22. August 25th, 6 a. m., took 1 gr. 2nd trit. C. – 26th, 6 a. m., 2 gr. – 27th, 6 a. m., 4 gr. Soon after taking it slight scraping in throat with warm feeling in back of mouth lasting 1/2 hour went off after drinking cold water. After 1 hour empty feeling in stomach, disagreeable sensation in intestinal canal with rumbling in belly for 1/2 hour – 28th, 6 a. m., 8 gr. Besides the scraping and warm feeling in throat, is obliged to swallow saliva; at same time, deep in oesophagus, an acute pain as if a small ball were pressed out on the left side. This lasted 1/2 hours and went off after drinking cold water. After 4 hours pain in left nape-muscles on nodding head. – 29th, 6 a. m., 16 gr. Scraping in throat; pain in nape went off gradually. After 5 hours tearing pains in finger-joints of right hand for several hour. Slight colicky pains in umbilical region, frequent rumbling and gurgling in bowels, but without stool. E., frequent discharge of fetid flatus. All day, frequent itching or, rather, biting like vermin on pubes and on glans. Some pain between left thigh and scrotum. – 30th, 6 a. m., 20 gr. The burning scraping soon after ingestion extended deep down the oesophagus, did not yield to cold water, but lasted over 2 hours. Colicky pains several times during forenoon. Stool at usual time. All day, biting itching in glans and scrotum frequently. The part of left thigh opposite scrotum shows a red, weeping spot secreting a fetid discharge; it pains like a sore when touched and also when walking, and then causes a gnawing. – 31st 6 a. m., 1/2 gr. 2nd trit. The burning scraping from the tongue down oesophagus that came on after the dose, spread, after 1 hour, over stomach and bowels, with frequent desire to swallow, which always caused the pain in oesophagus, like a ball being pressed through its wall. In forenoon, some stomachache, distension, and heavy feeling in abdomen, flatulence, and frequent, slight, colic pains. A liquid stool at usual time. All day, the biting in scrotum and the dark red, moist spot in thigh. – September 1st and 2nd. Each day, at usual time, liquid stool. Urine brown grew turbid soon, and deposited a copious brown sediment. The itching in scrotum and on moist, stinking spot on thigh as before; the spot is larger, but not so moist. – 3rd and 4th. Scrotum itches no longer, the eczema on thigh dry and covered with fine, white scales; it is less painful, but a similar itching occurs at anus, making him rub. – 5th, 6th, and 7th. No more smarting in eczema, only some pain when it is touched, redness diminished, no more scales. Itching of anus very troublesome, and it has recurred in scrotum. – 8th, 9th, 10th. Itching of anus, gone, the eczema of thigh is only a slight redness. – 11th, 12th, 13th. Well. (HENCKE, Archiv, xx 2, 183.)
23. a. Mr. N-, aet. 50, took several doses of C. 15. They caused some colic, nausea, dulness of head, and slight pain in forehead. Also itching on scrotum. A week afterwards he had a burning, itching eruption around neck, composed of small, hard, red, elevated spots, which went off in 4 or 5 days.
23 b. Another time he took 12 dr. of C. 4, which caused a feeling as if diarrhoea were coming on. For 7 days he took the same dilution, commencing with 5 dr. and taking an additional dr. every day. On 5th and 6th day, evening some colic and flatulent symptoms, with discharge of flatus. Four day after last dose several itching vesicles appeared on chin, which coalesced and became covered with a moist scab. Five days later the scab fell off and a red mark remained some time.
23 c. He then took C. 15 for 5 successive morning 1st day, 1 dr. After 5 morning rumbling in bowels. after 2 hours sinking in stomach and feeling of weariness. Empty eructation, slight tensive pain over right orbit, and pressure on right side occiput. In afternoon, discharge of flatus, with liquid stool and then urging till evening without evacuation. – 2nd day, 2 dr. After 4 hours sudden tearing pain in left upper arm, especially deltoid muscle, lasting 2 hours. Empty eructation, especially p. m., disagreeable feeling in abdomen as if diarrhoea would occur, hiccup, yawning, and peculiar feeling of anxiety, as if some misfortune would pen. – 3rd day, 4 dr. After 10 morning the rheumatic pain in left upper arm woke him, but it went off during day. Transient cramp-pain in right knee-joint; after 1/2 hours disagreeable empty and hungry feeling with rumbling in bowels; inside of prepuce slightly inflamed, with secretion. Cough from collection of mucus in trachea. – 4th day, 8 dr. M., liquid stool, empty erection. After dinner heartburn with nausea, tired feeling, eructation, flatus. -5th day, inflammation of prepuce gone, but instead itching in scrotum. – 6th day, 2 dr. C. 4. Pressure in pit of stomach, transient; headache as from deranged stomach, hunger without appetite, some vesicle in mouth and palate, wakes frequently. – 7th day, 4 dr. – 8th day, 8 dr. – 9th day, 16 dr. C. 4. Laryngeal catarrh. Throbbing in splenic region. Sinking and feeling of hunger, pressive pain in hypogastrium and bladder, itching in scrotum., pains on inner side of left upper arm, frequent sprained pain in left foot, diarrhoeic stool with urging. – 10th days, 32 dr. Pressive pain on the posterior end of left crista ilii, frequent cramp in left sole and inside of foot, itching on scrotum, copious stool with rumbling in belly, great discharge of flatus, evening-Four weeks later, 15 dr. Feeling as if diarrhoea would come on, sensation of insects creeping on face, itching on scrotum; evening, sinking and unnatural hunger, irritable, peevish, sad. Next day sad, anxious humour, great weariness, and emptiness. (Ibid. 186).
