Chininum Sulfuricum



Urging to stool, without subsequent evacuation (fourteenth day). Urging to stool, without subsequent stool, in the forenoon (fifth day). Urging to stool, in the evening, with passage of very difficult small soft stool (fourteenth day). Urging to stool, with slight griping in the abdomen, followed by a natural stool at 2 P.M. (fifteenth day).

Stool.

Diarrhoea.

Diarrhoea (eighteenth day). Diarrhoea, with violent colic- like pains across the abdomen (thirty-first day). Diarrhoea-like stool, with drawing and cutting in the intestines, at 6.45 A.M. (twenty-fourth day). Stool at first mushy, then like diarrhoea, preceded by excessively offensive flatus, at 9 A.M. (twentieth day). Some thin stools. Repeated stools, thinner and lighter color than usual. Four stools, first normal, the others liquid (first day). Stool (after exertion of the body) postponed by circumstances; soft, except the very first; came away suddenly, partially arrested by a cramp like contraction of sphincter, concluding as this gradually subsided; followed by painless prolapse of mucous membrane, etc., like piles, on right side (same as for some time past, but more pronounced), requiring replacement, and sitting on it to retain, for awhile (eighth day). After breakfast, good stool, yellow, soft, with yellow- tinted clear mucus; protrusion of right rectal fold considerable, requiring reduction with sweet oil, followed by pressure of cushion, to retain it (fourteenth day). Stool at first solid, then liquid, at 11 A.M. (twenty-seventh day). Stool, with yellow mucus, after breakfast (forty-second day). Constipation.

Stool hard, crumbly (second day). Stool harder than usual.

Stool very hard (sixty day). Stool at first hard, afterwards thin (fifteenth day) Postponing stool, it proved scanty, with the habitual protrusion (fifteenth day).

Stool with exertion and pain to-day (eleventh day). Stool difficult, faeces of ordinary consistence. Stool not very hard, but difficult to pass, always with the peculiar sensation extending from the right hand to the shoulder, as before noticed. Defecation this morning, a little sluggish, and rather incomplete in amount (twelfth day). Defecation attempted at a later hour than usual is very incomplete and difficult; the peristaltic action deficient, and the sphincter contraction too great (usual in like circumstances) (seventh day). After breakfast, imperfect defecation; painful spasmodic resistance of the inner sphincter; afterwards marked protrusion, with difficulty of manual reduction, and irritability; better by applying cold water, then oil, and sitting on cushion as before. Stool contained some yellow mucus (twenty-fifth day). Constipation. Constipation, for one day. Obstinate costiveness (14 to 16 grains daily). No stool, with distension of the abdomen (fourth day).

Urinary Organs.– Bladder.

Catarrhal inflammation of the urinary bladder. Urethra.

Constrictive biting pain in the orifice of the urethra after urinating, at 9 P.M. (seventeenth day). When going about the room, desire to urinate, with colic in transverse colon; urination normal, in the afternoon (fourteenth day). As in several other instances, had to rise early in the morning to urinate (at ordinary times more during the night), (twenty-fourth day). Urging to urinate, with passage of 16- 1/2 ounces of watery, straw-colored urine, which does not redden litmus-paper (after one hour and a quarter). Micturition. Urine increased to double the usual amount, although he did not eat (twenty-sixth day). Urine copious, high-colored, turbid (second day). Urine scanty and turbid. Secretion of urine increased; urine deposited a large quantity of orange-colored crystals, shown under the microscope to be right-angled prisms, with rhomboidal fragments. Increased secretion of cloudy urine for several days. Increased secretion of urine, preceded by distension of the upper and lower abdomen, and oppressed respiration. Passage of much urine, with much thirst and drinking, without deposit of crystals (fourth day). 14 and 8-1/2 ounces of urine passed at 5 and 10 A.M. respectively; it was of a strong urinous odor, and turbid; 63-1/2 ounces was the aggregate amount of seven passages (second day). 25 ounces of urine in four passages, and containing many crystals (tenth day). 29-1/2 ounces of urine in four passages, depositing 1-3/4 grains of crystals (ninth day). 46-1/2 ounces of urine in six passages (fourteenth day). 50-1/2 ounces of urine in four passages, high colored, and very acid, without sediment (fifteenth day). Urine, 51 ounces in five passages, depositing a loose, yellowish sediment, and a large number of orange-colored crystals. (* These crystals consisted of urate of ammonia and phosphates, and traces of quinine. *) 60-1/2 ounces of urine in seven passages, pale yellow; the sediment was small, like brown granules, and seemed to be conglomerated crystals, but much smaller than on the previous day, and did not show the concentric layers (sixteenth day). 61-1/2 ounces of urine in seven passages, high-colored, with a deposit of yellowish-red crystals (twentieth day). 66 ounces of urine in eight passages; a crystallized deposit the next morning like a conglomerate of candied sugar, in which regular forms could not be distinguished, consisting of urate and purpurate of ammonia, with phosphates (seventeenth day).

