13 b. On April 14th, at 7 a. m., I took at one dose all that remained of my tinct., about 78 dr. In 1 hour flying stitches in brain, mostly under coronal suture; perceptible pulsations in head; pulse abnormally frequent; rumbling in abdomen; in 1 1/2 hour stitches in left thumb; heat and dryness in mouth; frequent yawning; in 5 hours flying stitches in right shoulder; stitching pain below left jaw, recurring; tensive feeling across over hypochondria. After dinner a somewhat soft stool, with wind; in 7 hours flying stitches in left ear, lasting a few morning; p. m., rapid and sensible pulsation in carotids, also in head; some tightness across chest, with desire for deep breathing; dryness in mouth with thirst; after 11 hours heat in sacrum extending to rectum; flying stitches under left clavicle. (Ibid.)
14. Dr. RUCKERT, aet. 51, in good health save for remains of (second attack of) whooping-cough from previous summer. On December 1st, 1852, in morning, fasting, took 8 dr. of 1 dil. in water, and at night a similar dose. 2nd. – In morning feeling of pulsation in belly and chest, as of strong determination of blood from former to latter. Several times during day, but especially in evening after eating, feeling of ebullition in chest, and of working there as if something were alive in it. P. m., cold fee, shivering. 3rd. – This morning boiling feeling in chest returns. 4th. – Chest easy; after food pressive pain in head, dissipated by a nap. (Ibid.)
15. a. E. R -, a girl of 20, brunette, health good save for some chronic conjunctival irritation. On November 11th, 1853, took 4 dr. of 1x dil in water in morning. No change. 27th. – Same dose. AT 11 a. m., pain in right teeth, and at 3 p. m. same in left ear, both transitory. 28th. – In morning, 8 dr. Towards noon great heat of face, and soon after eating headache over left eye, better in open air, but persistently troublesome in room; towards evening very violent pressure move eye, with desire to shut it and to press on forehead; it lasts throughout evening and increases at bedtime, with nausea. 29th. – In morning in bed violent colic immediately on waking, with digging in bowels, thereupon a single diarrhoeic stool. 30th. – In morning, 8 dr. Well through day; in evening violent stitches in ears, and after (cold) supper intense heat in right cheek and eye with cold feet. In evening same dose. Sleep good. December 1st. – On awaking some abdominal pain and great heat of face. Took 8 dr. digging in abdomen and some diarrhoea; p. m., great heat of face, but with warm feet. In evening 8 dr. 2nd. – In morning, same dose. On 29th lips had cracked, unusual in such weather as then existed; on 1st they were much fissured, and to-day can hardly be moved; lower lip, from which hardened skin had peeled off, very painful. 3rd. – In morning same abdominal pain and (4 times) diarrhoea. Colic lasted all day. On forenoon and evening pain behind left ear, as if glands were swollen. 4th. – Colic and diarrhoea as before; lips still painful and readily cracking. 5th. – Colic and diarrhoea only immediately after rising; so also on 6th, 7th, and 8th; pain only gradually disappearing after this.
15 b. On November, 3rd and 4th, 1853, took 2-3 dr. of 12th dil. without effect. On 6th, 8 dr. On going to bed considerable palpitation, such as she has never experienced before. (Ibid.) 16. Dr. TEICHMANN, aet. 36, in good health, save for some haemorrhoidal troubles. February 28th, 1857, at 7:30 a. m. 3 dr.of 15th dil.in water. March 2nd.-7 dr.at 7.30 a.m. 3rd- Towards noon feeling of pressure in left upper arm near elbow, which in course of afternoon became severe on moving shoulder, and especially on raising arm, so that he could not get on his coat. When quiet he felt nothing, and night was painless and restful. During 4th and 5th this pain gradually subsided. On 7th, 5 dr. of 3rd, and on 8th, 5 dr. of tinct. without result. On 15th, at 7 a. m., 7 drops of tinct. On 16th, awoke at 5:30 a. m. with pressure and discomfort over transverse colon; fell asleep again in 1/2 hour; on rising feeling had not quite gone, but was slighter. (Ibid.)
17. Dr. BOHLER found, both in himself and in several members of his family, though all little sensitive to medicine, that after almost every dose (3 dr.) of 15th dil, as also afterwards of 3rd, there occurred one of two loose, almost diarrhoeic stools, to which they were not at all subject. (The doses were taken in evening, 1 hour before bedtime.) After 3 dr. of 3 rd in evening there came in 1/2 hour scraping dryness in throat, and tickling cough; also slight drawings in upper jaw and orbital margin, soon passing off and alternating with irritation in throat. After 6 dr. immediately tingling sensation in tongue and throat. (Ibid.)
18. Dr. SYBEL took repeated doses of 15th, of 1x, and of tinct. up to 20 dr. 3 times a day, but without effect. (Ibid.)
18. a. I held for 2 morning on the tip of my tongue a slice of the fresh juicy root, slightly bruised. Tongue became heavy, later stiff, last numbed, so that for 6 hours it was almost entirely insensible. Without any remedial means tongue then regained first its mobility and then its sensibility.
