7. W. S. -, woman of 24, single, in good health save for rather frequent headache and costiveness. after 2 doses of 20 gl. of 15 dil. nothing but increased appetite. after 2 dr. of same in water very restless night, with night mare, and next morning weakness of limbs. February 2nd, at 9 a. m., 20 gl. of 3rd dil.; immediately, chilliness in room, giddiness and palpitation all day. Last symptoms recurred after 40 gl. on 5th. After 2 dr. on 7th deep sleep, weakness in limbs. After same on 10th, at 9 p. m., burning heat and giddiness. ON 17th, at 9 a. m. same; pulse before taking it 70, 2 hours later 60, in evening 65. March 6th. – Four drops; palpitation. ON 10th, took 2 dr. of tinct.; pulse before taking it 70, 2 hours later 65 and very weak, in evening 57, an hour later 70. On 14th, 4 dr.; chilliness in thorax; eructations with water. On 17th, 4 dr. in evening; pulse after taking it 50, after an hour 60, next morning 60, towards noon 75; heat in forehead; giddiness. (Ibid.)
8. C. Such-, woman of 30 and single, strong save nervous system. Doses of 15th dil. taken while a catarrh was passing off, seemed each time to renew it; she had also after one dose itching over whole body, and a slight eruption. From 3rd dil. latter, she had pain in stomach, giddiness, and sense of great weakness on getting up in morning. With next catamenia (unwonted), heaviness and aching in feet. From tinct. some palpitation and giddiness with, on one occasion singing in ears and debility, also great appetite. (Ibid.)
9. Dr. GSCHLADT, aet. 35, thin and weakly, venous constitution, bilious temperament, great irritability, pale face, dark complexion. December 30th, 1853, took 20 gl. of 15 dil., at 4 p. m. Soon after frequent flatulent eructation; repeated yawning; dizziness after walking, so as to cause fall from chair. In evening, unusual drowsiness. Deep sleep till midnight; then woke with heavy pressure on stomach, and lay awake for 2 hours, with audible palpitation, dry heat of surface, dry mouth, slight darting pains in wrists and elbows, dragging pain in sacrum. Woke tired in morning; boring pain over eyes; sacral pain better on moving; face paler; eyes dim; copious stool. Appetite great. P. M., persistent chilliness and unusual drowsiness. Irritability greatly increased all day Good night, and next morning quite well. On January 4th, at 4 p. m., took 100 gl. of same, with similar results, including also palpitation on 1st day, and nausea to vomiting on 2nd. Sacral pain extended to hip. On 10th, 25 gl. of 3rd dil., with similar results, heart being also oppressed. On 14th, 50 gl. produced same effects, with giddiness. (He woke each night after dose at midnight, and lay awake 2 hours as at first.) Same also from 2 dr. of 3rd on 19th, and 4 dr. on 24th. About this time he became aware of existence of two dry wart – like growths on neck, which had arisen during proving, and after 6 weeks disappeared by scaling off. On Feb. 4th, took 2 dr. of tinct. at 10 a. m. Same general effects, but colicky pains, weakness of limbs, and general weariness and restlessness were added, and there was more decided pain in joints (shoulders and knees). On 12th, 4 dr. Same symptoms; joint pains relieved by motion (as before). On 13th and 14th urine copious, golden yellow; clear at first, but afterwards showing a suspended white cloud. March 15th. – Six dr. at 9 a. m. Same symptoms, but more marked; in afternoon drowsiness, shivering, pallor, anxiety about heart, hunger, variable pulse. Next day with other symptoms, tongue white; and on 17th, urine slightly scalding. On 31st took 6 dr. at 9 a. m., 8 at 3 p. m., 10 at 8 p. m. with renewal of all old symptoms, also ringing in right ear and deep hollow voice. The action of the several doses taken throughout seemed to extend from 24 – 72 hours. (Ibid.)
