13b. Dec. 8th. – Took 15 gr. of the raw material. 9th and 10th. – Took 3 drachms of same. 8th and 9th. – No symptoms. 10th. – Frequent micturition after dinner; stool loose, with tenesmus; thereupon shooting in rectum. 11th. – evening, 4 drachms. 5 m. after taking the above frequent yawning, recurring every m., which up till 9 o’clock became much more violent and ultimately spasmodic. After drinking wine it ceased. During the yawning constant nausea; weakness of hands; itching over whole head; fine stitches in different parts of body; frequent shuddering over body; pale complexion and lips; loss of appetite. Food has no taste whatever. After drinking wine several times taste returned, and appetite also was aroused; only there remained still great weakness and sleepiness, so that he was obliged to go earlier to bed than usual. 12th. – in m. hoarseness, with out pain. 11 a. m., fine painful shoots through tip of right thumb; in second phalanx of thumb pain as if dislocated. Distraction while conversing. 13th and 14th. – In evening, about 7 p. m, 3 drachms. 15th. – Took same dose about 10 a. m. A few m. after that nausea and vomiting, with dryness in mouth and burning feeling in stomach; loathing of food;; very great thirst for wine; after wine more appetite. After dinner call to stool; the latter was consistent. 11 p. m., again 3 drachms. Soon after, fine shoots in various places in body, rapidly passing off; shouting in sleep. 16th. – Frequent urination whole d. Urine pale, clear. 6 p. m., 4 drachms. 5 m. after yawned 8 times at short intervals; then accumulation of water in mouth and spitting of same; after that hiccough, alternately with yawning; ultimately hiccough only, lasting 1/4 hour; all this time nausea and inclination to vomit, with total relaxation and weakness of body; contraction of skin in vertex; in left half of forehead pressive pain; some hours after, great dryness of mouth; uneasiness in whole body, which allows no rest anywhere. he was morose, went to the theatre, but was obliged immediately to come out again on account of inquietude and discomfort; Thereupon great weakness, particularly in legs. Desire for wine; he could scarcely wait till it was brought to him in the hotel; in a few m. he drank a pint with two pints of water. |Unquenchable thirst; loss of appetite; loathing of animal and other food; avidity for bread. He ate four small loaves of white bread, with constant drinking and involuntary movement of mucus of mastication, and great appetite. Distension and swelling of abdomen, which prevented further eating. He still had good appetite, but only for bread, after which great sleepiness. He slept soundly. He was awakened about 1 a. m. On awaking, pappy taste in mouth, m with much thirst. he drank 2 glasses of water, went out, came back, and slept quietly till m. 17th. – Frequent micturition whole day, especially after dinner. After dinner, ion sitting, cramp pain in left index and thumb (first phalanx), particularly if he leaned arm upon anything; soon after that same pain in right thumb; weakness of hands. He was quite unable on account of weakness to play on the piano. Stool small, although there was feeling as if he should have an abundant one; shoots in skin in different parts of the body; frequent emission of flatus, offensive in m. but not after dinner; pale lips; dissolute look. Tobacco is distasteful. 18th. – After supper obtuse shoots in right hand, especially in thumb and index. He could not keep hand still; it removed involuntarily as in chorea, at same time it was so weak that he was usable to hold cards in playing. Stool insufficient. 19th. – 10 a. m., burning shooting in anus and feeling as if it were raw, especially in walking. In evening he could scarcely sit on account of painful protruding piles. 11 p. m., 3 drachms. In bed yawning, hiccough, nausea; late falling asleep, early waking. On awaking right leg was weak, as if he could not raise it, from knee downwards particularly. 20th, 5 p. m., tickling in larynx and short dry cough. Weakness during whole d. Was awakened towards 2 a. m. Whilst awaking, cough from tickling in larynx. Each time he expectorated a considerable quantity of frothy saliva. The inclination to cough was increased by lying on back. yawning alternately. with coughing. 4 p. m., cutting in abdomen, quickly passing off, with urging to stool, as if looseness would come on; however, there came only 2 consistent lumps; after that tenesmus; dull shoots below right nipple, likewise in belly to right of navel; squeezing pain in second phalanx of left thumb. About 6 a. m. all the symptoms cased, and he slept on quietly. 21st. – 11 p. m., great inquietude in legs, beginning at knees, which would not allow him to sit. he was compelled to rise and walk about, on which the uneasiness always went off. 22nd. – Made a journey into the country. About 6 p. m. in the carriage frequent fits of yawning one after another, Thereupon hiccough six times; tickling in throat, which provoked coughing; dry cough for an hours 11 p. m., heat and uneasiness in legs, which scarcely allowed him to remain in the carriage. As soon as he arrived at the end of his journey the uneasiness and heat also ceased. 