24. (External). CONWELL rubbed 15 dr. into arm of a girl of 15. This caused nausea, perspiration, and increase of urine. ( Froriep’s Notiz., vii, 13.)
25. C. Oil got accidentally into the eye. Though soon washed out, it caused violent pain, and in less than 1/2 hours inflammation of eye and face, roaring in ears and a kind of vertigo, he could not stand from fear of falling. After 4 weeks the eye was still weak. (COMMENSRY, four, de Pharmacie, xiii, 394.)
26. Four dr. of the oil rubbed around navel caused, in 1/2 hours, itching, then painful burning till evening. Next day erythema with pustules which formed scabs the day after. At same time painful febrile state and a herpetic eruption on scrotum. (LANDSBERG, ioc. cit.)
27. TAVERNIER poured 4 dr. on hand and rubbed this in around navel. After 2 hours the whole abdomen, without previous itching, was covered with innumerable small, lentil-shaped, elevated pustules, which were bright red and caused local irritation, but no itching. At night such violent itching came on he could not sleep and felt quite ill. Next morning the redness had declined, but the pustules were paler on their apices than on their circumstances. The skin where the eruption was tender to touch. The pustules gradually paled, but formed no scabs or scales. The 8th day, only some pale red spots were to be seen. ( Froriep’s Notiz., xii, 287).
28. a. C. M.-, medical student, November 12th, 10 p. m., rubbed the stopper of a bottle moistened with the oil twice over the left deltoid muscle. Slight redness of skin with cold feeling, then warmth. Sleep restless, full of dreams – 13th. Some itching on rubbed place. Neighbouring skin reddened even where oil had not come. many discrete, larger and smaller, lentil- shaped but yet pointed, dark red, little pustules. On moving arm, burning and itching. All forenoon, prostration of whole body and nausea; head confused. On touching and uncovering the rubbed place the pain, burning and itching increased. The whole place was elevated, nodulated, and rough to the feel; drowsiness, and prostration. Slight slumber, followed by chilliness over back. Confusion of sinciput. The small pustules disappeared after some day and changed to small, bright elevations of skin, the larger pustules remained for 5 days.
28 b. 14th. Rubbed 2 dr. on skin of left arm, below deltoid muscle. Slight redness of the whole part rubbed. The smell from the rubbed place caused giddiness in sinciput, and drawing pains through nose to its root and thence into brain; slight dimness of vision. Pressure in stomach with tickling sensation and slight spasmodic movement as though he should vomit. In external canthus of right eye twitching and shooting, with contraction and twitching of whole eye. Pressure in right side of forehead and temples. Heaviness, weakness, and loss of sight of eyes. Soon afterwards burning of rubbed place. Feeling and taste at tip of tongue like electricity and bitter-sweetish; great confusion of whole head, pressure towards forehead, and nausea. Cross humour; pressure in pit of stomach; slight chill; loathing and heaving to vomit. 2 p. m., pinching and griping in belly about navel and on left side of bowels; much urine. On the rubbed spot, besides the redness, the skin was rough. – 15th, morning, when lying on left side, throbbing, tension and frequent twitching in left upper arm, extending to fingers, so that he felt compelled to close th fingers involuntarily. A large number of large and small discrete, but thickly set red, pointed, and roundish pustules on the part rubbed and elsewhere. Touching, moving and rubbing caused itching and burning; heaviness of upper arm at shoulder. Skin slightly reddened, the pustules feel cough and elevated. The smaller ones declined into white, shining elevations of the skin. The whole place on the skin again became whitish, but the larger pustules remained for 5 days, when they gradually leaned, and only a few of them got whitish desquamation; as to the others, rubbing with the hand only brought out a few small scales. Both places on the skin of the left upper arm, which had been rubbed, gradually lost all the pustules, but itching remained for upwards of a fortnight, and also a feeling of weight and tension in the left upper arm. c. 19th, 8 p. m. rubbed 4 dr. on skin above navel. Warm feeling and slight burning of skin. Next morning pressure in stomach and full feeling the tightness of chest; heaviness and slight lameness of left upper arm. The pustules appeared just like those on left upper arm, but were broader, rounded, softer, and more elevated. They went off in precisely the same way. (BUCHNER, Archiv, xix, left 148)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.