Nosodes & Isopathy

While the classic homoeopathic medicines drawn out of the three kingdoms of nature are used for curing the similar symptoms seen in a patient the nosodes and isopathy, suit not only to the patient himself but also to the morbid states….

Q.1 Do you think that the Nosodes and Isopathic remedies should dominate over the wide field of Homoeopathic therapeutics?

The role of Nosodes and Isopathic medicines in Homoeopathy is CAPITAL. We may define the role in two words: SPECIFICITY and IMMUNITY. While the classic homoeopathic medicines drawn out of the three kingdoms of nature are used for curing the similar symptoms seen in a patient the nosodes and isopathy, suit not only to the patient himself but also to the morbid states.

Q.2 Should they be prescribed systematically in certain morbid states or only like other medicines?

It is necessary to make a distinction between Isopathy and Nosodes though isopathic remedies and nosodes are both made out of organic products.

The nosodes will always be applied, if possible, according to their indications set down by the law of similars. We should, therefore, use them like all other homoeopathic medicines, with reference to the Materia Medica, specially PSORINUM, MEDORRHINUM, SYPHILINUM, TUBERCULINUM, BACILLINUM ETC., that have a very wide pathogenesis.

As for the isopathic remedies, they are reserved for certain conditions when IMMUNITY is sought for, or when one wishes to turn a simple amelioration to a complete cure. This is why we will apply the isopathic medicines in the last phases of the treatment.

First published in Hahnemannian Gleanings, v. 7, No. 7, 1936. Note by the Editor-in-chief: A very interesting article on Isopathy and Nosodes was published in 1 `Homoeopathic Moderne of 15th March, 1936. We have got it translated by Dr. Rajkumar Mukerji of Chandanagar and published this issue. This article will create a new field of research amongst the homoeopathic fraternity all over the world.

IN THESE CASES WE SHOULD KNOW TO APPLY SYSTEMATICALLY THE ISOPATHIC PRODUCTS AND EVEN THE NOSODES. But what is most important is to know how to prescribe these two kinds of medicines at the OPTIMUM MOMENT, and above all not too soon. If not, some aggravations may ensue, that may be troublesome, sometimes very grave and dragging.

The rules for the use of Isopathic remedies are very excellently given in the book of Dr. Collet. They are always valuable, expecting some precisions given by time. Particularly, as for the nosodes, so far the Isopathics the practice of drainage, helps to avoid all very dangerous reactions and to obtain the MAXIMUM efficiency.

Q.3. What are the Nosodes and Isopathic medicines, that are more often used?

A. Diluted Microbian Cultures.

Generally, the conditions when the diluted and attenuated cultures are used, are still less known, or not well precised. It requires a precision in this chapter:

STREPTOCOCCINUM: It has a good relation to Pyrogenum, It has the same indications of Pyrogenum and may be utilized in puerperal fever, erysipelas, and in other streptococcic infections. It is better to apply it after Hepar sulphur with which it has a good relation. But according to my experience this remedy is not as useful as the other two.

STAPHYLOCOCCINUM should be applied in Osteomyelitis, furuncles, panaris etc. Results are not constant. Isopathic medicines made out of pus of the patient should be preferred to it.

PNEUMOCOCCINUM: It is very often used in high dilutions by Dr. Nebel and by Dr. Roux in acute pulmonary affections, pneumonia and in broncho-pneumonia. It seems that it gives excellent results (Pneumococcin M of the Pharmacy Boiron)

ENTEROCOCCIN AND COLIBACILLIN: Here are the cultures that I have applied several times in all possible dilutions in enterocolitie and in entero-renal syndrome. Results are inconstant and deceiving. I have abandoned them and preferred instead the isopathy of stool and urine, and above all the ANTICOLIBACILLARY SERUM of Vincent. However, it is necessary here to mention the INFLUENZUM of Dr. Nebel and his INFLUENZUM, ICE. Both of them contain numerous stocks of colibacilli and are very active.

TETANOTOXINUM. It is to be taken up and utilized, as Dr. Cahis is now doing, in all inveterate spasmodic affections (but in tetanus Dr. Cahis has shown that it fails.).

PYOCYANIUM. It has been applied with interest in acute poliomyelitis and in its sequelae. Results are very inconstant.

DIPHTHEROTOXINUM. It ought to be applied according to the practice of Dr. Cahis in affections either acute or chronic, besides diphtheria, but always caused by it. Let us recall here that Dr. P. Chavanon used Diphtherotoxine 4m to 8m as preventive of Diphtheria, with negative reaction of Schick in course of the use of this medicine.

