Physostigma



Slight difficulty in walking (after seventy-five minutes); great difficulty (after one hundred and ten minutes). Staggered and was scarcely able to walk. Staggering gait. Staggering on attempting to walk. Could neither stand nor walk. Hip. Stiffness in the hip and knee-joints (after two days); continued stiffness of lower limbs (fifth day); slight stiffness (eighth and thirteen day).

Slight stiffness in the left hip, at 7 P.M. (third day). Slight stiffness of the left hip and right knee, at 9 P.M. (fifth day).

Slight stiffness in the left hip, at 2 P.M. (second day); at 9 A.M. (third day); still continues (fourth and eighth days). Left hip and right knee quite stiff, at 6 P.M. (third day). Stiffness in the hip and knee-joints (fourth to eighth day). Thigh. Severe cramp like pain in the left popliteal space; walking was very painful; it lasted two hours, gradually passing off; during rest the pain ceased, but commenced again on motion; but by continued motion it was relieved (one hour after second dose, seventh day).

Pain in the left thigh, and in both knees, after walking only a few steps, about noon (fourteenth day). A few thrusts with an aching sensation down the left thigh, (after thirteen hours). In the afternoon, when walking, felt a stiffness in both recti femoris muscles (second day). Frequent paroxysms of muscular twitchings in the lower third of vastus externus muscles; these paroxysms came on every time I sat down, and so continued all day (third day). Severe aching in glutei muscles, right side, neither increased nor diminished by walking (third day). Knee and Leg.

(The knee was better, in the morning), (second day). A numb pain was felt in the knees and ankles, while sitting, with desire to move frequently (third day). Pain on the outside of knee (thirteenth day). Shooting pain under the left knee, near or in the popliteal space, returning again and again (after twelve hours). Going downstairs, pain under the patellae of both knees (fourth day). Weakness in the right knee, at 9 A.M. (third day).

On waking, feeling of unsteadiness from knees downwards, so that he had to tread carefully, especially when eyes are shut; feels as if he must look to see where he is going. On going out in open air must take a stick to steady himself, and has a feeling of weakness about the ankles. Determined exertion of the will relieves the unsteadiness (second day). Cramps in calf of left leg, in bed. Intermittent, momentary constrictive pain around the left leg, just about the ankle (after eleven hours and a half).

Sense of weight in the legs (after two days). A sensation as of a drawing of cords behind the leg and the knee, making it hard to walk, especially upstairs, at 6.30 P.M. (eighth day). Gnawing sensation in the left tibia, at 2 P.M. (second day); at 9 A.M.

(third day); still continues (fourth and eighth days). Gnawing sensation in the left tibia, at 6 P.M. (third day). Sharp twinges in the right instep (after half an hour). Foot and Toe. Cramp in the left foot, in the evening, while in a warm bath (thirteenth day). Numbness in left foot. Pain in right great toe, transient; ache around the toe.

Generalities

Only one case proved fatal, a boy of six years, who ate six of the beans and did not vomit; he lived about two hours. The appearances presented were as if the nervous system bad received a great shock, amounting to complete collapse, in the worse cases. Looked sleepy, listless, and depressed, and begged to be put to bed. Collapse after the vomiting. Convulsions and twitchings (especially in the back); death in thirty minutes.

Trembling of legs, as if I could not walk straight, at 7.30 A.M.

