Sulphate of Cinchonine. (C19H22N2O) H2SO4.
Clinical
Amblyopia. Constipation. Diarrhoea. Epistaxis. Fever. Hair falling off. Headache. Heartburn. Sexual excitement. Spinal irritation. Urinary disorders. Veins distended.
Characteristics
*Cinchon. *sul. has been extensively proved, but it appears to have been little used in practice, from having been over-shadowed by the better known alkaloid, *Chinin. *sul. The general outline of symptoms is the same in both. Some of the most peculiar symptoms of *Cinchona *sul. are the following: Bursting headache on waking. Pain in anterior lobe of cerebrum, as though a net were drawn through the whole substance of the brain. Darkness before the eyes on exerting them. Sensation as if the throat were burnt with hot drink. Cold feeling at pit of stomach. Pasty taste, and pasty stools. The sexual organs are excited: voluptuous dreams and painful erections at night. Menses a week too soon and more copious than usual. The chest seems hollow and distended so that breathing seems especially easy. Many symptoms of fever are present, and there is recurrence of symptoms. Sweat between shoulder-blades in the night, followed by itching. Symptoms worse after eating, by motion. Weariness, sleepiness, general aching, especially in eyes, ears, and genitals.
SYMPTOMS.
Mind
Sort of transient intoxication, complete disinclination for work.
Head
Confusion in head with pressure in eyes. Morning head-ache, bursting headache on waking. Pain in anterior lobe of cerebrum as though a net were drawn through the whole substance of the brain. Profuse falling out of hair. Tension in scalp, with soreness at roots of hair, as if there were pus under scalp (mostly right).
Eyes
Accumulation of mucous before eyes. Attacks of darkness before eyes, on exerting them.
Ears
Roaring in ears, during the night.
Nose
Sudden nose-bleed of thin, bright red blood while sitting.
Mouth
Ptyalism, especially in forenoon.
Throat
Sensation as if throat were burnt with hot drink, and something were sticking in pharynx. Sticking pains in throat, as with fine needles, on swallowing.
Stomach
Sudden heartburn. Pains at pit of stomach worse by pressure. Great heat in stomach, extending into abdomen, and up into chest, throat, and head, especially in throat, with burning thirst. Cold feeling at stomach, fulness, pressure, throbbing, sensitiveness.
Stool and Anus
Dull cutting in anus, extending thence to navel, with fine stitches in pit of stomach. Pasty diarrhoea. Constipation, hard, scanty stools with tenesmus. Pasty stool passed slowly with much pressing, sphincter very much relaxed, while the rectum is more contracted than usual.
Urinary Organs
Burning sensation in urethra after passage of urine. Excessive urging. Urine thick sediment, brownish green, dark red, reddish yellow, white. Iridescent film.
Male Sexual Organs.
Great excitement, erections.
Female Sexual Organs.
Menstruation a week too soon and much worse than usual.
Chest
Chest seems hollow and distended so that breathing seems especially easy. Stitches mostly extending from right side to pit of stomach at insertion of diaphragm. Pressive pain under sternum, waking in night it seems as though lower portion of sternum were pressed inward.
Neck Back and Limbs
Painful stiffness of neck, worse moving it. First dorsal vertebrae painful to pressure. Trembling of limbs and weakness. Pains, drawings, bruised sensation.
Generalities
Periodic sticking pains in chest, better standing or sitting, worse lying or during deep cough.
Sleep
Sleepiness. Quiet sleep without dreams, but without being refreshed. Voluptuous dreams and painful erections.
Fever
Chilliness. Shaking chill 10 a.m. to noon without subsequent fever or sweat. Burning skin. Great heat of body with turgescence of veins (evening). Heat of head with cold extremities. Sweat with excessive thirst in night. Skin dry, veins distended. Sweat between scapulae at night, followed by itching compelling him to scratch.