NOSODES OF BACH. After having been preached in England, they have not fallen into oblivion. But, however, Wheeler, Dishington and several others have got good results in their practice with them. The pathogenesis of these remedies appeared in the British Homoeopathic Journal (Dysentricus, Morgan). The first authors, becoming enthusiastic, thought that they have got the nosodes and the real factors of psora. They applied these medicines according to plus dosage (30 first, 31 on the second day, 32 on the third and so on) All the microbes of the dysentery were thus utilized not only in dysentery but in all sorts of morbid conditions. The latent psoric poison according to that theory accompanies some intestinal troubles. “When the skin, the excretory organ per excellence, does not perform its function, the intestine substitutes it” (Leon Renard). Dr. Bach found in the stools of the persons suffering from latent psora some bacilli having the property of hindering the fermentation of lactose. In a few days these micro organisms vary, disappear, or reappear. Very often, the symptoms aggravates at the end of the period when the germs disappear from the stools and ameliorate when these bacilli are in maximum intensity in their positive phase of reappearance.

The nosodes of Bach thus applied are: Dysentricus, Morgan, Gaertner, Proteus, Coli mutabile, Faecalis alkaligenes (this last one is polyvalent)

My friend Dr. Leon Renard and myself have obtained with these nosodes of Bach some incontestable successes, in certain cases of eczema and psoriasis.

B. Diluted serums.

Very little utilized since the last few years by Homoeopaths, the serums diluted and dynamised, have become a new group of remedies of the first importance in our arsenal of therapeutics. The remedies are not yet used anywhere but in France, but we hope that our colleagues of foreign countries will give their attention to the utility of these medicines.

The works of Dr. Martiny on the immunity have clearly shown the importance that should be attributed to the applications of serums.

ANTICOLIBACILLARY SERUM: It is a wonderful arm in the treatment of colibacillosis. I use it in every acute stage: Pure serum by rectal injection, 10 centicubes a day.

Subacute stage: 1x either by rectum (30 drops with 10 centicubes of physiological serum or by mouth 10 drops three to four times a day).

CHRONIC CASES: Very grave urinary colibacillosis (30 drops with 3x by mouth, 5 to 10 drops a day. The same treatment as in the subacute stage.

But above all, we use at the same time the medium and higher dilutions of serums. When the ponderable doses and the lower dilutions as medicines of drainage act on the elimination by the bladder and the stools, the higher dilutions act against the neurotrope toxins of colibacilli (considerably act in fatiguing states, loss of power of work and psych-asthenia). Serum Anticolibacillary will be applied in the 30th, every day or every third day, then 200th and 1,000 Korsakoff, alternated or associated with Thuja 200 or 1000.

ANTISTAPHYLOCOCCIC SERUM I have used it with success in furuncles not in the acute stage but to check the return of the suppurative process. Dilutions: 30, 200, 1000K.

Antipneumococcic serum: I have no personal experience. It is to be tried.

Antistreptococcic serum: I have no personal experience of it. It is to be tried.

Antidiphtheric serum: It hardly gives any good result even in diphtheria. Mercurius cyanatus is to be given instead and other classic homoeopathic remedies on the one hand and we prefer on the other hand the pure antidiphtheric serum which should be applied by mouth. But Dr. Barishac has shown that Antidiphtheric serum 200 is an excellent remedy in relapsing urticaria. All the horse serums act, All the horse serums act, according to the law of similars in urticaria. Serum Antidiphtheric is perhaps more useful.

SERUM D’ ANGUILLE (Eel serum). Truly speaking it should be considered not like a nosode directly indicated according to the law of analogy, like Lachesis, or other poisons, and other products drawn out of animal kingdom. It was discovered by Dr. Pierre Jousset, who gave its first pathogenesis. Serum d’ Anguille is a remedy of choice in acute nephritis. Late Dr. Picard presented last year in the congress of Budapest, an excellent communication on this remedy which is worth reading. Dr. Arthus, collaborator of Dr. Picard, made some instructive experiments on this remedy in the laboratory of l’ Hospital Saint. Jacques. In my personal practice, Serum d’ Anguille has given extraordinary good results in the treatment of albuminuria even chronic. Perhaps in future, it will not be applied only in 3x dilution as it has become classic since the time of Dr. Jousset, but I hope that it will be applied in the high dilutions, such as I have begun. According to my opinion Serum d’ Anguille ought to be considered as one of the most important remedy of our Materia Medica.

