“The last prover had an initial blood count of 5,100,000 red cells and 8,200 white cells and a final count of 4,200,000 red cells and 11,600 leukocytes. This prover, also a female, was given the 30x. Shortly after commencing the proving she complained about a sour taste in the mouth, gastric disturbances, nausea, loss of appetite, regurgitation and a constant inclination to vomit. There was great restlessness day and night, and sleep was often interrupted.
After 10 days the prover began to develop peculiar symptoms in the eyes. Her vision became very poor, especially on the right side, objects were blurred and wavered; the eyes began to ache and vision of the right eye was at times absent. Inspection showed the pupils to be extremely dilated, the right more than the left, the eyeballs being very sensitive to touch. The right pupil did not react to daylight and only slightly to artificial light. The left pupil reacted somewhat better. This condition remained uncharged for about 5 days, and then gradually and slowly cleared up. It came back, however, to a lesser degree, for a period of about 4 days and then disappeared.
“The most striking fact in the proving of benzol seems to be the influence it had on the circulatory system. It caused a slowing of the blood stream which in the guinea – pigs brought about the formation of infarcts. In the human provers it resulted in a decrease of the red and in an increase of the white cells in general”.