b. Injected mxl by two punctures, one on either side of body. From 7th to 10th m. vomiting, until stomach was emptied. At 15th m. lay down and remained quiet, with eyes open; pulse 130, regular; respiration shallow, irregular. During next 1/2 hours, respiration was much disturbed, and occasionally suspended for 15 seconds; after a long drawn inspiration, it gradually became slower, and ultimately sank to 15; the pulse meanwhile was depressed to 72, and influenced by the breathings. Glairy mucus continued to trickle from the mouth. Up to end of 3rd hours she did not have any sound or continuous sleep; she remained dull and quiet, and when called, or disturbed by the approach of anyone, would get up and walk slowly into the next room. When left undisturbed she fell off into a nap, from which a slight noise awoke her. After 3 1/4 hours the somnolency had almost entirely passed off, and she was walking about most of the time. She could run, and jumped well off a chair. Pulse 80, respiratory. Resp. 15, irregular. Pupils contracted to 1/6 at diffuse daylight, and dilated widely towards dusky side of room. (HARLEY, op. cit., p. 109.).
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.