7e. 2nd dec. trit. -2nd, 6 a. m., 90 gr. The shooting chest pains were no longer present in the m., but the pressure under sternum and the feeling of rawness and soreness were. 9 a. m., whilst driving pressive frontal pain with vertigo, stupefaction, heat in head as though he had been passing the n. in drinking. Ill-humour, crossness; for some day past complete absence of sexual desire. 10 a. m., whilst driving the drawing in right thigh returns, as also the pain in shoulder, but not so badly as yesterday. Burning in esophagus when swallowing, slight griping in belly. 5 p. m., when taking a walk has such weariness and prostration that he fears not to be at the appointed place in time, almost at same time dislocative pain of right big toe, making it difficult for him to tread. 8:30 p. m., pressive frontal pain, especially on left side; now and then extremely painful stitches and rends in left elbow-joint increased by extending the arm; similar stitches and rends in left shoulder- joint; heaviness and burning of left upper eyelid, heaviness of hands, flying stitches in left side of chest and left knee-joint. Sudden pain from left shoulder-joint along ulna to wrist, it gets to such a height that the affected part becomes extremely sensitive. When walking tensive pain in back of left thigh for 2 or 3 m. Suddenly in 1st phalanx of middle finger pricks as with a fine needle. 10 p. m., the pain in shoulder-and elbow-joints becomes intolerable and compels him to go to bed. In bed transient stitches in left ankle-joint, toes both elbows, nape. N. very restless, full of gruesome, frightful dreams. 4 a. m., woke with bruised and heavy feeling in all limbs, tearing in left elbow-joint and right shoulder, pressive frontal headache alternating with shooting, sudden stitches in 3rd phalanx of left index, griping in bowels, cross humour and disinclination for all employment. 3rd, 6 a. m., same dose. Some pains in belly, which together with the stitches and rends in left shoulder and left elbow-joint and wrist, last all day 6 p. m., increased pressure under sternum, chilliness all over body, prostration with weariness. N. restless, with frightful, anxious dreams. -4th. Woke with feeling of weariness and powerlessness. 9 a. m., 90 gr. Pains in belly, frequent yawning, increased secretion from sublingual gland; a soft pappy stool with feeling of tenesmus and forcing in rectum thereafter as in dysentery. Burning in esophagus with empty eructation. Tension and pressure under sternum compelling frequent deep breathing. 9 a. m., when writing tearing in left elbow-joint, violent pains in belly. 11 a. m., when walking pressure and heaviness under sternum, transient shooting frontal pain, excessive heaviness and weariness of legs, they can scarcely bear him. A.m., urinated 3 or 4 times copiously. Noon, after eating veal, pressure in stomach and heaviness in belly. From 1 to 5 p. m., when riding pressing headache from crown to left temple. Sudden exhaustion and prostration, inclination to sleep so that he can hardly keep awake on his horse. On walking down a hill sudden shooting pain in left knee-joint, lasting 4 or 5 m., which hindered him much in walking. Whilst writing sudden penetrating stitches in left shoulder-joint and left elbow-joint, whence the pain spread on the inner surface of the forearm to the fingers. Throbbing frontal pain, with heat and redness of face, sudden stitches in right wrist, so that he cannot write, -all these pains came suddenly, lasted 4 or 5 m., and went off just as suddenly. Pressure and heaviness as of a weight on chest, making him breathe deeply. During supper violent tearing-shooting pain in second joint of right thumb, then leaving this part suddenly, in left shoulder, then the left elbow-joint, then again in right thumb-joint, left knee, left side of chest in region of 6th rib- all suddenly and all within 1/4 h. The left shoulder, left elbow, and right hand are painful till 9 p. m. 10 p. m., when going downstairs sudden shooting-tearing pain in second joint of right big toe. In bed drawing in left shoulder. N. very restless, full of gruesome dreams. 6 a. m., pain in right big toe. -5th, 6 a. m., same dose. After 2 hours shooting pains to left of sternum in region of 4th rib; pressive pain with feeling of tightness under sternum, which soon increases to real dyspnoea. Pain in stomach and bowels, 2 greenish loose stools. 9 a. m., transient drawing pain in both shoulders and left elbow-joint. Pressive pain in forehead and heat of head. After urinating burning along urethra for a m., great heaviness in right forearm, making writing difficult. 