5 c. July 12th, resumed experiment, taking increasing doses (12-25 dr.) 3 times a day up to 15th. ON 16th urine and salvia increased. At times heat in head; pulse 80, full and strong. In these and other respects as in former proving. Up to 20th continued 25 dr. 3 times a day. 20th. – Pulse 60, but action of heart remarkably strong. From 21st – 23rd 30 dr. doses were taken, and from 24th – 26th 40 dr. On 26th, pulse strong and full 46 beats only, their impulses rapid, separated by a considerable interval. Action of heart vary energetic, but strength somewhat diminished.
5 d. July 26th, took 200 dr. at 2 p. m. 3 p. m., nausea, uneasiness of stomach, followed by vomiting of mucus, vertigo, headache, mental faculties disordered, heat of skin, pulse 65, hard and full; heart’s beats strong and jerky. 8 p. m., pulse 28th, soft and irregular; prostration and weakness; heart’s bets very irregular and hurried, but sometimes 10 – 12 beats in succession of moderate strength. Disposition dejected; intellectual faculties affected. – 27th. Took 50 dr. every 8 hours. – 28th. In same state as on 26th. (W. HUTCHINSON, Four. dies prog. d. sc. et. in state. med., 1827, vi, 218).
6. Dr. SCHRON, September 2nd, early in morning took 1 gr. of powdered day in water. An hour after felt pressure in stomach, and p. m. pain in right frontal region. 3rd. – Early he took, fasting, 2 gr., and soon experienced great nausea, confusion in head, and frontal headache as on 2nd; slight pain, apparently in cardiac region, and 1/2 hours after pulse is softer, smaller, yet quicker. Nausea continued several hours, then came dryness of gums and pharynx. On getting up after sitting giddiness and marked weakness of legs. pulsation of heart sore and weaker than usual. Two hours after giddiness passed away had pressure at stomach and copious salivation. At noon saw bright sparks before right eye. In afternoon unusual perversion of vision, with anxiety and sense as if finger pressed on eyeball. In evening took 3 gr. Same symptoms occurred, but there was now much greater dryness of mouth and pharynx, with thirst so great that he had frequently to drink during night. Pressive pain in eyeballs with dilatation of pupils, especially right 4th – 7th. – He took daily 1/2 gr. morning, noon, and evening. Scarcely any of the former symptoms were experienced, but he had considerable disturbance of the circulatory organs, so much so that on night of the 3rd and 4th days he had, on account of palpitation and anxiety, to get out of bed, to walk about, and open window. Pulse was 100 and strong. Head congested, with rushing and tinkling sounds in ears. Lasted several day Palpitation less severe on the night of 5th, but frightening him out of sleep. No action was experienced on urinary or genital organs. (WIBMER, op. cit.)
7. Dr. JORG. aet. 45, middle sized, constitution robust, temperament sanguineous choleric, took August 19th, 8 a. m., 1/4 gr. of powdered D. with sugar and water AN hour after he felt his head affected, also pressure cover occipital region, which continued at intervals till noon; at same time he observed that he saw objects in a falls flight. From 10 -11 he felt increased motion in digestive canal; this passed into slight griping pains in bowels, extending from hypogastrium to testicles. At 11 a. m. the pain disappeared, but desire to urinate, with itching excitement of glans penis, continued until afternoon. 20th. – Took at 8 a. m. 1/2 gr.; soon experienced scraping in throat with hoarseness; former soon disappeared, the latter continued all day. At 9 felt headache as on 19th, but more severe; it disappeared at 12, but recurred several times p. m. From 10 – 11 borborygmi and griping pains which lasted an hour; urine passed in greater quantities than natural, without pain, but with peculiar irritation of glans penis as on 19th. This continued until noon of 21st; appetite and pulse not affected. 22nd, 8 a. m., took 3/4 gr. of D. and 3 gr. of magnesia in 3ss of water. Experienced rawness in oesophagus and windpipe, griping pains and desire to go to stool. At 10 a. m. had a motion which contained faecal matter. From 9 a. m. affection of head commenced, which J – compares to a spiritual intoxication, describing it as an apparent expansion of the nervous life beyond the usual limits. This state of mind passed away without leaving any headache. In afternoon flatulence, heartburn, and sensation as if throat were compressed by enlarged tonsil. Until morning of 23rd there was much and even painful excitement of genital organs; after this excitement ceased urine flowed abundantly. 23rd. – Took 1 gr. in 3ss of water; experienced much the same symptoms as on 22nd, relation and weakness, bodily and mental. At 11 a. m. headache at vertex lasting an our; 11 – 3 sharp burning and scratching in oesophagus. Appetite was unaffected throughout proving. ON 22nd and 23rd pulse was smaller and weaker, never slower, but occasionally quicker than usual. (Materialen, 1825, sub voce.)
