6 b. Prover now, from November 3rd, took globules of 3x (it not said how frequently). On 1st day left leg numb in evening 2nd day., rose with fulness of head; pain in bridge of nose and aching in articulation of jaw; left leg numb; temper touchy, irritable 3rd day, slept badly, dreams of distress; unrefreshed on waking, utter towards noon; head clear, but face hot and smarting for 2 hours 4th day, sleep comfortable but dreams distressful; after tea pinching pain in bowels, which became much relaxed 5th day, fulness and pain with heat in vertex on walking; same dreams; pain in head worse after dinner. For rest of proving had at various times fugitive pains in face, shoulders, limbs, and fingers, of “laming” character; also crampy pains in abdomen and numbness of legs. Catamenia appeared November 19th (3 days too soon); increased in quantity, but attended with sickening pains in belly which she never had before (Ibid., p. 325.).
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.