Antipest Serum of Yersin: Proposed by Dr. Barishac, for the treatment of grave or atypical forms of influenza. This remedy is proved useful in 6, 30. In future its indications are to be precised as well as that of Hafkine’s Antipest vaccine.

ANTIDYSENTERIC SERUM: Less used by homoeopaths. The antidysenteric serum will be a priori a useful arm in the treatment of enterocolitis. The researchers who have already acquired experience by the use of Nosodes of Bach are to be consulted.

The different stocks of Bacteriophages are also interesting to use for the homoeopaths. They should be grouped in our Materia Medica by the side of Nosodes and Isopathics.

C. Nosodes.

Some of the nosodes have been widely studied by homoeopaths. Some well known pathogenesis have been included in our Materia Medica. These remedies are applied, no more in the sense of specificity and immunity but with the strict regard to the laws of Similars.

PSORINUM MEDORRHINUM SYPHILINUM BACILLINUM TUBERCULINUM In order to know the pathogenesis of these remedies we should read the books on Materia Medica particularly of Hering, Allen, Farrington, and sometimes kent (?) and Nash. (A new book) “Nosodes and biotherapics” by Dr. O. A. Julian. (R. M.)

Thus Psorinum is a valuable arm; of course, schematically it is the ancient Sulphur becoming “cold”. But we know nothing of its possibilities in persons infected with “itch”. If we happen to meet such a patient we will treat him with the local application of sulphur, like all other doctors. We will not consider the mentality of such a person infected with the itch poison as Hahnemann himself did. Now, Psorinum should be applied for a long time, after the disappearance of “Itches” even to the descendents of such patients.

As for Medorrhinum and Syphilinum practice shows that they should be applied with regard to the law of similars systematically. But how difficult it is to be settled thus in practice. In a general way these remedies, in high dilutions do not often act in acute and recent infection. On the contrary they are very important in the chronic and in the hereditary states. Thus Medorrhinum prescribed long time after the disappearance of Gonorrhoea, or even in nursing child, who suffers from erythema of the gluteus, without knowing whether the medicine has acted, because the child is impregnated with hereditary toxins or for other reasons.

As regards Syphilinum its action has been shown to be very often inconstant. So a whole gamut of this product is used: Syphilinum classic (scrapings of indurated chancre), then Hepato-syphilinum and Rachi-syphilinum recommended by Dr. Barishac (the first the infected liver of the new born, the classical antigen; the second is the liquid containing in the cephalo-spine, when the subject is attacked with the disease.) We apply also Syphilinum P, a mixture of the different dilutions of the same stock. Thus there is a group of Syphilinums for being adapted homoeopathically to the different categories of the diseases of the patients. Thus in secondary and in tertiary syphilis an incontestable result is obtained.

1. TUBERCULINUM T. K., SERUM OF MARMORECK IMMUNISED BODIES OF SPENGLER, VAUDEMER, BACILLINUM, TUBERCULINUM BOVINUM, Filtered BACILLUS OF DENYS B.C.G. (at present called V.A.B.) AVIARE, PISCIARUM etc. The tuberculous conditions are legion. Their identification with the Psora of Hahnemann, has obliged us to consider the use of the Tuberculines not only in tuberculous subjects and in subjects clearly predisposed to the tuberculosis, but also in Scrofula, in Arthritis, in the different categories of Anaemic subjects, demineralisation and even in numerous patients suffering from perturbations-endocrinal, functional or sympathetic.

But the art of therapeutics consists in applying in the proper time and in the optimum dose, after well appropriated drainage, the properly selected tuberculine, which is often very difficult. Let us recall here some general rules of the administrations of these nosodes.

Begins to give the patient a ground remedy or a constitutional remedy, once or many times.

2. Follow the ground remedy by some functional remedies of drainage indicated by the symptoms of the patient.

3. Wait at least for two months to begin to prescribe tuberculins, and begin with the medium dilutions before entering into higher dilutions.

4. Do not repeat, but rarely, the dose of Tuberculines; wait two to three months or more.

5. The basis of repetition and choice of dilution should rest on the collective general state of health of the patient.

At present the use of Tuberculinum, T.K. is well-known. Dr. A. Nebel has given to us the pathogenesis of T. K. There is a good pathogenesis of Tuberculinum Bovinum in the Materia Medica of kent. Burnett’s pathogenesis of Bacillinum is the best. For the other products one should refer to his own experience; much groping is inevitable. Let us recall here the rule of application of Dr. Nebel.

