24. Dr. FREUD, aet. 25, May 28th, 6 a. m., 6 dr. tinct. 10 p. m., same dose. – 29th, 6 a. m., 6 dr. No symptoms these 2 day except constipation. – 30th, 6 a. m., 6 dr. Sudden call to stool, which was soft. – 31st. No med. M., a pappy, soft, copious stool. In evening a violent pressive headache till bedtime. – June Ist, 8 a. m., 6 dr. Very little appetite for dinner. In evening when sitting playing had a sudden faintness, so that he could scarcely sit on his chair. Lay down on sofa and the face was sprinkled with cold water, which soon revived him. – 2nd. Only slight exhaustion remained, and he had a coryza with cough that lasted 4 day (Ibid., 50.)
25. a. Surgeon JENITSCHEK, June 3rd, 1 1/2 hours before breakfast, 3 dr. Ist dil. Soon fulness and tension in abdomen. – 4th, m., 5 dr. No stool (was used to have 2 stools, one before and the other after breakfast). 8 a. m., uncommonly sleepy, great forgetfulness, fearfulness, with giddiness and excited condition, so that he was several times in danger of being run over. As the day advanced became cheerful. At 7 p. m. a copious firm stool. – 5th. Took 5 dr. No symptoms except irritability. – 7th, 6 a. m., 10 dr. After 1/2 hours pain in forehead, forehead felt warm. Peevish humour. – 8th. 10 dr., no symptoms. – 9th. 10 dr., no symptoms. – 10th and 11th. Frontal pain in afternoon; it was intolerable on the 11th, it was a boring pain, intermittent, and spread from forehead to crown. Tongue furred, sticky pasty taste; but the stool was regular on the days when no medicine was taken. – 13th, afternoon, 15 dr. At 6 p. m. fulness in head, vertigo on stooping, tinnitus aurium and distinctly – felt pulsation of cerebral vessels, increased saliva, furred tongue, complete constipation; urine turbid, dark red, saturated, frothy, with reddish – yellow greasy sediment. – 14th. 15 dr., no symptoms except scanty, costive stool. – 15th. One hours before dinner, 15 dr. After dinner, when lying on sofa a painful beating and visible rising and falling of the full stomach synchronous with pulse, so that he could not bear to lie on his back, but must get up and walk about; this gradually went off in 1 hours – 16th m., 15 dr. No symptoms. – 19th. 20 dr., no symptoms. – 20th. 30 dr., and same dose on 21st. No symptoms.
b. June 24th, 4 p. m., 3 dr. tinct. No effect. Continued taking ever – increasing doses up to 15 dr. till July 6th without effect. – 7th, 4 p. m., 30 dr. 6 p. m., feeling of anxiety, weight in chest, must often breathe deeply, occasional gasping for breath, clothes felt too tight, heart’s beats not felt; skin hot and its blood – vessels full. Later in evening nipping and pinching in belly, and all through n. noisy emission of a large quantity of inodorous flatus and occasional eructation of air, which continued during next day – 8th. Early in m. a liquid, frothy, copious stool with great relief. Forehead confused, thickly furred tongue, pasty taste, redness of conjunctiva and increased secretion of tears; felt very exhausted, prostrated, and cross; felt as if he had passed a sleepless n. after a debauch. – 9th, afternoon, 30 dr. Recurrence of the pinching in belly, emission of flatus, distension of abdomen; in evening a liquid stool. – 10th, m., 3 liquid stools with tenesmus and burning in rectum and anus; urine increased, at first dark coloured, afterwards less so. From nose and mouth there came a yellow, viscid, mouldy smelling mucus. As he felt great loathing at the medicine he took no more. (Ibid., 51.)
26. a. W. JENITSCHEK, aet. 9 1/2, June 4th, 3 dr. Ist dil. Soon, pressive headache in forehead, pressive pain in left hypochondrium, nausea, increased saliva for 2 hours – 5th, m., 5 dr. After 1/4 hours complained of frontal headache, forehead felt warm for 1 1/2 h. Afternoon, kept eyes open by effort, they felt dry and as if dust were in them, had to rest them frequently; increased redness of palpebral and conjunctivae. Constipation; skin dry, hot, and turgescent – 6th. 5 dr., frontal headache, constipation, and increased turgor vitalis. – 7th. No med. Stool normal. – 8th. 8 dr., frontal pain and eye symptoms as before, but the eyes were full of tears. Rumbling and pinching in bowels, sweet taste, constipation. – 9th. 8 dr., frontal pain and increased temperature, constipation. Urine in forenoon turbid and dark. – 10th, 4 p. m., 8 dr. 6 p. m., tongue furred, pricking in belly, constipation. – 14th, afternoon, 10 dr. evening, headache, transient shoots in head, noise in ears, furred tongue, scanty stool, hot skin. – 15th. 10 dr., some confusion of head. – 16th. At bed – time 10 dr. No symptoms. – 20th and 21st. 15 dr., no effect. – 22nd and 23rd. 20 dr., no effect.
