to two-thirds of a line (the size of a pin’s head), within half an hour after the instillation of the extract. The maximum of contraction of the pupil was the same in each eye, but the left regained its original size sooner; it also always remained active under the influence of light, whereas the right was quite immovable. The sight of the right eye also rapidly improved, for within a quarter of an hour of the application she could read with it the very finest print, and this whilst its pupil was two and one- third lines in diameter.
The effect upon the ciliary muscle was more marked in the left than in the right eye, for in the former the near point was approximated to three inches, the far point was approximated to three inches, the far point to five and a half inches; in the right eye the near point was never brought closer than eight inches, nor the far point nearer than eleven inches. Stronger concave glasses were consequently required for distant objects by the left than by the right eye. The effect upon the accommodation also ceased much sooner in the right than in the left eye, for in the former the myopia had disappeared five hours after the application, whereas six days afterwards the sight of the left eye for distant objects was still improved by a concave glass of thirty-six inches focus. In a woman aged twenty-four, the sight of the right eye was so far impaired that she could only distinguish light from darkness, that pupil being very sluggish under the action of light, and much larger than its fellow. I applied a drop of the weakest solution between the lids of the right eye; after half an hour the pupil had become so contracted that it was only about half the size of the other one. In an experiment on another woman, the pupil of the eye to which the solution was applied was contracted one-half after fifteen minutes. Third experiment: a drop of the weak solution was applied between lids of right eye; no visible change in the left pupil was perceptible (after eight minutes); it had become slightly contracted (after twenty-three minutes); contracted to half the size of its fellow (after twenty-three minutes); contracted to half the size of its fellow (after twenty-six minutes); it was less than half as large as its fellow (after twenty-eight minutes); this pupil was only about equal to a pin’s head in size, the pupil of the other eye having become larger than it had previously been (after thirty-three minutes). Fourth experiment: I applied a drop of the weakest solution between the lids of the right eye; no visible change (after eight minutes); pupil contracted to the size of a pin’s head (after eight minutes); pupil contracted to the size of a pin’s head (after twenty minutes); very much contracted, but not to so great a degree as before (after nine hours); still contracted, but almost as large as the other pupil (after twenty-one hours). The women first mentioned had the stronger aqueous solution applied between the lids of the right eye; the pupil was reduced to the size of the pin’s head (after twenty-seven minutes). A women of middle age had applied to left eye a drop of the weaker solution, now some days old; no change (after sixteen minutes); a drop of the stronger solution more recently made was applied; in four minutes more the pupil was slightly contracted, and in twenty minutes still later very much so. Pupils slightly contracted.
Born in 1837in Westminster, Vermont. . He was an orthodox doctor who converted to homeopathy
Dr. Allen compiled the Encyclopedia of Pure Materia Medica over the course of 10 years.
In 1881 Allen published A Critical Revision of the Encyclopedia of Pure Materia Medica.