b. P – also took 3 dr. of tinct. in 1/2 oz. water. After 1 hours lassitude and inclination to sleep came on accompanied by quicker and weaker pulse; both symptoms disappearing within 1 h. Had little appetite for midday meal. On repeating same dose lassitude and weariness lasted 2 h. On taking 6 dr., besides lassitude and somnolence, felt heaviness of whole head, pressure in forehead, and smaller pulse, lasting 2 hours (Ibid.)
11. SIEBENHAAR, 1 hours after 5 dr., felt same heaviness in head, with feeling as if head had been hanging down for a long time, lasting barely 1 h. Then took 6 dr. After 1 hours was surprised by feeling of pressure in region of stomach, followed shortly by heaviness and confusion of head lasting 15 m. Pulse meanwhile was quicker and smaller than usual. After 7 dr. same symptoms occurred, but lasted nearly 2 h. Appetite for dinner diminished. After eating this and going into street, was seized with such severe nausea that he with difficulty refrained from vomiting; this nausea continued for 10 m. and then gradually disappeared, and was accompanied by an extraordinary feeling of lassitude and weariness, lasting whole day and associated with inclination to sleep. During following n. was very restless; at 2 a. m., on getting out of bed, was seized suddenly with giddiness and nausea, so that he had to lie down again. This condition lasted 15 m., after which he fell asleep again. Felt some headache on awaking next m. Next day took 8 dr.; after 1/2 hours felt troublesome pressing and cutting pain in region of stomach and deeper in abdomen, lasting about 3/4 hours; with this there was confusion of head, especially in frontal and parietal regions, changing to actual pain, which lasted several h. Pulse meanwhile was slower and weaker than usual. During latter part of day there was uninterrupted lassitude, weariness, and distaste for mental or bodily exertion. Next m. felt unrefreshed. Similar effects followed dose of 9 dr. except that he felt sleepy, and weariness and lassitude lasted all d. Pulse was unaffected.
b. February 4th, at 9 a. m., took 1/4 gr. of Opium At 10 a. m. an attack of giddiness and confusion of head, changing at times to lassitude and indifference to everything around; pulse meanwhile was several beats quicker but weaker than usual. These symptoms lasted about 1 h. Similar symptoms followed dose of 1/2 gr. with addition constipation. On 9th, at 9 a. m., took 1 gr.; towards 11 felt pain in abdomen more pressing than cutting in character, especially in umbilical region, spreading thence over whole abdomen, which appeared somewhat distended, increasing in intensity till noon, and disappearing at 1 p. m. During afternoon and evening felt more tired and weary than usual. Faeces next m. were hard. Similar effects followed dose of 1 1/2 gr., with headache during evening in addition. Next took 2 gr.; after 1 hours abdominal pain came on. and lasted 5 hours, leaving feeling of weariness, lassitude, and indifference behind. Zest for food was all day less than usual. Bowels only acted on m. of third day, faeces being hard. (Ibid.)
12. JORG, on August 15th, at 8 a. m., took 1/6 gr.; at 9 a. m. slight confusion spread over head almost imperceptibly, increasing about 10 to feeling of complete intoxication, and accompanied with giddiness, vanishing again about 11. From this time till evening felt frequent pressing in eyes, with diminished secretion of mucus, and mistiness of sight; constant feeling of dust in one or other eye, with itching and burning in same; at time felt as if accumulated mucus obstructed sight, eyelids were, however, rather dry. This condition of eyes passed off at dusk, but recurred during next 3 day if exposed to bright light. On intestinal canal, drug produced following effects: – At 9:30 a. m. cutting in abdomen came on, and soon after great urging to stool, which he could not resist; small hard motion was passed, but without relief, for cutting pain lasted till 1 p. m., nausea being present between 11 and 12. After 3 p. m. was troubled with pressing pain, sometimes in vertex, at others in occiput, spreading later towards nape of neck, and becoming at times boring in character, lasting till bedtime and only disappearing during n. after several hours of very disturbed sleep. Similar effects upon brain and intestinal canal followed dose of 1/4 gr. In addition to this, after 1 hours pulse beat 8 to 10 times in m. quicker than normal, was contracted and hard; after 4 hours it became full, and towards evening gradually returned to its normal condition. From 2 to 4th. after dose felt pressing and stabbing in thorax, especially towards posterior wall, and at times as if to spinal muscles. Occasionally slight cough was present. Skin became generally warmer, – face being hot, and sweating considerably from 9:30 till noon; complexion during this time changed several times from dark red to pale red, former being most prominent, especially on cheeks. During afternoon and evening bowels were constipated, and abdomen distended; during sleep was much disturbed; awoke next m. tired and unrefreshed, and suffered from characteristic headache from 9 a. m. till noon, with some cutting pain in abdomen.
