6. DETWILLER, from 30th dil. Giddy pressive headache; headache in forenoon; violent itching on scalp and over whole body. Violent pain in right eye in a person who had been blind more than ten years, though without pain; fog before eyes, in evening a bluish – grey ring, about 6 inches in diameter, around the light; a beautiful bright blue ring about the light, filled with fiery rays (2nd d.), fiery ring with fiery rays (3rd and 4th d.). Swelling of face with much heat and redness; burning pains in face; swelling of cheeks and redness of whole face, repeated after 2nd dose. Gums bluish red, swollen, and very painful; swelling of gum of upper front teeth, with throbbing pain in it, evening, next day it was worse, with burning and throbbing; violent painful swelling of gum of anterior lower incisors, 3rd day, disappearing on 5th day; gum is painful, with toothache; aphthous and denuded spots on mucous membrane of buccal cavity, preceded by burning pain and rawness (3rd day, relieved 6th d.); burning and throbbing pain in mouth (2nd day after 2nd dose); violent burning in mouth and swelling of lips and gum of lips and gum (3rd d.); violent burning pains in mouth and face; rawness in mouth and throat; disgusting bad taste in mouth (3rd d.). Burning in throat; rawness in throat, without hawking of mucus; difficult swallowing of food and drink, as form hindrance in region of cardiac orifice, small quantities only can get into stomach after long intervals. Violent pain in region of spleen while driving; obliging him to stretch out straight, which afforded a little relief, lasting 2 day, but only while so traveling; stitches in left side extending into chest, so that breathing was very difficult; distension and tearing in abdomen for 4 hours, with chilliness; intolerable pains in abdomen with burning and distension. Disagreeable, dry, scraping feeling at epiglottis and vicinity (Ist to 4th d.); hoarseness with burning in throat; respiration difficult on account of stitches in chest. Stitches in nape of neck and in whole back for 3 day; sticking in right arm, with feeling as if it were asleep, with violent itching in both arms, hips, and lower limbs. disappearing gradually in 10 day after 2nd dose. Feeling as though arms had fallen asleep, with sticking in them; violent tearing in left shoulder, extending through arm to tips of fingers in m. (immediately after 2nd dose, and again on 3rd d.); tearing in joints of right hand (4th d.). Swelling of left leg and foot. Boils 1/2 inch in diameter near spine, with violent burning – throbbing pain, disappearing without suppuration; itching near left eye; violent itching on left arm; violent itching on hips and lower limbs. Very violent general chill, with tearing and distension of abdomen; a febrile chill with thirst and pain in forehead, in evening (Ibid.)
7. GROSS, from 30th dil. A kind of loss of ideas. Headache with vomiting of food; violent headache, with flickering before eyes, as if nasal catarrh would break out; pressive headache for 2 day, on 3rd day congestion to head, with flickering before eyes in wonderful angular jagged figures, followed by headache and difficult hearing; tearing in head; boring and sticking on vertex. Eyes became weak, at a distance he still sees well, but near very indistinctly, especially in evening, -on reading flickering before eyes, and letters became indistinct. Cracking in front of ears. Catarrh and cough with easily loosened expectoration, with moderate heat of head and hands, dim eyes, violent palpitation of heart, together with rash over whole body, having appearance of small spots without being elevated, as large as point of a pin, sleep at n. restless, with moderate perspiration; frequent attacks of catarrh, which, however, did not fully develop; blowing of blood from nose, with troubles in trachea. Very bad colour of face, and general discomfort; pain in face, tearing above orbit, with vomiting of food. [In a girl at puberty who was pale, with loss of appetite.] Toothache extending through jaw to ear; raging, jerking, tearing, dull sticking in roots of lower teeth, often extending through upper jaw to ear, periodic, always after waking form sleep, soon after eating, also from warm and cold drinks. Crawling in throat at n., causing a short, incessant, hacking cough, during day sore-throat was still worse. Pain in throat on taking hold of it, extending even to nape of neck, with sticking all;ways on swallowing, and scraping on swallowing bread, as if everything were raw, together with dryness of throat, without actual dryness of tongue. She loses all appetite, especially for bread and rolls, the usual milk causes nausea, yet everything has a natural taste; no appetite for breakfast; smoking always causes nausea, for 16 day (in one accustomed to it); nausea and pain in stomach. Vomiting; vomiting of food; forcible vomiting of all food, with pain in head and abdomen; vomiting of blood; much pain in pit of stomach, constant nausea, with qualmishness and diarrhoea; she was attacked with the most frightful cramps and pains in stomach every evening at 5 o’clock, with violent eructations, retching, and vomiting, though only some mucus was raised, also at other times nausea, with coated tongue and pain in stomach; pressure in stomach, more or less severe, extending from pit of stomach into chest, as if one would be taken with colic, or as if from incarceration of flatus. Abdomen distended as if internal parts were greatly dilated; abdomen frequently much distended, with disagreeable sensation as if inner parts of ligaments from stomach were very