b. 24th and 25th, 2 dr. tinct. No effect. – 27th. 5 dr., some pricking frontal pain and increased warmth of forehead. – 28th. 5 dr., besides yesterday’s symptoms constipation. – 29th. 5 dr., same symptoms. – 30th. 5 dr., shooting, throbbing, frontal pain, heaviness of head, feeling of a heavy body in it, swaying to and fro, increased heat of body. Burning shooting pain in right wrist, and on back and palm of hand some pimples the size of peas which rose in blisters. evening, 2 similar but smaller on right cheek, painful when pressed; constriction of stomach, constipation and lachrymose disposition. – From July Ist to 4th, 5 dr. Frontal pain, vertigo with swaying of body, objects seemed smaller. The blisters of yesterday gone, but others rose on the side of the neck; they were not red but tender. – 4th to 7th. No med. No symptoms, the pimples gone. – 7th, 4 p. m., 10 dr. Hard stool. – 8th. 10 dr., hard stool. – 11th and 12th. 15 dr., no effect. – 13th, 10 a. m., 20 dr. In afternoon a liquid stool. – 14th. 20 dr., 4 diarrhoeic stools. (Ibid., 56.)
27. Surgeon A. SCHAUER, aet. 27, June 8th, 20 dr. tint. 11 a. m., slight discomfort, confusion of head especially in forehead, lachrymation and burning in eyes, weariness of lower extremities. 2 p. m., these symptoms increased, and in addition a tiresome pain betwixt shooting and boring in coronal and sagittal sutures. Slight redness of conjunctiva of ball and lids, slight swelling of caruncula lachrymalis. Tongue furred more than usual. Little appetite for dinner, after which irresistible drowsiness; an empty almost pressive feeling in stomach. Weariness of limbs, spasmodic twitching in muscles of calf; stool delayed for some hours; emission of very fetid flatus. Sadness, loss of power of thinking, incapacity for mental work; then general prostration. From 5 to 7:30 p. m. pretty free from these symptoms; then the confusion of forehead returned, with general weak feeling lasting till 9 p. m. Next day same symptoms but slighter. (Ibid., 60.)
28. Dr. STERN, aet 36, accustomed to have 2 stools daily, one early, the second after a meal. The dilutions from 30th to Ist caused no symptoms. – May 25th. 5 dr. tinct, no stool. – 27th, 7 a. m., 8 dr. No stool. – 29th, 7 a. m., 10 dr. No stool. Confusion of head. Breathing laboured as if thoracic muscles were relaxed. After breakfast a second stool, and 1 hours later a third liquid stool. – 31st, 7 a. m., 15 dr. After 1 hours vision veiled, head confused as after drinking alcohol. Constipation, emission of flatus. From 5 to 7 p. m. dull pain in occiput, tearing and drawing in forearms. – June Ist, 7 a. m., 15 dr. Depressed spirits, dislike to work constipation. – 3rd, 7 a. m., 20 dr. 9 a. m., vision dim. 11 a. m., feeling of discomfort, emptiness and sinking in stomach, accumulation of water in mouth, frequent spitting, inclination to vomit, exhaustion, trembling of hands and feet, transient jerkings in hands, cold sweat on forehead, confusion of head, heaviness jerkings in hands, cold sweat on forehead, confusion of head, heaviness in eyes. This lasted till noon. Cold air revives momentarily. Complete anorexia, loathes food. After a cup of coffee these symptoms went off. (Ibid., 63.)
29. a. Dr. A. v. SZONTAGH, aet. 27. Dilutions from 30 to 5 caused no symptoms. – July 6th, noon, 5 dr. tinct. No effect. – 8th, noon, 8 dr. In afternoon and next m. pressive pains in rectum like haemorrhoidal congestion, increased by touch. – 11th. 10 dr., no effect. – 13th. 15 dr., immediately pulse rose 14 beats higher, slight burning in ears, weakness of knees and prostration of whole body, nausea relieved by eructation. All this lasted 1 1/2 hours, but on eating there was a kind of spasm of oesophagus which made even water difficult to swallow. – 16th. 15 dr. next m., at the normal time a stool, at first hard and difficult, at the end diarrhoeic. – 11th. Was wakened at 5 a. m. by call to stool; he had a copious, pappy, dark – coloured, almost inodorous stool. Pulse 90, roaring in ears for 8 m. Soon afterwards a second diarrhoeic stool. evening, on extensor side of left thigh 2 itching wheals the size of peas, which went off after some day – 19th, noon, 20 dr. Soon eructation, weakness in arms and legs, sleepiness; when eating, every time he swallowed, spasm in oesophagus, after meal discharge of much flatus. A kind of urinary tenesmus; at the commencement of micturition had always to wait some time on account of spasm of the sphincter vesical, but when the urine came it was in full uninterrupted stream. This occurred every time he urinated. Frequent erections at n. in sleep. – 21st, noon, 25 dr. After airing, much flatus, evening, roaring in ears for some m. Next day pulse quickened by 10 beats, roaring in ears, heat and sweat for 10 m. After falling asleep in., a sudden jerk through whole body that woke him up. – 23rd, noon, 30 dr. Soon great weariness in legs, increased secretion of urine. After 1 1/2 hours hurry in doing things, thinking, too, was rapidly performed, but its quality was unaltered. – 25th. While sitting roaring in ears for 20 m. – 28th, 35 dr., and 30th, 40 dr. Besides prostration and emission of flatus, no symptoms.
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.