18 b. Three gr. of same were infused for 1 hour in S-‘s accustomed wine (4 oz.), and the whole (Filtered) drunk by mouthfuls. It seemed sightly harsh and astringent, and produced tickling in larynx, and a little short dry cough, without any gastric disturbance. But a few morning later I felt burning in the urinary passages, followed soon by abundant flow of pale urine.
18 c. Two hours after mid-day meal I swallowed nearly 1 gr. of same in bread crumb. After 1/4 hour there ensued burning in stomach at a fixed point, flying pains in head, and chill coursing along spine. Burning lasted 1 hour, and spread all up sternum, then into abdomen, shifting from place to place, getting more acute, and assuming character of colic. After 2 hours more I felt in lumbar region and along urinary passage a considerable irritation, accompanied with continual desire to micturate; there passed, however, only a very small quantity of burning urine, with strangury. Soon after followed very painful rectal tenesmus, with a small stool, after which came a quantity of transparent, yellowish, kinky mucus, with some slight tormina. Urinary irritation persisted; there was also great epigastric tension, violent pains in head, some attempts at hiccup. Pulse was very excited, appetite nil, thirst lively. A drink containing lemon- juice was now taken frequently; some stools followed, and after a few hour great relief to all save urinary symptoms, which last continued even through night. Next morning I felt weak, free from gastro-enteric pain, but micturition continued difficult and excited frequent and painful urgings to defecate. Head was heavy, but without pain; slight burning remained behind sternum. A demulcent drink was now taken, after which urine flowed freely, changing from fiery-red to brown, then green, lastly pale. Appetite did not return this day. On 3rd day only some debility and short lancinating pains in joints. Next day quite well. (STORCK, Lib. de Stramonio, etc., 1762.)
19. a. March 19th, 15 dr. tinct. 6 times a day. Transient headache in evening. – 20th 15 dr. 7 times a day. All day weak and weary, all right in evening.
19 b. After taking for several day from 15 to 30 dr. several times a day., took on April 2nd, at 7 a. m., 45 dr. all at once. No relish for breakfast; some rumbling in bowels and urging to stool, which was watery, slimy, of blackish-brown serpentine colour and feculent, smelling like fresh bile or blood after standing for a few morning in the water-bath. After 1 hour, and at 1 p. m., stools of same character, after the last quite exhausted, lazy, sleepy, limbs prostrated, no inclination or work. Sense of smell very much exalted, strong – smelling things extremely repugnant. Tongue rather furred, appetite diminished, thirst increased. After dinner slight nausea, was very cross, and slept very restlessly for near 20 morning, but unrefreshed by the siesta. Chilliness all day till 7 p. m. At 7:30 p. m., ate pretty much as usual. After supper much more lively. Urging to stool still but slighter, and some rumbling in bowels. Another stool at 11 p. m., and next day 2 loose stools. (BOCKER, Beitr., ii, 204)
20. The following additional symptoms were observed whilst and after taking tinct. May 3rd, 11:50 a. m., gnawing in belly that soon went off. After supper walked slowly for 1/2 hour and perspired considerably. Lay awake for 2 1/2 hour in bed. All night slight perspiration. – 4th. No symptoms except a loose stool in evening – 5th. Slept well, perspired moderately. When visiting patients perspired, was rather tired, and on coming home perspired profusely. After dinner at 1 p. m. felt cold; 2:45 p. m., a copious loose yellow stool, thereafter some pain with rumbling and feeling of movement in abdomen; this went off, but recurred later with urging to stool without pain. Appetite good. – 6th, 10 a. m., painless movement in bowels for some seconds; then it went off and returned every 1/2 hours. Perspiration in morning not in afternoon. 4 p. m., rumbling and discharge of flatus. After supper full feeling in abdomen, relieved by a copious pappy stool at 10 p. m. Afterwards movements in bowels. Perspired at night – 7th, 8:30, thin stool. 4 p. m., rumbling in bowels, and thin yellow stool ejected with violence; during and after it a transient uncomfortable almost painful feeling in abdomen. Both a. m. and p. m. moderate perspiration. While walking, 5 p. m., perspired considerably. 11 p. m., a copious loose stool. – 8th, m., rather tired; this went off after getting up. Slight pain in abdomen. After siesta more tired and lazy than usual. 4:30 p. m., urging to stool, slight discomfort in bowels. 5 p. m., thin loose stool. – 9th, 10 morning before taking med., feeling of movement in abdomen followed by stool, at first normally consistent, later loose. 2 p. m., movement in bowels recurred and lasted till evening; at 11 a loose stool. – 10th. Soon after taking med. slight rumbling and movement in bowels lasting all morning (Ibid., p. 220.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.