10. a. Dr. BRUNO LINCK, bilious temperament, strong and healthy, but with tendency to catarrh and colic. January 19th, 1853. – Shortly before going to bed, took 4 dr. of tinct. After lying a while in bed blood began as if were to boil, sweat on chest and head, peculiar feeling at heart with some irregularity of beat, and pricking and itching in several parts. Sleep afterwards sound. Repeated dose next evening, with similar results; itching was burning, and scratching sent it elsewhere; also some cutting in abdomen. After same dose next evening on blowing nose same cutting pain, but in lower anterior thorax; nothing else noted. ON February 5th took 5 dr. gradually during morning, and p. m. 4 dr. at once. In 1/2 hours after last same cutting pain on left side, uninfluenced by breathing; dulness in head. In evening remittent dragging pains in thigh-bone, and headache about left temple, relieved and finally disappearing in bed. Sleep good. 6th. – Quite well on waking; but after rising headache gradually returned, and by evening was severe, pain heavy and dull, in upper and back part of head; with it great tension of jaws; relief after supper and gradual decline in bed. On waking after a good night pain only on small spot of right forehead, pretty severe for 10 morning, but remaining in less degree all day; also pain in left thorax as before. On 8th and 9th feeling all days as if headache would return; on latter thoracic pain, shifting from right to left and appearing lower, at last settling into persistent pain over spleen; in evening colic and threatened diarrhoea. On 10th splenic pain had disappeared he had pinching and cutting here and there on chest, and, for a short time, in left arm; also wandering pains of burning itching character, after scratching skin becomes red, and pains shift. On 11th and 12th free from all complaint, but at night could not lie comfortably on left side from splenic tenderness.
10 b. After repeated experiments with a tinct. from an old school pharmacy, very feeble indications of action were manifested, although he took 15 and even 20 dr. at once. The only marked and recurring symptoms were oppression in head, tearing pain from right patella backwards; cutting-tearing pain in hepatic region; burning itching in various places almost simultaneously; dragging in left hypochondrium.
10 c. Again proved homoeopathic tinct. (equal parts of juice and spirit). On march 13th took 10 dr. with water. Slight pain in left testis, very sensitive, as if squeezed, on putting down left foot in walking, evidently from jar (nothing felt on pressure); nausea; cutting-tearing pains on chest. In evening pain in testis again for some time tearing pains on outer side of left forearm, as if in fascia, sudden shooting-tearing pains in lumbar region on both sides. 13th – Oppression in upper and back parts of head; tearing pains about left foot; severe pain in leg, as if from cold, especially on tibia, with coldness of leg and of whole body, even in bed; a. m., pain in testis as before. – 14th. Same feeling in leg; cutting and tearing pains in chest. 15th. – Pinchings on tibiae, with coldness in bones (as yesterday) while writing such violent pains over right thorax that he was compelled to desist, unaffected by movement or deep breathing, then suddenly such a severe crampy pain there that he started up in affright. 16th. – Tearing under patella; pain at end of one finger on palmar surface as from a splinter, recurring at intervals. 17th. – Took 10 dr. of officinal tinct. seminum. Slight occasional pain in extensor surface of left forearm, extending to some fingers; pinching tearing pain in right tendo Achillis; lachrymation in open air, so as almost to impair vision (noticed slightly for several day); smell as of smoked ham under nose; pressive pain on left eyeball; eyeball very sensitive pain in front of shins; dull pain as from cold, or like “growing pains” in bones; very sensitive drawing in left forearm on extensor side, as if some nerves were being stretched, at intervals; remarkable chilliness of skin on hands and feet even in bed; coldness of whole body even in a room; small round pimple on m. m. of lip. 18th. – In evening 10 dr. Long stitches in left elbow, spot remaining tender for some time; tearings, very fine but penetrating, on extensor surface of left forearm to fingers, like electric shocks; severe twitching pains like fleabites in several parts, requiring scratching, then disappearing; about 1 hour after dose rough dryness in throat; coldness on knee.
10 d. On March 13th, 1854, commenced proving of dilutions by taking 5 dr. of 15th. No symptoms. ON 14th, 6 dr. in morning Hiccup, not specially painful, disagreeable jerks; nausea in throat, as if on point to vomit, – for 2 – 3 hours. ON 18th, same. P. M., headache, pain quite internal, across base of brain between ears, not very severe, rather unpleasant. 23rd. – In evening, same. In morning, throat at back quite dry, with painfulness on swallowing, as in commencing catarrhal angina. This symptom was the more noticeable because it had been felt on former occasions when this dil. was taken in morning, but then ascribed to a cold. Each time it disappeared in an hour, after washing out mouth. In neighborhood of left nipple, on spot about 1 in. in diameter, deep in chest a raw pain, very keenly felt, increased by respiration and in proportion to depth of each inspiratory act, better soon after rising, and then wholly disappearing. P. m., urging to stool; passage of formed but not hard faeces was exceedingly painful, and must be effected with great caution, feeling being as if sphincter would be torn. On retiring to bed, still painfulness in anus. 25th. – In bed again
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.