b. Took 1 dr. of tinct. After 1 hours felt pressure in forehead and over eyes, but not painful; coupled with this was a tremulous drawing in scalp covering forehead and parietal region, lasting 1/2 hours; gradually pressure in forehead and over eyes changed to heaviness and inclination to sleep; felt all day as if he had not slept enough. On Aug. 7th, at 8 a. m., took 2 dr. After 25 m. was attacked by pressing pain in both frontal eminences, descending to nose, and apparently affecting especially (both) nasal bones; 1 hours later this pain passed off, but left behind pressure in forehead, especially over eyes, and general heaviness of head. With first appearance of pain increased heat suddenly spread over whole body, soon succeeded by outbreak of general perspiration and feeling of increased vascular action. Pulse – best 10 above normal, large and hard; fulness and hardness ceased at 10:30, and acceleration between 3 and 4 p. m.; perspiration ceased between 11 and 12 a. m. Besides these effects of drug, at 9:30 felt pressing pain between tip of right shoulder – blade and posterior wall of thorax; pressing pain kept meanwhile coming and going left frontal eminence. At same time eyes became dry and weak with feeling of dust in them lasting till bedtime. From 5 till 10 p. m. slight pressing headache, especially in left half of vertex and forehead, alternated with pains in spinal muscles, at times extending into thorax. Bowels were sluggish. On 9th, at 8 a. m., took 3 dr. After 15 m. felt general oppression of head, passing on 15 m. later to confusion, almost amounting to giddiness, rendering thinking and speaking difficult. At same time there came sudden heat over whole body, especially about head, where abundant sweat broke out. Pulse was contracted and rather hard, beating 10 above normal. At 11 a. m. the contraction passed off, and during p. m. circulation became normal. Confusion of head became less after 9 a. m., then came somewhat sensitive cutting in region of navel, soon accompanied with urging to stool. Cutting pain lasted I hours, and was accompanied by recurring pressing in thorax, causing and relieved by slight cough. Almost at same time for 15 m. there was feeling of thrusting from thorax and spine towards nape of neck, and as if muscles and vessels there were being squeezed together. Upon this followed at times recurrent stabbing, apparently spreading from within the thorax outwards, and especially to region of right shoulder – blade. From 10, mouth and gullet became somewhat dry. During p. m. slight confusion of head continued, combined with two slight attacks of pressing pain on right side of vertex and forehead, lasting each time about 20 m. From noon till evening abdomen was distended; neither flatus nor faeces passed until 10 p. m., when after great straining in small stool, not hard, was passed. From noon till 6 p. m. felt heaviness, lassitude, and distaste for work; after 6 these symptoms changed to somnolence. N. was restless; sweated much and passed much foul – smelling flatus. Next day felt “out of sorts,” and for 3 day was troubled with same pressing headache as after 2 drops. This pain in head and nose appeared as if fixed in periosteum. (Ibid.)
13. a. EDWARD JORG took 1 dr. on Aug. 10th at 8 a. m. After a few m. felt buzzing in head soon followed by confusion, and cutting pains in abdomen lasting till 9:30, recurring at 10:30, and lasting 1/2 h. After 9:30 confusion changed into true pressing headache, attacking forehead more especially, and descending towards eyes and nose, ending between 11 and 12, and leaving behind general weariness and lassitude. Next day at same hour took 2 dr. After few m. smart cutting in region of stomach and umbilicus came on, and after 15 m. pressing and confusion spreading over whole head, but especially towards vertex. All these symptoms vanished about 10 a. m.; then eyes began to burn and feel as if there were sand or dust in them. At same time considerable heat of whole body came on, but more especially of head; skin generally quickly began to sweat, and congestion of head showed itself; then head became really painful, especially in frontal region. Pulse beat was 10 above normal, full and hard. Eyes were better towards noon, but other symptoms lasted until well on in afternoon, also accompanied with lassitude and general weariness. During p. m. and evening headache became at times very troublesome, spreading from vertex towards right orbit, and apparently pressing from within outwards. At 10 p. m., on going to bed, heat and headache prevented his sleeping; later on slept quietly; next m. head confused and dull and abdomen heavy, but these symptoms gradually passed off during forenoon. Morning stool was abundant.
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.