8 b. Aug. 7th, all functions being normal, took 100dr. at 12 m. with no effect during rest of day 8th. – At 6 a. m. sharp cutting pain in right ovarian region, extending about hip and down thigh, awoke me. Could not find any position comfortable. Head ached violently through temples and on vertex. Top of head felt as if uplifted. Loud ringing in right ear. On lifting head very dizzy and somewhat nauseated. Dyspnoea great. Feared I should lose my breath entirely. Had hardly courage enough to take any more drug, but did at 10 a. m. take 100 dr. Symptoms all increased. Was unable to rise. Very chilly, though day was quite warm. Abdominal pain grew worse. At 12:30 p. m. menses appeared 2 day in advance. Headache increased; pain in abdomen almost unbearable, though somewhat relieved by heat. Abdominal pain not continuous; intervals between attacks almost regular – about 10 m., and spasm lasted 5 m. L. side numb, back of neck same; face flushed; eyes twitched, and pupils were dilated. Everything looked blue. Very cross and hungry; but food increased nausea, while water relieved it. At 2 p. m. chill, which lasted about 5 m., attended by great nausea and vomiting. At 3 p. m. temp. 99 5, pulse 96. Abdominal pain so agonizing I could hardly endure it. About 6 p. m. symptoms abated, and I fell asleep, but was restless all n. 6th. – Awoke with dull pain in right ovarian region and frontal headache, with a little dizziness. Limbs ached. L. side felt numb, especially left foot. Flow profuse. So unwell I could not take any more drug. 10th. – Still very weak and tired. Flow profuse, but ovarian pain slight. Head felt mixed; it seemed entirely void of ideas. It was an exertion to try to think. Throat ached, and dyspnoea came occasionally. 11th. – Flow abundant, I felt tired. 12th. – Flow less. 13th. – Flow disappeared, but left white leucorrhoea. 14th. – Felt well. Leucorrhoea less, and no traces of it on 16th.
8 c. No symptoms from 16th until 28th, when at 9:30 a. m. I took 10dr; 29th, at 3 p. m., 25dr.; 30th, at 11 a. m., 50dr.; and 31st, at 11 a. m., 50dr. First symptom occurred this day about 2 p. m. Temp. normal, pulse 76. Dull frontal headache, loud noise in right ear as of a valve continually opening and shutting. Somewhat sick at stomach and dizzy. At 5 p. m. sharp, cramp – like pain in left inguinal region, which increased until 7 p. m., when menses appeared 5 day early. For about an hours pain seemed better, but after that began with renewed violence, worse than in two former provings. Thought I could not get enough air into lungs, inspiration was so difficult. About 10 p. m. fell asleep, as pain had abated. Sleep was restless, being interrupted by several attacks of dyspnoea. Sept. 1st. – On rising was very dizzy, sick and chilly. Throat felt as if in a vice. L. side numb. It seemed in walking as if floor were soft like wool. Arms felt better from being twisted. Pain, rather of a dull character, extended from nape of neck to right shoulder – blade. Pain in left ovarian region intense, not a constant pain; it began feebly and gradually increased, dying in same manner. All d. I felt something bad might happen. About n. headache and abdominal pain subsided, and I felt well. 2nd. – On awaking, whole body numb, especially left side. Felt great desire to inspire, but was unable to get sufficient air. On rising very dizzy. Tongue had heavy white coat. Joints seemed loosened. Everything looked blue, and there was loud ringing in right ear. At 8:30 a. m. took 60 dr. 8:45, had slight chill, accompanied by death – like nausea; soon followed by vomiting of thin white mucus, after which felt better, though very tired. Arms felt as if they had carried heavy weight, legs very weak. It was an exertion to talk. Flow very abundant, abdominal pain slight. 3rd. – At 7 a. m. took 150dr. At 8 a. m. ate good breakfast. In about 1/2 hours great nausea, and I soon vomited all the breakfast. At intervals all day dyspnoea great, muscles of back seemed tired, and I ached all over. Limbs heavy, and occasionally left side numb. Pain in head better, roaring in both ears troublesome. Throat ached. It was tiresome to talk, and voice sounded hoarse. Flow profuse. 4th. – In m. felt better, and took at 10 a. m. 100 dr., but vomited it all in a few moments. No headache. No abdominal pain, though flow as abundant as day before, and I felt very tired all day 5th. – With exception of occasional attacks of suffocation, and great weakness of lower limbs, felt well. Flow about the same. 6th. – Very tired. Flow less, and continued to decrease till 10th, when it ceased. 13th. – White thin leucorrhoea, which lasted 2 d. Only slight variation from normal was anticipation of menses, once on 26th Sept., the other 22nd Oct., which seemed more abundant than usual, though no pain.
8 d. Fourth and last trial of drug was made on 3rd Nov., at 8 p. m., when I took 100 dr. Shortly after stood about 1/2 h. On sidewalk to watch procession, and ground seemed damp; this may have modified proving somewhat. 4th. – At 10 a. m. unable to inspire freely; dull headache in frontal region: slight nausea. In walking, very dizzy. L. arm numb. Throat ached. Loud ringing in left ear. At 2 p. m. took 60 dr. About 4 p. m. dull pain in back of neck. Lower limbs ached, particularly at articulation of knee – joints. Dyspnoea marked. During evening pain in neck increased; whole head ached, particularly through temples. Head felt dropping in pieces. If I sat up, felt as if floating through air; if I lay down, as if sunken deep in bed. Objects near seemed a long way off. 5th. – On rising dizzy, and head ached violently through temples and on vertex. Noise in both ears and numbness through all limbs. Nausea slight. Dyspnoea noticed several times. At 7 p. m. took 75 dr. Symptoms all increased, in addition there was dull pain in left ovarian region, and back of neck was rather stiff. Awoke several times during n., and always with sense of suffocation. 6th. – At 8 a. m. took 145 dr. Headache intensified, dyspnoea great, and neck stiff all m. About noon abdominal pain increased. At 2 p. m. chill and great nausea; chills lasted about 10 m. Neck very painful; pain extended into right shoulder and down back. Difficult to turn neck to 1. At 2:30 p. m. another slight chill, with nausea. Headache and abdominal pain increased; latter greatly relieved by heat. Flashes of blue light before eyes. Everything looked far removed. At 6 p. m. aconite was given, and repeated every 15 m. till 5 p. m., with no relief. At 10 p. m. took 1 teaspoonful of tinct. camph. mixed in proportion of 5 dr. to 10 tablespoonfuls of water, and in about an hours fell asleep. 7th. – Pain in head somewhat better. Neck easily turned. Abdominal pain about same till noon, when it began to grow better. Camph. every hours throughout d. Suffocation at short intervals. Pupils dilated. Throat felt as if clutched. Milky – white leucorrhoea. 8th. – Very tired. No pain. Limbs occasionally numb, and I was dizzy in walking. Some suffocation, with feeling of heavy weight on chest. Leucorrhoea was not much. 9th. – Felt pretty well. 10th. – Well. No symptoms.
Throughout last proving urine seemed increased in quantity. Bowels not affected at any time. Menses up to Jan., 1885, anticipated 3 or 4 d. In Dec., 2nd day previous to menstruation, milky – white leucorrhoea, not profuse. Otherwise usual health. Appetite excellent all the time. (Ibid.).
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.