8. Frau Ch -, aet. 45, short, slender frame, but healthy and of sanguineous temperament. On August 18th, 8 a. m., took 1/4 with 4 gr. of sugar. Shortly after felt pain in hypogastrium, lasting 1/2 hours followed by more or less heat in stomach, extending to oesophagus. This continued till evening 20th, 8 a. m., took 1/2 gr. with 7 gr. of sugar in 3ss of water, and shortly after experienced scraping in oesophagus. After 3/4 hour felt slight cutting pains in stomach, and from 9 o’clock slight affection of head with pressive headache. At 10 desire to make water, which was not relieved by micturition. In afternoon suffered from pressive pain over crown and back part of head; also from sharp burning pain extending from stomach to throat; secretion of urine increased until bedtime. 21st. – After a restless night, had headache, as on 20th, bust less severe; desire to micturate cease at 3 p. m., and increased secretion of urine was much diminished by evening. Burning in stomach lasted until evening 22nd, 8 p. m. repeated dose, as on 20th, with addition of 1 1/2 gr. of magnesia. She soon experienced slight headache, griping in abdomen, followed by increased warmth of whole body; desire to urinate. From 10 to 11, pain in region of kidneys; the urine increased to such a degree that she passed every 2 hours more than she usually did in 24; no increase of thirst. Headache disappeared on 23rd; increased secretion of urine continued until evening of 24th, and was very troublesome, especially at night. Besides these symptoms she felt weak and exhausted. From 22nd to 24th vision was weak and dim; pulse kept small, weak, and a little quicker than usual. (Ibid.)
9. OTTO, aet.22, tall, slender, and of lymphatic constitutions, took, August. 11th, 1/2 gr., which caused giddiness, lasting 1/4 hours. On 12th, took 3/4 gr., with 2 gr. of magnesia, in 3ss of water; scraping and heat in pharynx, and longer – lasting giddiness. On 13th, took gr. 1 1/4 with 5 gr. of magnesia i 3ss of water. Same sensations; p. m., copious urination. On 16th, gr. 1 1/2 at 8 a. m. At 9, pressure on head for 1/2 hours, diminishing power of thinking. After dinner (eaten with great appetite) giddiness with sudden dazzling of eyes, followed by sparks as if around eyes, or 1/4 hour. From 3 – 10 p. m. passed urine copiously 6 times; after standing it deposited thin brownish sediment. Genital organs excited; pulse smaller and weaker. ON 15th, at 11 a. m., he took 2 gr., feeling soon scratching in pharynx. Towards noon he experienced confusion in head; this became more and more a pressive pain, which from vertex extended over whole head. As it passed away, he felt peculiar sanction in eyes he had experienced after previous doses, sight suddenly confused as when one passes from darkness into a bright light, then as if sparks were floating in air; these symptoms and attending giddiness did not last above 1/4 hour. There was slight increase of urine, and for 1/2 hours great excitement of genital organs; pulse small and slow. Prover slept well, but woke on morning of 16th with same headache, increasing during whole day. Had not before or since suffered from a similar headache. Pulse was weak, soft, varying frequently in tension; urine became much diminished. On night of 17th again slept well, and headache of previous day was nearly gone. 17th, 8 a. m., took 2 gr. in 3ss of water; soon after felt scratchings in pharynx, lasting 1/4 hours; an hour later confused feeling in head, affecting thought, and passing into formerly reported pressive headache Diminution of pulse and excitement of kidneys and genitals as on 15th. Appetite slightly diminished. Slept well on night of 17th and 18th, but woke with same headache as before. This headache continued throughout day so severe that prover was unable for any work, and obliged to go early to bed. Pulse was very weak, with varying tension (Ibid.)
10. SIEBENHAAR, aet.22, middle sized, constitution robust, temperament melancholic, on August, 9th, 8 a. m., took 1/2 gr. of powdered D. mixed with 3 gr. of magnesia in 1/2 oz. of water, and on 10th at same hour 3/4 gr. in same mixture. He experienced burning and scraping in pharynx, followed at 8:30 by giddiness, sparkling before eyes, double vision, and acceleration of pulse. These symptoms entirely disappeared in 1/2 hours. 11th. – Took 1 gr. with 3 gr. of magnesia. Scraping in throat was a constant symptom; sparks before eyes and giddiness appeared about 8:30, and disappeared in 1/2 hour. Pulse was a little quicker than usual, but after effects of medicine had passed away it became slower and smaller. Genital organs were much excited; no increase of urine. 13th, 8 a. m., took 1.1/2 gr. with magnesia as before. He immediately experienced scraping in oesophagus, dizziness, and sparks before eyes, which did not last long; but irritation of the genital organs was so very troublesome, as to induce him to suspend med. for a few days 17th, 8 a. m., took 1 1/2 gr., but without magnesia; it tasted more bitter than before, and produced scraping and burning in pharynx; pulse and digestive organs not affected; urine normal, genital organs much excited. 18th, 8 a. m., took 2 gr. in 1/2 oz. of water. Same symptoms were experienced as on 17th; towards afternoon secretion of urine was increased. 19th. – Took 2 12/ gr. Same symptoms appeared as on 18th, an disappeared by afternoon. 20th, 8 a. m., took 3 gr.; symptoms as on 18th. By 10 a. m. secretion of urine was increased and forced him to pass water every 2 hours, and twice during night. Genital organs were much affected; the pulse remained undisturbed. (Ibid.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.
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