7 b. Nov. 3rd. – Seemingly in perfect health except cough, which had continued, at 10 a. m. took 50 dr. Dyspnoea was marked in 15 m., with sharp cutting pain in lower portion of right lung. cough continued and became more frequent, with scraping sore feeling under sternum; seemed more spasmodic, recurring at almost regular intervals of about 20 m., and was of a voiceless stifled character. Towards evening same headache began to return, and the peculiar stiff feeling in back of neck, so that involuntarily I put my hand constantly there to try and relieve by pressure. Cough continued, and during each attack I felt sharp pain in lower portion of lung. 10 p. m., 80 dr.; went immediately to bed. Slept very heavily till 4 a. m., though dreaming constantly; was waked at this time by bad coughing spell, lasting several moments. Head aching severely, eyes bloodshot an heavy, with red burning eyelids; back ached whole length of spine; face flushed, but body cold. At 5 a. m. temp. 98.6, pulse 92. On attempting to rise was seized with vertigo, felt as if falling forward, everything became black, and I grasped for support; this was accompanied by nausea, which prevented my eating breakfast, and 20 m. after I vomited coffee and toast which I had succeeded in taking. 10 a. m., 120 dr. Dyspnoea immediately, marked with severe coughing spells occurring at intervals of 10 m.; aphonia and pain in lower part of right lung on deep inspiration or coughing. Pain in back became very severe, and was localised! in cervical and upper portion of sacral region. 12 m., cough continued, and on attack of pain in region of heart as in previous proving. Vertigo as if falling forward, with black spots dancing before eyes, and in going up and down stairs felt as if I were stepping over too far and should fall. Cough aggravated by exposure to cold; ameliorated in warm room; not especially painful except as it caused pain in lungs, which lasted several moments after each coughing – spell. 4 p. m., urgent stool at 1 p. m. and another at 3, small, watery, dark, and offensive; no pain accompanying, but severe burning in rectum and anus following. Temp. 100; pulse 110. Very thirsty and drank large quantity at a time. 10, 200 dr. In 5 m. urgent stool; same colour and consistence as before, and same burning pain following. Every inspiration an exertion, and very unsatisfactory, as deep breathing brought on pains in lower part of right lung and in heart. Cough almost constant, unless in very warm room. Head and back ached; neck stiff; carotids throbbed. Pulse 130; temp. 103 at 11 p. m. Constant dyspnoea; respiration 36. Frequent urination, once in 3 hours l scanty and high coloured; sp. gr. 1025. 5th. – Very restless n., with frightful dreams of being killed or burned; bright images before eyes, which were sensitive to light, with dilated pupils, and bloodshot. Constant and increasing sense of constriction across chest, as if I had been running fast and long, or as of heavy weight on chest. 5 a. m., movement of bowels, followed by same burning and stinging, and slight haemorrhage as from piles. Cough not quite so frequent or painful; dyspnoea continued, with same oppressed feeling in lung. Head and back ached; was perfectly exhausted and very weak. No appetite, but very thirsty. Temp. at 7 a. m. 101.2; pulse 120. Coccyx seemed elongated, was extremely sensitive to pressure, and ached all the time; could not sit except on foot or air – cushion, to raise it from chair. Dragging pain in lower part of pelvis and back. 11 a. m., severe aching pain in right ovarian region, causing me to forget all other pains, and walk and floor. Pain constant, radiating from right ovarian region to hip, thigh, and back, with occasional shooting darting pain, causing me to hold my breath, and at same time leucorrhoea, coming with a gush, of milk – white colour, coming at no other time. This lasted till 4 p. m., when it ceased suddenly, and from that time back and head began to feel better. Two movements of bowels at 10 and at 3. 6th. – Had more comfortable night; cough less frequent; dyspnoea not so decided, although oppressed feeling still present. Felt weak and exhausted, but better appetite. Back and head still ache. Temp. and pulse normal. Frequent urination – 30 oz. in 24 hours; sp. gr. 1030; acid reaction. Only 3 movements in a day, but still somewhat loose and excoriating. 7th. – Am feeling well again. Head rather weak, and slight cough remains.
The drug seemed to have no long – continued effect; unless the fact that in this month the menses again anticipated nearly a week, with increased flow, be attributed to this. ( Publ. of Mass. Hom. Society, 1885.)
