7a. EMIL KOLLER, surgeon, aet. 35, in good health, took March 15th m., 20 gr. 6th dec. trit. Immediately, comfortable feeling in stomach, followed in 1/4 hours by flow of water into mouth, which gradually increased, and seemed to come from submaxillary glands. After 2 hours tension in these glands, which are sensitive to touch. P. m., feeling of tension under sternum, heat of head (especially forehead) and face, occasional feeling of rigor, which came from head and spread all over body on coming into room after driving for some hours, and then whilst driving. Increased secretion of saliva all d. In evening his neck cloth seemed to press on the sensitive submaxillary glands. In bed, drawing pain on inner surface of upper arm for 1/2 h. Very restless n. On passing urine at 2 a. m., burning along urethra lasting 1/4 hours -14th. Same dose, m. Increased saliva still present, tenderness of submaxillary glands increased, so that he cannot bear his ordinary neck cloth, its pressure increases the secretion and causes pressure and tension in the gland. Pain as of dislocation in shoulder-joint, great weakness and weariness of arms, especially right, he can with difficulty hold a book in his hand. Heaviness of hand when writing, feeling of gone to sleep of forearm on resting it on writing, table. Whilst reading, a peculiar sensation of burning under lower third of sternum; nausea, feeling of emptiness and inclination to vomit for 3 or 4 m. Noon, feeling of horripilation spreading from crown to chest and arms, with sensation as if all the hairs of the head were gently drawn upwards. Remarkable weakness of feet when walking upstairs. evening, very drowsy, so that he could not read as usual in bed. -15th. 30 gr., m. After 1 hours confusion of head, increase of saliva from sublingual gland, feeling of burning long esophagus to stomach, lasting 2 h. During day great weakness of arms and legs. evening, greatly disposed for mental work. Restless sleep with anxious dreams, frequent waking. -16th. 60 gr., m. After 2h., whilst walking, burning in stomach which extends to pharynx. Almost simultaneously griping about navel, with increased call to stool. During day 3 loose, green, very ill-smelling stools. P. m., during a ride of 2 hours violent griping about navel, pressive frontal pain, shooting in left frontal protuberance lasting 3/4 h. evening, griping continues. N., restless sleep disturbed by anxious dreams, such as tumbling down a height from horseback. 4 a. m., pain in belly, ineffectual urging to stool, a disagreeable prickling sensation along the urethra. -17th, m. Discharge of extremely foetid flatus with relief, 2 greenish loose stools of very bad smell. Weakness of arms, general prostration, griping in belly, increased saliva. 9 a. m., 90 gr. Immediately pain in belly, especially in seat of transverse colon. After 1 hours urging to stool (4 times to-day), which was of the same diarrhoeic character. During a walk of 2 hours griping in region of transverse colon lasting till n., dyspnoea, feeling of rawness under sternum, palpitation of heart, frequent flying stitches on left side of chest in region of fifth rib, feeling as if anterior surface of lung were swollen. 11 a. m., heat in forehead, legs and sacrum as if beaten; on walking rather quickly downhill sudden dislocative pain in left hip- joint, so that for 5 m. he cannot stand on that leg. Noon, good appetite. After a small piece of roast lamb fulness in stomach, distension of abdomen, sudden satiety, great thirst, disinclination for mental work, apathy. Heaviness of arms, and especially of legs, so that he cannot play the piano. N. quieter but full of dreams. Urine turbid as if mixed with brickdust. M., violent bellyache, which prevents him taking breakfast.
7b. 5th dec. trit. -18th, 9 a. m., 60 gr. After 1/2 hours nausea, constant yawning, griping in bowels, dazedness in head, crossness, ill humour, drawing-tearing pain in left supra-orbital ridge, transient shoots over left knee-joint, disinclination for mental work. 11 a. m., frontal pain, increase of saliva. After dinner flatulent distension, burning pain in stomach, increase of saliva, which has a metallic taste, burning pain in umbilical region, eructation of what has been eaten at dinner, heartburn, frequent yawning. evening, heat and redness of face. N., restless, frequent waking. M., weak, with bellyache. -19th, 9 a. m., same dose. After 1 hours frequent urging to urinate, heat of face, increase of saliva, griping in bowels. After a very moderate meal pressure and feeling of fulness in stomach, eructation of food, pain in belly. During a ride of some hours at 2 p. m. drowsiness, so that he can with difficulty keep awake on his horse. On getting off and walking great weariness and bruised feeling, especially in thighs from sacrum. Frequent urging to urinate, dislocation pain in left knee-joint whilst walking, the pain in belly lasts all day and even in bed. -20th, 6 a. m., 90 gr. Immediately rush of saliva into mouth (the tenderness of submaxillary gland has gone the last 2 d.). After 1/2 hours pain in stomach and region of duodenum, heat in head, griping in bowels, great prostration of arms and legs, pressure under sternum. 9 a. m., after usual breakfast pains in body worse. evening, throbbing pain in left frontal protuberance and supraorbital ridge, crossness, great irritability. -21st, 6 a. m., same dose. After 1/2 hours increased saliva, of metallic taste. 9 a. m., burning, extending from stomach to pharynx, eructations, griping in bowels, cheerful humour. 11 a. m., sudden, extremely violent shooting pains in left big toe in jerks, as though it were torn out, whilst walking in room for 5 m. From 7 to 10 p. m. pains in belly.