much stretched, -on this account she was obliged to wear the clothes, especially about the stomach, very loose, otherwise it was very distressing, and even in bed she was obliged to loosen and pull up the night-dress to avoid pressure, she dared not lay arm across abdomen on account of pressure; a certain tension and flatulence in abdomen on account of pressure; a certain tension and flatulence in abdomen prevents her from walking far; violent cramps in abdomen during menstruation, it seems as though a knife were thrust through abdomen; colic with vomiting of all food; attacks of colic after confinement with return of other previous symptoms; pain in intestines caused by shock of cough. Discharge of blood from anus. natural evacuation, followed again by diarrhoea; diarrhoea-like stools 5 or 6 times daily. A few day before and after menses urine at first clear, after standing awhile deposited thick sediment like a beaten egg, -there-with peculiar sensation in bladder, not exactly painful, but very disagreeable, and associated with a certain desire to urinate. Emissions 3 evening in succession, which never happened before, followed by decided weakness and even headache; emission several times at n. and profuse sweat; means recurred after 3 weeks (they usually returned every 28 d.) Feeling as though a plug were fixed in larynx, which moved up and down, with a short cough, is unable to lie down, blows bloody and purulent matter from nose; if lungs are irritated in any manner, as, for example, by tobacco smoke, a violent irritation frequently causes uninterrupted cough for m., so that chest is most violently racked, and all the blood derived to the head and face; spitting of blood; unable to get breath, must sit up, then rattling of mucus with alternations of coldness and heat in pit of stomach, and general chilliness and flushes of heat, risings into oesophagus with efforts to vomit, whereby only mucus is raised, which collects in the mouth in large quantities (after 48 hours); the chest feels swollen, with violent pains in it, dares not touch it at night; pains in left side beneath breast, &c. A former paralytic and sprain-like pain in small of back became far more acute; dull stitches (jerks) in small of back on every motion, so painful that they distorted the features. Limbs stiffly outstretched, head bent back, eyes distorted, for 1/2 m. A kind of paralysis of left shoulder in m. on rising, as from lying in an uncomfortable position, it however continues and afterwards recurs, but especially in m. when dressing and on bending arm backward; tearing in left hand, extending into upper arm. A former tearing in left hip returns; posterior portion of thigh, especially towards knee, becomes painful as if swollen, knee is swollen with intolerable pain, especially in hollow, chiefly on touch; knee is thick, painful on standing, he can scarcely walk, and only after walking while it is endurable; tension in knee, stretching it out was very difficult; frequent violent tearing in feet, especially in evening, with heat in them. Constant and fatiguing labour does not grow with him, he soon becomes weary; weakness, especially of arms, -of legs; great weakness now and then during day; great weakness in m. after rising, she constantly desired to sink down again, on the slightest exertion the arms sank down exhausted, therewith she felt her heart beat, often also in evening she was very weak, so that she could not remain up long; he would constantly sink down from weakness. Constantly very sick for 10 day before the menses, constant beating in temples, headache, and cutting in abdomen, so that she feared the occurrence of the menses every moment; after confinement all her former troubles (pain in left side beneath breast, tearing in right foot, violent headache, and attacks of colic) became again more violent, though only transient. Papular eruption on right forenoon, afterwards over whole body; pustules, especially on thighs, as large as head of a pin, surrounded by a red areola, some of them as large as cornea; a red spot as large as hand appears on left shoulder and exudes moisture, small vesicles suppurate and break; itching between fingers and on knees. Great sleepiness after supper, he can scarcely keep awake, and in m. he awakes late; sleeps over the usual time next m.; he is unable to sleep on account of internal restlessness; abdomen and chest seem swollen, violent pains in chest so that he dares not have anything rest on the chest; sleep at n. restless, with moderate sweat, catarrh, cough, rash; sleep very restless, on rising in m. weakness over whole body, especially in arms and feet, after bad sleep she rises less exhausted than after good one; he awoke at n. about I or 2 o’clock, sleep was so light that he heard everything, and from then till m. he was unable to sleep again, therewith he easily became peevish and mistrustful, with no appetite for bread. Soon after dose feeling of coldness in stomach, as if an intermittent fever which he had formerly had would suddenly return; violent fever every evening, with loss of appetite and headache, internal chill with external heat, in evening great febrile heat which lasted all night; moderate heat in head and hands, with nasal catarrh; frequently very hot hands and feet with frequent violent tearing in latter, especially in evening, she does not know where she shall put her feet in order to find a cool spot; slight transient orgasm in chest; perspiration at n. with catarrh and cough; profuse sweat at times at n. (Ibid.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.