70-1/4 ounces was the aggregate amount of seven passages of urine (first day). Urine, 99-1/2 ounces in eight passages (thirteenth day). Flow of urinary residue after replacement of clothing after urinating, occurred once (thirty ninth day).

Urine. Urine, clear, pale, increased in quantity, even if nothing had been drunk. Urine high-colored, 40-1/2 ounces in five passages (eighth day). Urine high-colored, having a strong urinous odor and acid reaction, 80-1/2 ounces in nine passages (seventh day). Urine high-colored; on cooling it deposited a thin, powdery, yellowish-white sediment (third day).

Decided dark color to urine after thirty-five minutes, becoming darker, and even a dark orange color, with decided sediment after four hours; tests demonstrated Chinin in the urine. Urine very frothy. Urine turbid (second day). Decided turbidity of urine after fifteen minutes; a thick, chocolate- colored sediment, with great turbidity (Chinin found in urine). Hemorrhage of the urinary passages (on one occasion profuse), (in a boy and a girl whenever the drug was administered). Urine as clear as water, containing, the next morning after the chill, a number of clear transparent crystals, shown under the microscope to be four-sided prisms, with four-sided pointed ends (about one fourth of a grain of these crystals in 10 ounces of urine); the crystals were enveloped by tough mucus, as with a spider!s web (fifth day).

(* An analysis of these crystals showed that phosphates of ammonia and magnesia were certainly present; lime was not present, but soda was, which seemed to determine the peculiarity of these crystals, differing somewhat from the pure triple salt of phosphate of ammonia and magnesia. *) Formation of crystals in the urine (character not mentioned). Urine deposited crystals of prisms of three-sided pointed pyramids (fourteenth day). Urine deposited crystals as before (twenty-third night). Deposit of crystals in the urine continued daily.

Urine deposits a red sediment (fourth, fifty, sixth and succeeding days). Urine deposited a rose-red sediment which under the glass showed rhomboidal flat crystals, with here and there double pyramids. (* These crystals were not soluble in alcohol nor cold water, but were dissolved by boiling water, which redeposited a sediment after cooling; this sediment contained only traces of uric acid, consisting almost wholly of phosphates. *) Brickdust sediment in the urine. Urine deposited a thick brick dust sediment. A brick dust sediment in the urine of the previous day, consisting of adhering brown grains of the size of poppy-seeds, having the external appearance of gravel; they were round, oval, and kidney shaped; one of the larger showed under the glass several concentric layers of a bright color; under a magnifying power of three hundred they seemed of the size of a bramble (Rufus calsius) berry, and the surface had the appearance of a collection of beautiful crystals (fifteenth day). (*One-quarter of a grain of these crystals was collected from a pound and a half of urine; they contained urate and ‘purpurate’ of ammonia mixed with phosphates. *) From the nineteenth to twenty-third day, the urine deposited a straw- yellow, granular sediment, mingled with transparent, glittering, perfectly colorless crystals. Urine deposits a yellowish white sediment, adhering to the vessel and of a strong odor (fourth day). On the vessel is a light-colored, mealy deposit, containing two grains of glittering crystals, showing facets on all sides, consisting of urate of ammonia, phosphates, and sulphate of chinin (seventeenth day). The solids in general, and the urea, I found not materially affected under the influence of quina, but the phosphoric acid appeared to be augmented. In the first experiment I took 20 grains of disulfate of quina in the course of the day, and during the next forty-eight hours the excretion of uric acid amounted in all to 0.542 grammes, less than half my normal quantity. The quantity of uric acid excreted during forty- eight hours, after 15 grains of quina had been taken, was equal to 0.790; on the third day, after quina had been taken, I excreted again about my normal average, namely, 0.621 grammes; and on the two following days 0.543 and 0.656 grammes respectively. I now took quina for a third time, and the quantity of uric acid again fell to 0.438 grammes on the first, and to 0.192 grammes on the second day. Dr. S. excreted during the two days previously to his taking quina 0.544 and 0.543 grammes of uric acid. On the third day he took 20 grains of disulfate of quina, in two 10 grain doses, and on that day he excreted 0.376 grammes of uric acid. The next morning he again took 5 grains of quina, and the quantity of uric acid subsequently fell to 0.317 grammes. During the three following days he excreted 0.483, 0.460, and 0.654 grammes respectively.

TF Allen
Dr. Timothy Field Allen, M.D. ( 1837 - 1902)

Born in 1837in Westminster, Vermont. . He was an orthodox doctor who converted to homeopathy
Dr. Allen compiled the Encyclopedia of Pure Materia Medica over the course of 10 years.
In 1881 Allen published A Critical Revision of the Encyclopedia of Pure Materia Medica.