23rd. – On the road home, throughout whole forenoon, nausea, frequent inclination to vomit; loathing of tobacco, wine, and beer; absence of appetite. Not until following day at dinner did appetite return. The frequent emission of urine and flatus ceased after a few day,; there only remained a disinclination to tobacco smoking. The loathing of the medicine was so great that he could not think of salt without feeling sick. Dislike to society. 31st. – before going to bed at n. took 4 drachms. Directly after, inclination to vomit; repeated yawning; compression of the scalp and of the head, beginning at the temples; pressive feeling from stomach upwards into pharynx. Awoke at 5 a. m. quite lively with much thirst. Jan. 1st, 1844. – In forenoon emission of flatus, with feeling as if soft stool would follow. After dinner, urging to urinate, with frequent emission. before going to bed again, 4 drachms. At 5 a. m. awoke in a good humour. 2nd. – forenoon, much emission of flatus. After dinner frequent micturition. When he puts his hands into his coat pockets, prickling with painful feeling as if asleep in hands (during whole d.). 11 p. m., uneasiness in the lower limbs which will not allow him to sit, especially strong when laying the hands on a hard body; cramp – like pain in right thumb. 3rd. – Before going to bed 3 drachms. Awoke at 5 a. m. perfectly refreshed. In riding in a carriage into the country, each time he exposed his nose to the open air much watery secretion of mucus, now in right, now in left nostril. 4th – 9th. – No medicine and no symptoms.
13c. Jan. 10th. – M., afternoon, and evening, 20 gr. of 1st trit. Pain as of dislocation in right wrist – joint and in last phalanx of index, with weakness and feeling as if asleep on both hands, especially when he laid them on a hard object or put them in his pocket; throughout whole day fine shoots, which rapidly disappeared, in different parts of general integument, with itching obliging him to scratch, especially on toes, right index, lips, glans penis, and prepuce, and in axilla; much appetite. 11th. – 5 a. m., wide awake and completely refreshed. Took 3 doses each of 20 gr. of 2nd trit. fine shoots in various parts of body, especially lips and through whole length of urethra; feeling as if asleep in left hand and arm; painful weakness in arms; tension above knee, with feeling as of lower limbs were too short, in going upstairs; constipation; sour taste of salvia; frequent accumulation of water in mouth. 11 p. m., much thirst. 12th. – Fine shoots in various parts of the body, quickly passing off. 9 p. m., took of the raw material. Directly after, inclination to vomit; yawning, with lively humour, is disposed to make nonsense; in sitting, great uneasiness in lower limbs; burning shooting on back of toes; in standing, feeling as if net were before eyes, not lasting long, recurring three times; feeling as if left eye were smaller than right; fine shoots in skin, especially of lips, in axillae, on breast; scraping feeling in pharynx; pressive pain in right half of head towards vertex, of short continuance; much thirst, particular desire for wine; voluntary movements with right hand; shooting in rectum, feeling as if raw in same part., so that he cannot sit; redness round about anus. 13th. – in m. on going out much secretion of mucus from posterior nares obliging him to hawk constantly; much hawking of watery mucus; emission of much offensive flatus. After dinner, urging to stool; hard friable stool; burning in rectum in walking throughout day 14th. – M., in bed, feeling of weakness, as if paralysed, in both hands and right foot, disappearing after rising; emission of much offensive flatus in forenoon; frequent micturition whole day; urging to stool as if looseness would come on, all day; after dinner, consistent stool. Very much appetite; ate almost twice as much as usual. 10 p. m., great uneasiness with shoots in feet, so that he cannot remain seated and is obliged to keep moving the feet backwards and forwards. In going about this is relieved. Much thirst, particularly for wine. He has become during the last few day remarkably stout and looks very well. Great desire for coition. 15th. – Emission of much flatus; frequent micturition, particularly after dinner. Bread tastes the best; he can scarcely eat enough of it. Much thirst for wine. All wines appear sour to him, although others do not confirm this. 16th. – In m. in bed feeling of weakness of right inferior extremely as if it were lame; relieved by standing up. 17th. – Boil on lobe of left ear, which pains very much, burst in 6 day and discharged pus and blood. In consequence of taking cold was seized with influenza, which confined him to bed. From this period all the salt symptoms ceased. For the subsequent 8 day he had still constant soft evacuations. From time to time there showed themselves, even after four weeks, any of the previous phenomena, particularly weakness of right hand in holding an object, and uneasiness in legs about 10 to 11 p. m. (Ibid.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.