Marmoreck (called Xylin) suits to pulmonary tuberculosis in evolution and to oxygenoid tuberculinic types whose defense reactions is bad.

T.K. (Tuberculinum of koch also called Phenol K.) suits to oxygenoides of better defense. (should be used prudently)

Denys suits to certain tuberculous patients with florid look, and to hydrogenoid tuberculinics.

T.R. (Residual tuberculine) suits specially to tuberculinics of adult and of ripe age, carbonitrogenoid.

Pertussin or Coqueluchin (expectoration products and nosodes of whooping cough) which we owe to the English homoeopath Clarke, is an excellent medicine. But is should not be used immediately. In the treatment of Whooping cough this is how I proceed generally: I begin with Sulphur 3,, which may either abort the disease, or make it of short duration hastening the period of action. The child expectorates sooner. After a first dose of Sulphur, the appropriate remedies are indicated, repeated frequently: Belladonna, Drosera at the beginning, then Ipecac, Antimonium tartaricum, Cina, Cuprum, Corallium rubrum. Coccus cacti, etc. Besides these remedies I alternate every 5 days in the evening Pertussin 30 and Sulphur 30. At the end of whooping cough I give Pertussin 200.

In some epidemics, the habitual Pertussin does not act, an isopathic is prepared, either auto-Pertussin with the proper products of expectoration of the diseased child.

Malandrinum, little used, gives some interesting results in some chronic eruptions on palms and soles of the feet aggravated in cold seasons and by washing. It is a complementary of Sulphur, of Psorinum, of Petroleum for these eruptions and also of Thuja and Silicea for the bad effects of antivariolic vaccination.

HYDROPHOBINUM (or Lyssin, the saliva of rabid dog) it is used in mental diseases, delirium with hydrophobia or with priapism. I have obtained good results with this remedy in dysphagia with spasms of the pharynx and oesophagism. It would also be interesting to use also the marrow of the rabid dog, taken new in the furies of maniacs or in delirium tremens.

PYROGENUM is one of the very useful arm in our arsenal for the treatment of septicemias and even of phlegmons, abscesses, panaris, for avoiding and stooping suppurations. The stock of Paul Chavanon seems to be particularly useful.

VARIOLINUM VACCININUM VARICELLINUM are nosodes interesting to consider in the treatment of diseases with pustules, acute or chronic. One should not stick to the specificity, but should apply them according to the law of analogy.

Variolinum is to be specially mentioned. We know that it is useful for the preventive treatment of small pox. Used in the 30th dilution every day during one month, it seems to cause an immunity though temporary, against small pox. It is probable that by using high dilutions one may obtain a durable immunization. On the other hand I have had a marvellous result with this remedy alone, Variolinum 30 prescribed in a tubercular lupus, in patient who came for my consultation in the Hospital- Bellan.

As for Scarlatinum, Morbillinum the nosode of Zona, I have no experience for speaking about it. They are useful to use either preventively or preferably in a patient for the sequelae even very distant, of the corresponding diseases.

INFLUENZINUM. There remains to consider this interesting remedy as a preventive and curative of Influenza and for the sequelae of this dangerous disease.

We now possess thanks to A. Nebel, a complete group of this nosode.

Let us mention here this group:

Influenzinum habitually used.

Influenzinum of A. Nebel 1936 (carrying the date of the year in course, stock of numerous products of expectoration with numerous stocks of colibacilli and many homoeopathic remedies.)

Influenzinum I.C.E. (influenza, colibacilli, encephalitis). This remedy has been very successfully used by Dr. O.A. Julian. Unfortunately it is no more prepared in France (R.M.)

Influenzinum I.C.F.S. (Influenza, colibacilli, encephalitis, staphylococcus.).

Vaccine E. (special preparation for influenza, injectable).

Encephalitis: By sub-cutaneous injection and by mouth.

These remedies are used not only before and during Influenza; but also after influenza, specially when the disease seems to be torpid, with very little temperature, and is followed in cases of the menace of sclerosis or specially for the post-influenza Parkinson’s syndrome.

D. Isopathy Properly Called.

I often use isopathy of urines, blood, pus and of the phlyctenular liquid.

Urine. Isopathy of urines gives excellent results specially in renal calculus and in pyelonephritis. It is also interesting to use in diabetes. In the latter case, one may not only prescribe some dilutions of the total urine but also the dilutions of glucose extracted out of his urine as recommended by Dr. Barishac.

