11b. Three months later (March 1st, 1870), feeling quite well, I took at 11 a. m. 10 dr., and at 2:30 20 dr., followed in 1/2 hours with eructations tasting of drug, and increased flow of urine. At 8 took 20 dr., which was followed by sharp lancinating pain in forehead for several m.; and after lying awake for an hours that n. slept well. 2nd. – At 10 and 12 took 20 dr., and at 2:30 my left ear commenced burning severely; became very red and swollen, and before bedtime a pimple began to form on the inside; slept well during n. 3rd. – Bowels constipated. 9, took 40 dr.; no new symptoms. 12, took 50 dr.; 3, took 60 dr. Burning in left ear increased. 5, took 70 dr., and at 9 took 100 dr. For 8 day, to 12th, I had a discharge of pus from my ears (l. more than r.) with severe burning and redness of the external (l.) ear. When walking, there was a feeling as if something was dropping inside the ear at every step. During the greater part of the time that I was taking the drug I could not lay the left side of my head on the pillow, on account of the soreness. (For several years during the winter I had been annoyed with a burning itching eruption on the lower extremity, always commencing as soon as I would undress. After taking the Juglans regia I was relieved of that trouble.) (H. L.SOOK, M. day, Ohio Medorrhinum and Surg. Rep., iv, 216.).
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.