8. a. LUCY JOHNSON PIKE. The following proving was made upon myself under the direction of Dr. Southwick. My weight is 175 lbs.; height 5 ft. 4 in.; hair light brown; eyes blue; normal pulse – rate 80; resp. 16. At the time the 1st dose was taken I was 25 years old. Health has always been good, with exception of an attack of diphtheria in 1878, which yielded readily to the similimum, and left no chronic lesion. All functions being normal, took first dose of 10 dr. at 7:45 a. m., June 20th, 1884. Pulse and temp. remained normal, and no symptoms appeared throughout day 21st. – 10 dr. at 7:45 a. m., and again at 12:45 p. m., with no variation in health. 22nd. – No rug taken, and no symptoms. 23rd. – 20 dr. at 7:15 a. m., and again at 12:45 p. m.; no drug symptoms 25th. – At 12:45 p. m., and again at 3:30 p. m., 25 dr. About 6 p. m. a sudden and violent pain over right eye, accompanied with boring through temples. Pain soon spread over whole head. Heavy pressure on vertex. After this had lasted about an hours, vision blurred as if eyes were looking through blue lace; nausea and dizziness marked, as well as loud noise resembling a windmill, in left ear. About 12:30 p. m. pains abated. 26th. – At 4 a. m., having slept about 3 hours, nausea seemed to wake me. No relief on rising, in fact worse and giddiness prominent. At 8 a. m. pain seemed to have gone, although nausea still remained, and occasionally noise in left ear was marked. 9:20, slight nose – bleed. 11 a. m., 25 dr. Symptoms not aggravated, with exception of noise in left ear, which lasted about a. m. at a time. At 12:45 p. m. 25 dr. Nausea increased. At 3:45 p. m. 25 dr. 4:30 p. m., nausea and giddiness, so that I was obliged to go to bed. Violent pain in head returned, still worse over right eye. No position comfortable. Faintness spread over whole body. Glass of ice – water and cracker taken with relief. About 10 p. m. pain subsided, and I slept till 11:30 p. m., when a dram of suffocation awoke me. On rising, dizziness not so much felt, but general sickness, head sore to touch; I did not care if I lived or died, and decided not to take a drop more if I ever felt better. 27th. – At 5 a. m., after sleeping about 4 hours, throat felt dry, and voice was hoarse. Occasionally pain in head, but nausea and giddiness less. Tongue had a yellow coating. Glass of ice – water relieved all symptoms. 8:20 a. m., nose – bleed, more profuse than before. 12:30 p. m., feeling better, took a little lunch, which brought on nausea again. 1:30 p. m., 30 dr., with no aggravation until 4 p. m., when there was sharp and sudden pain in right ovarian region, which later radiated down thigh and across left hip, relieved by lying down and flexing thighs upon abdomen. Head dull and heavy; I could not walk straight or upright, abdominal pain was so intense. Throat seemed to be clutched. Hoarseness gone. Temp. and pulse were up to this time normal, but at 9 p. m. pulse 64 and temp. 99. 10:30 p. m., 30 dr. Sleep almost immediately followed. I dreamed that throat grew up, and awoke in fright, finding it very difficult to breathe. I was trembling violently, and left arm was numb and heavy. (The numbness of the arm I have felt before, and the position in which I lay, on the left side, may account for it.) Nausea great; but it was easy to walk, except that I could not get over thought that I was suffocating. In about an hours fell asleep, and did not wake till 6 a. m. 28th. – Throat painful to touch and voice a little hoarse. Nausea present. Head felt big, and eyes could not bear light. Pulse 68, temp. 99.5. Pain in abdomen gone. Milky white leucorrhoea. Tongue had still a thick yellow coat. Felt better after eating breakfast, but was very tired all m. In afternoon I went to walk. About 4 p. m., while out of doors, an indescribable sensation came over me. I really thought I was dying. Whole body seemed falling in pieces. Atmosphere appeared blue, and there were constant flashes of light before eyes. Could not walk straight. Occasionally noise in left ear was noticed, but it seemed this time like a loud bell ringing at a distance. My body felt as though it were elastic and stretched itself out. Tongue seemed alternately to expand and contract. Ice – water relieved nausea. L. side numb. On lying down symptoms were better, and at 10 p. m. I fell asleep, awaking in about an hours with a sense of suffocation, which soon passed away. 29th. – At 6 a. m. pulse 72, temp. normal. Tongue still coated. Head felt large, and there was pressure on vertex. Occasionally disturbed by ringing in both ears. Nausea had gone, and I felt unusually hungry. Leucorrhoea profuse. About 4 p. m. irresistible sleepiness came over me, and I slept from then till 7 p. m., awaking simply long enough to eat a bountiful supper; and again slept with slight interruption till 7 a. m. 30th. – Pulse 72; temp. normal. Throat dry, and it required great exertion to talk; all food very acceptable. Leucorrhoea still abundant. Head sore to touch. July Ist. – Pulse 78; temp. normal. Tongue still a little coated. No leucorrhoea, but pain in sacral region normal. About 6 a. m. a little frontal headache with slight nausea. 3rd. – Tongue almost clean, and no leucorrhoea, though I felt tired all day 4th. – Felt quite well. No more symptoms arose from proving. Sp. Gr. of urine varied from 1015 to 1019. Bowels not affected. Menses appeared 2 day early. Remained perfectly well from 4th July to 7th Aug.
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.