11 a. m., obtuse stitches in l, side near sternum, great oppression of chest, increased by deep inspiration. 2 p. m., whilst walking great weariness and heaviness of feet, dyspnoea. 5 p. m., tearing and drawing in left ankle-joint, pain in belly, great dryness of nose. 7 p. m., tearing in left wrist- joint for 2 or 3 m. Extremely painful jerking tearing in second joint or right thumb; sudden shooting in right side near edge of sternum. Between 7 and 1 p. m. constant wandering pains (tearing and shooting), alternately in right and left shoulder, both elbows and wrists, fingers, left knee, right big toe, right and left side of chest, always only for a few m. in same place. N. quiet. M., woke with bellyache. -6th, 6 a. m., same dose. Immediately increased pain in belly and great flow of water into mouth. After ordinary stool feeling of shooting along rectum, with urging and tenesmus. Heaviness and pressure in chest; transient stitches, alternately on right and left of sternum, great weakness and prostration, difficulty of walking. Pricking and tearing in skin of whole body, sometimes more violent at one place than at another, must rub himself with his clothes, with heat all over the body, feeling of formication and as if hair of head was gently drawn up, whilst walking in open air, lasting 1/2 hours 11 a. m., throbbing frontal pain, with heat in head; feels very uncomfortable, appetite diminished. After a scanty meal pressure and fulness in abdomen. The heaviness, pressure, and tightness of chest, as also the dryness of nose, last till n. – 7th. Woke from restless sleep with pressive headache and some griping in belly. Took same dose. After 1 hours he had the occasional transient shootings in left chest, then heaviness and pressure under sternum; to these were added dazedness of head, formication all over body, with burning and itching. 1 p. m., whilst standing speaking violent vertigo, with stupefaction, so that his senses seem to leave him and he is in danger of tumbling forwards. 3 p. m., pain in right wrist-joint (transient, shooting and tearing). On back of right thigh cramp, with sensation while walking as if sinews were too short, which makes walking uphill very painful. Great exhaustion during a long walk. N. restless, disturbed by heavy anxious dreams.
7f. 1st dec. trit. -8th, at 8 a. m., 90 gr. Soon heat in face, confusion of head, shooting and tearing, now in left, now in right shoulder, suddenly in right knee, in right wrist-joint. 11 a. m., obtuse stitches in left side of chest, pressure and weight under sternum, dyspnoea, great exhaustion, dryness of nose. Noon, vertigo, thinks he must fall forwards. Great irritability of temper, restless sleep. M., heaviness heat, and dazedness of head. -9th, 5:30 a. m., same dose. After 1/4 hours transient stitches near sternum, pressure in chest. 11 a. m., tearing in left wrist and left shoulder. P. m., flatulent pain in abdomen, cramp in right thigh. Dyspnoea all day, great dryness of nose. Restless n., with heavy dreams. -10th, 10 a. m., same dose. Same symptoms in same order as yesterday. To-day it strikes him that for the last 10 day the inner surface of the nose has been ulcerated and covered with scab, which when removed soon re- forms. Inflammation of prepuce, with redness. (An intolerable itching and smarting of scrotum, with erysipelatous inflammation of the skin, which had tormented him for a month, has disappeared these last 8 day -it did not reappear.) 8 p. m., very painful pressure on chest, heat in face. N. very restless, full of anxious dreams. M., woke with confusion of head and great pressure on chest, relieved by expectoration of consistent purulent phlegm. -11th, 6 a. m., same dose. Immediately pain in abdomen, pressure under sternum. Sudden dislocative pain in right big toe, hardly allowing him to tread. Transient stitches for 2 or 3 m. on left side of chest near sternum. Noon, near inner border of scapula frequent stabs as with a pointed knife, which take away the breath, for 1 h. Drawing pain in left inguinal region. Tearing in left knee and right wrist. 2 p. m., violent painful tearing in right frontal and supra-orbital protuberances, with heat there in which the eye participates for 2 or 3 m., pain about navel. Drawing in left thigh, pressure on chest under sternum. evening, unusual appetite, saliva much increased. 10 p. m., violent tearing-throbbing pain in right frontal and supra- orbital protuberances for 3 or 4 m. Tearing in left upper arm and right wrist. Traces of a thin yellow discharge from urethra. – 12th, m., pressure on chest, expectoration of thick yellow phlegm from lungs. Heaviness of head. (Ibid., 341.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.