Arsenicum

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14. Five grs. of arsenite of iron were given to a full-grown rabbit at 10 a.m. At 6 p.m. it became inactive and refused food. It continued in this state for 2 h., when it made violent muscular exertions, and was evidently gasping for breath, while it occasionally uttered a loud tracheal rattle. It died in a very short time. Larynx and trachea, as far as bifurcation of latter, much inflamed; lining membrane covered with a considerable quantity of mucus. R. lung morbidly red and less crepitant than natural; venous system gorged with coagulated blood; gastric mucous membrane covered with a layer of mucus, so solid as to adhere and peel off in parts with contents of stomach. Stomach much inflamed, especially about cardiac end, at which part there was some submucous extravasation. A second experiment produced similar results, minus those of the respiratory organs. (BRETT. Lond. Medorrhinum Gaz., xv, 220.)

15. Orfila introduced 50-60 grs. of orpiment (arsenious sesqui-sulphide, As2S3) and of realgar (arsenious sulphide, As2 S2) into cellular tissue of dogs. In all cases death ensued in about 2 d., with signs of gastro-intestinal inflammation. In one dog there was endocardial ecchymosis, and in another redness of lungs. (Journ. de Chimie, April, 1826.)

16. Wohler and Frerichs gave 3 grms. of pure arsenate of lime (calcarea arsenica) to a full-grown dog. At first it remained quiet, and after 2 hours showed no distinct symptoms of illness; next m. it was dead. Very liquid feces had passed off. Stomach contained about 20 grms. of a mucous, faintly-acid liquid, coloured yellow by bile, with numerous strongly-injected spots, and here and there ecchymoses of size of lentil. Mucous membrane reddened through whole intestinal tract, but nowhere the seat of destructive inflammation. (Chem. Gazette, vi, 228.).

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Richard Hughes
Dr. Richard Hughes (1836-1902) was born in London, England. He received the title of M.R.C.S. (Eng.), in 1857 and L.R.C.P. (Edin.) in 1860. The title of M.D. was conferred upon him by the American College a few years later.

Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.
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