7c. 4th dec. trit. -22nd, 10 a. m., 90 gr. Between 8 and 9 a. m. pains in belly, rush of water into mouth, rumbling and gurgling in belly, so bad while walking he thought it was someone behind him, lasted 1/2 h. After dinner burning like fire in stomach up to pharynx, eructation of food, metallic taste, sensitiveness of stomach, pain in belly as after a chill, tensive and full feeling in stomach and hypochondria. 7 p. m., whilst eating got such a violent pain in metacarpal bone of right middle finger that he almost dropped his spoon. After supper increased pain in belly. -23rd, 6 a. m., same dose. After 5 m. drawing pains from left shoulder to hand, sometimes in jerks like electric shocks. After 1/2 hours loud rumbling and gurgling in belly, which is distended; confused head; during a walk of 1 1/2 hours very painful flatulent colic, painful distension of whole belly, eructations, rare discharge of flatus with relief, no stool (has usually 2 every m.) Transient stitches in left frontal protuberance, crossness, prostration. During a drive from 10 to 12 a. m. the violent pain in belly goes off, but an extremely tensive feeling of fulness and distension remains. After a very moderate meal the griping in bowels, and particularly the pain in stomach, recur with violence, and do not leave him during a drive of 4 h. He feels very ill, with great irritability of temper, every trifle makes him angry. N., quiet sleep but frequent waking. 4 a. m., pappy, clayey taste, burning of tongue as after smoking strong tobacco (he has not smoked for 3 or 4 day, having lost all taste for it), pressive headache, loathing at all food (has eaten nothing since yesterday). -24th, 10 a. m., same dose. 9 a. m., the first stool for 2 day, it was firm, and was passed with much pressing, and accompanied by burning-like pain from anus up rectum. 10 a. m., violent griping in bowels, lasting all d. N., heavy, anxious dreams. Woke in m. with bad taste, tongue thick, burning as after smoking strong tobacco, no appetite for coffee, great dryness of nose, which is completely stopped up. Confused head, crossness. -25th, 6 a. m., same dose. Soon some nausea. A.m., griping in belly, flatulence, increased saliva. N., bad dreams. M., tongue furred.
7d. 3rd dec. trit. -26th, 90 gr. Noon, sudden shooting- tearing pains in right supra-orbital ridge for 5 m., urinates 4 times in 2 h. P. m., when walking, violent pain in belly. -27th. Had to go a long journey, so had no med. M., griping in bowels. 7 p. m., tearing in both shoulder-joints for 1/4 h. N., restless sleep, full of horrible dreams of murder, poisoning, & c. M., tiresome dryness of nose. -28th, 6 a. m., same dose as on 26th. Pain in belly lasts all day, rush of water into mouth. 5 p. m., chilliness all over body, disinclination for mental work, great drowsiness, increased pain in belly. N., very restless, sleep as if stupefied, full of horrible dreams. 6 a. m., awoke with pressive pain in forehead, nasty taste, griping in bowels, distaste for all food, even coffee. After 1/2 hours, urging to stool, purging with gripes. Sore pain under sternum, dyspnoea, great prostration, heaviness and weariness of limbs, so that he dreads riding, and prefers doing his business on foot. Feeling as if he had been sitting up all n., crossness, great rush of water into mouth, such dryness of nose that for 10 day past he has not required a pocket-handkerchief. 8 a. m., whilst walking shudder all over body, skin-spasm, griping in belly, diarrhoea, soreness and pressure under sternum, crossness, ill humour. -29th, 10 a. m., same dose. Increased saliva, griping internally, lasting all day, tensive dryness of nose. P. m., sudden violent tearing pain in second joint of big toe, lasting 5 m. After 5 m. more, tearing pain in right knee-joint. 6 p. m., rigor all over body for 1/2 hours, coldness of feet in warm room, unconscious drowsiness, cannot keep awake; goes to bed at 8:30 p. m., and the sleep is full of anxious dreams. -30th, 9 a. m., same dose. Immediately griping in bowels, lasting all d. Between 6 and 7 p. m., rigor all over body, even in warm room, great thirst. N., restless sleep with anxious dreams. M., great prostration, weariness of feet, compression of head, pressure under sternum. -31st. No med. During day griping in belly and great weakness of all limbs. – April 1st, 6 a. m., 90 gr. Pains in belly. Noon, suddenly an extremely violent dislocative pain in left shoulder, so that he could hardly guide his horse; after lasting 1/4 hours the pain left this part, but came on suddenly in right shoulder-joint, where it remained for some time. After 1 hours the left knee- joint became very painful (tearing-drawing). Great weakness and prostration of whole body, especially hands and feet. 3 p. m., throbbing frontal pain, ill humour, mental and bodily prostration; he feels very ill, cannot study or think, with great forgetfulness and absence of mind. Whilst writing, dislocative pain in right wrist, so that he must often lay down his pen. Tension under sternum as if all were too tight, with same feeling in chest. Extreme dryness of nose. 4 p. m., such weakness of legs it requires a great effort to keep himself on them, while standing they knuckle under him. The pressure and heaviness on chest increase, and compel him to breathe deeply often, which gives him some relief. Shooting in region of fifth rib close to edge of sternum when at rest. After 1/2 hours the same shooting in left side, drawing-tearing pain in 3rd phalanx of left index lasting 1 to 2 m., cramp in calves, aggravated by walking and extending foot, relieved by rest. 6 p. m., shooting pain in both frontal eminences, alternating with throbbing; for 1/4 hours increased salivary secretion. 9 p. m., great mental and bodily prostration, excessive ill humour, chilliness all over body. In bed at 9:30 p. m., drawing-tearing pain from hips to feet on both sides exactly in course of sciatic nerve, lasting 15 m. Sudden pain in right fingers, tearing as if fingers were torn out for 5 m. The shooting in both sides of chest, as also the pressure under sternum, is still there, the latter very painful. The pain in shoulder goes off gradually in bed. N. restless, full of gruesome, anxious dreams.
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.