Seized with violent trembling all over, in the street, at 9.30 A.M. Felt for an instant as if I should lose consciousness, and could hardly get home; riding in a car for twenty minutes did not relieve the sensations; these trembling spells came on in fits, and at the least thing that startles; at 10.30 A.M. trembling of hands, so that I could hardly sew; this spell lasted an hour, when the soreness at the pit of the stomach came on (seventeenth day). Almost instantly felt a shuddering and trembling run down through all the nerves of the body; the sensation appeared to begin in the head and run down through the pit of the stomach, where they were strongest of all, and through in the middle of the forehead, between the eyes, above the over, and in the left eye a pain, with muscae volitantes. Very restless through the night (first night). Somewhat restless towards morning (first day). Very restless in bed, not feeling satisfied in any position, at 10 P.M. (fifth day). Quite restless through the night (seventh night). Very restless, moving from side to side, throwing the arms about the head, but no position seemed to afford relief (tenth day). Restless (first, second, and third nights). A constant desire to change from side to side. Feeling of great debility (after six hours and a half, third day). Great sense of fatigue (general), as from long-continued labor, with fullness in forehead, and tendency to ache, mostly right side, continuing through the afternoon (after five hours). Rather fatigued during the forenoon (second day). Sensation of general fatigue, with the headache (after four hours). Disinclination to move (fourteenth day). General weariness of whole body; easily exhausted upon going upstairs; greatly exhausted after a stool (third day). Very weak, especially in groins, at 9 A.M.; some weakness of body, and easily exhausted, at 9 P.M. (fourth day). A little weak (fifth day). Easily exhausted (sixth day). General weakness and third feeling; weakness after stool; great weakness of right side (eighth day). Great weakness and stupidity; feel as if I had been out carousing the night previous (or as those feel who do go out carousing at night), (ninth day). Some weakness, at 9 A.M.; tired feeling, at 10 P.M. (tenth day). Easily exhausted (eleventh day). Some exhaustion on walking (twelfth day). Great deal of weakness and torpor since taking the medicine (eighth day). A steady erect position was with difficulty retained while going through with the dumbbell exercises (after twenty minutes); muscular weakness still experienced (after two hours and ten minutes). For the rest of the forenoon I felt to weak to leave my bed (five hours after 12 grains). Felt stupid and giddy as she walked along the street, with a sensation of a great feebleness over the whole body, rendering progression a matter of difficulty. Much weakness and leucorrhoea, at 4 P.M. (eighth day). Sense of weakness, extending from the head downwards through the back and legs, attended in the legs by the thrilling sensation heretofore described; slight exertion caused lameness and weakness in small of back (after three hours). During the forepart of the day (which was sultry) he had at times a feeling of weakness, though there was uncommon mental activity (second day). On walking became excessively tired; could hardly get along (fourth day). Muscular weakness on going upstairs (third day).

Muscular weakness (after ten minutes). I tried to raise myself on my elbow to vomit, but failed; I made a second, more vigorous, effort, but scarcely moved; at once it struck me, “This is not debility, but volition is inoperative;” in a third effort I was more nearly successful, and in the fourth, a resolute exercise of the will, I did succeed, but could not vomit; the abdominal muscles acted too feebly, nor were they much aided by a voluntary afford to make them act (after 12 grains). Felt very languid and dull (second day). Feeling languid, at 1 P.M. (second day).

General languor (ninth day); (8 A.M., sixth day); (9 A.M., third day). Very marked sensation of languor and indisposition to move, but by an effort of will my muscles were as fully under my control as before. General lassitude and dizziness; had to stop reading. Some lassitude (third day). Her whole frame seemed lessened and powerless (second day). Complete muscular relaxation, with continued fibrillar twitchings of the muscles.

Quite prostrated. Very prostrate and pale (forty minutes after 12 grains). Appeared to be perfectly prostrated. Great prostration of muscular system; feel as if I had taken a five-mile walk (after one hour and a quarter); still have this same feeling of prostration, with some headache, at 12 M.; prostration not so marked, at 10 P.M. (second day); prostration and headache light, at 12 M. (third day). Prostrated; felt severely indisposed; had to lie down and wanted the doors to be shut (third day). Complete relaxation of the whole body, as if every nerve were unstrung, even to the eyes, which felt as if all power to see were going out of them, at 6.30 P.M. (eighth day). Great feeling of prostration, nervous, tremulous, especially felt in the left arm, at 7 P.M. (third day). General feeling of prostration, at 8 P.M.

(fourth day). Felt completely prostrated and obliged to lie down, at 10 A.M.; only wanted to be left along, be well covered with woolen blankets, shut my eyes, and doze away the time, at noon (third day). All I wish is to rest and sleep, if the gripes would only allow it (fourth day). As the day wore on a general prostration set in again, as if my feet were too weak to hold me up; reading was tiresome; and speaking an effort; I tried to walk out, but had to give up on account of general prostration and soreness of bowels, produced by the motion (sixth day). Extreme faintness, not, however, unpleasant (forty minutes after 12 grains). Faintness with the dizziness (fourteenth day). Attacks of faintness (after a quarter of an hour). Sensation of faintness, with the trembling of the nerves at the pit of the stomach (fifth day). Great aversion to usual cold bath (third day). Very great reluctance to take my accustomed bath; felt uncomfortable after bathing; did not enjoy the bath (second day).

TF Allen
Dr. Timothy Field Allen, M.D. ( 1837 - 1902)

Born in 1837in Westminster, Vermont. . He was an orthodox doctor who converted to homeopathy
Dr. Allen compiled the Encyclopedia of Pure Materia Medica over the course of 10 years.
In 1881 Allen published A Critical Revision of the Encyclopedia of Pure Materia Medica.