In colibacillosis with entero-renal syndrome, isopathy gives remarkable results as recommended by Dr. P. Kollitsch.

Blood. After having treated some cancer and precancer subjects by blood isopathy, Dr. J. Roy abandoned this practice. Afterwards he has tried to give to the patient not the dilutions of glucose extracted out of his urine as recommended by Dr. Barishac.

In colibacillosis with entero-renal syndrome, isopathy gives remarkable results as recommended by Dr. P. Kollitsch.

Blood. After having treated some cancer and precancer subjects by blood isopathy, Dr. J. Roy abandoned this practice. Afterwards he has tried to give to the patient not the dilutions of his own blood, but the dilution of the blood of a young subject having ideal health.

However, one obtained in some cases of cancer, and specially in the arterio-sclerous and persons suffering from migraines, some incontestable success by giving to the patient the dilutions of his own blood. As for me I still continue this isopathic method, specially in cases of in of inveterate migraines.

Let us recall that Roger in Chicago, Licinio Cardoso at Rio de Janeiro, use blood isopathy specially in chronic cutaneous affections, specially in eczema. The Brazilian school still continue this practice.


Habitually the dilutions 30, 200, 1000 and 10,000 Korsakoff are used. The lower dilutions aggravate.

Blood isopathy would give some good results in cases of some fevers and in epidemic fevers, specially in measles and in acute articular rheumatism according to Dr. Collet.

Menstrual blood: Following Dr. Dano I have begun to use the isopathy of menstrual blood (dilutions done with the blood collected on a compress, preferably of the first or of the second day).

Saliva: The homoeopaths of modern times should not neglect to use isopathy of saliva, so easy to prepare. Dr. Collet used it frequently in gastric embarrassment, the pituites, in dyspepsia, and in constipation, metritis, rheumatic pains, lumbago, paralysis of the 3rd and the 7th pairs and even in oxyurias etc. Personally I have no experience in this method.

Cephalo-rachidian liquid: This may be used in meningitis (chronic, syphilitic) and in the organic cerebro-medullar lesions. In multiple sclerosis, some good remissions are sometimes obtained following this method of therapeutics. It completely fails in the Parkinson’s disease.

Stools: The isopathy from stools may be tried in parasitosis, colibacillosis, and in different intestinal affections.

Bronchial secretions: This isopathy is useful in Asthma and specially in bronchorrhoea, chronic bronchitis, chronic gangrene, bronchial dilatation. Finally it is useful in some cases of gave forms of bronchial tuberculosis. The results are often unexpected on condition alone if the dilutions used are medium or higher. The lower dilutions seem to be inactive and cause aggravation. Sweets and products of cutaneous excretions: Very good results are obtained in cases of chronic cutaneous affections.

Tears and nasal discharges: Dr. Collet used frequently the isopathy prepared from tears of the patients suffering from grave conjunctivitis, ulcerous keratitis and other ocular affections.

Mauritius Fortier-Bernoville
Mauritius (Maurice) Fortier Bernoville 1896 – 1939 MD was a French orthodox physician who converted to homeopathy to become the Chief editor of L’Homeopathie Moderne (founded in 1932; ceased publication in 1940), one of the founders of the Laboratoire Homeopathiques Modernes, and the founder of the Institut National Homeopathique Francais.

Bernoville was a major lecturer in homeopathy, and he was active in Liga Medicorum Homeopathica Internationalis, and a founder of the le Syndicat national des médecins homœopathes français in 1932, and a member of the French Society of Homeopathy, and the Society of Homeopathy in the Rhone.

Fortier-Bernoville wrote several books, including Une etude sur Phosphorus (1930), L'Homoeopathie en Medecine Infantile (1931), his best known Comment guerir par l'Homoeopathie (1929, 1937), and an interesting work on iridology, Introduction a l'etude de l'Iridologie (1932).

With Louis-Alcime Rousseau, he wrote several booklets, including Diseases of Respiratory and Digestive Systems of Children, Diabetes Mellitus, Chronic Rheumatism, treatment of hay fever (1929), The importance of chemistry and toxicology in the indications of Phosphorus (1931), and Homeopathic Medicine for Children (1931). He also wrote several short pamphlets, including What We Must Not Do in Homoeopathy, which discusses the logistics of drainage and how to avoid aggravations.

He was an opponent of Kentian homeopathy and a proponent of drainage and artificial phylectenular autotherapy as well.