The manifestation of drug action occuring in the extremities affected the muscles of the calves, especially the right calf. The effect was described as “cramps.” They began on April 13 following a misstep, to which mishap she attributed them. However, they continued until the experiment was terminated. The cramps always appeared from 6:00 to 12:00 p.m., while walking or standing, never at rest, and were ameliorated by rubbing the part.
Whether any conclusions can be drawn, based on these two rather incomplete provings of Sulfanilamide, as to the drugs therapeutic usefulness when prescribed according to the Law of Similars, can be determined only by further experiments of a similar nature. However, there has been shown, both in the 1940 proving and the present one, a definite relationship between Sulfanilamide and various types of skin lesions. Nothing very characteristic of the remedy seems to have been established unless it be “suddenness”: sudden vertigo, sudden onset of eruption, sudden onset of menses, sudden sore throat. In addition there appeared to be rather definite amelioration from open air and, in respect to itching , amelioration from hot bathing.
The schema appended is the same used in the 1940 proving with new symptoms added. As before, rubrics marked “T” indicate manifestations appearing in patients under treatment with crude sulfanilamide those marked “P” were developed in the provers. The numerals “40” and “42” are placed after “P” to distinguish between the symptoms of the earlier proving and the present one.
SCHEMA
MIND.
Dullness. T.
Confusion. T.
Loss of memory, accompanied by deafness. T.
Sensation similar to alcoholic intoxication. T.
SENSORIUM.
Vertigo. T.
Lightheadedness, as if drunk. T.
Lightheadedness, aggravated by smoking, ameliorated in the open air and when thinking of other things. P-40.
Faintness after breakfast, better by sitting bent forward, followed by vertigo and nausea. P-42.
Vertigo: Worse in the house, better in open air; accompanied by nausea; preceded by wave of heat from stomach to head with sensation as if head were whirling, and as if she would fall to left, better sitting bent forward; on entering warm room from open air. P-42.
INNER HEAD.
Headache. T.
Dull ache in the occiput with ringing in the ears, better in the open air. P-40.
Fullness and heaviness, as if cold would appear, worse in a.m. P- 40.
OUTER HEAD.
Pustules on forehead.P-40.
Soreness of the forehead.P-40.
Red, macular eruption right temple. P-42.
Pustular “whitehead” in hair above right ear. P-42.
Itching: of eruption on right temple; after scratching or
rubbing, burning; better by bathing in hot water. P-42.
Smarting and burning of pustule over right ear, better when discharging. P-42.
EYES.
Hard, red pimples with yellow tips on right eyebrow. P-40.
Red swelling on margin of left lower lid at inner angle. P-40.
Red swelling on margin of left lower lid at inner angle. P-40.
Stye at inner angle of left lower lid covered with several small yellow pimples. P-40.
Left sclera “very bloodshot.” P-40.
Sensation about left eye as from “little pin pricks,” especially on inner angle of lower left eyelid. P-40.
Swelling of both upper and lower left eyelids accompanying stye. P-40.
EARS.
Tinnitus. T.
Ringing in the ears accompanying dull ache in the occiput. P-40.
Stuffiness in the ears, relieved in the open air. P-40.
NOSE.
Scanty, watery discharge in the morning. P-40.
Yellow pimples on inside of left nostril. P-40.
Scabby sore on inside of left nostril which discharge bloody serum, worse when blowing nose. P-40.
Stinging over bridge of nose in the morning. P-40.
Red swelling on left side of bridge. P-40.
“Sore” on edge of left nostril covered with soft yellow scabs which discharges serum or blood. P-40.
Similar sore on edge of right nostril. P-40.
Pimples on the nose. P-40.
Pustule in the crease beside the left nostril, smarting, better when discharging. P-42.
Smarting and burning of “sore” on nose, worse from touch; better from heat and when discharging. P-40.
Sneezing. T.
FACE.
Pustules on the forehead. P-40.
Soreness of the forehead. P-40.
Papule over left zygoma surrounded by three others on an inflamed base, sore, aggravation from touch. P-42.
Burning-smarting papule in front of left ear becoming pustular, worse from touch, better when discharging. P-42.
Pimples on cheek near left nostril. P-40.
Skin-colored papules on left cheek on red base, stinging, accompanied by pressing-outward sensation. P-42.
Red pimple behind angle of left jaw, soreness, appeared during menses and after taking cold. P-40.
Sore, red pimple on chin. P-40.
“Blind boil” on chin, very sore, worse from touch, accompanied by pulling sensation. P-42.
Brown, pigmented spot behind angle of left jaw after pimple had healed. P-40.
MOUTH.
Peculiar taste in mouth as after inhaling hydrogen sulphide. P-40.
Pricking sensation on the tongue, as if fine needles were touching it. P-40.
DESIRES, AVERSIONS.
Anorexia. T.
STOMACH.
Nausea and vomiting. T.
Indigestion. T.
Noisy, tasteless eructations, worse when talking. P-42.
ABDOMEN.
Colicky abdominal pains. T.
Colicky pains in lower abdomen the day before menses. P-42.
Aching low down in pelvic portion of abdomen, as if menses would appear. P-40.
Bearing down sensation in pelvis. P-40.
Sensation in lower abdomen as if menses had appeared. P-40.
Full feeling in abdomen, worse after eating. P-42.
Full feeling in abdomen, worse after eating lunch. P-42.
Sudden emission of odorless flatus, worse from any change of position. P.42.
Itching, macular eruption just above the navel. P. 42.
Hepatitis and jaundice. T.
STOOL and ANUS.
Diarrhoea. T.
Constipation. T.
Eruption about anus, smarting and burning. P-42.
Moist eruption about anus, very sore. P-42.
Itching “sores” about anus. P-42.
Smarting and burning about anus worse from exertion, better from bathing in hot water, coating with vaseline. P-42.
Recurrence of old perianal irritation supposedly cured by Sulphur. P-42.
URINARY.
Slowing of and loss of force of urinary stream. T.
Micturition difficult. T.
FEMALE.
Menstrual flow less than usual. P-40.
Menstrual flow more profuse than usual. P-42.
Many small clots in menstrual flow. P-42.
Sudden onset of profuse menstrual flow.P-42.
Before menses: Aching in back and down legs to ankles; bearing down in the pelvis; aching in pelvic region; sensation in pelvis as if menses had appeared; aching in right leg. P-40.
Before menses: Colicky pain in lower abdomen the day before. P-42.
During menses: Red, sore pimple behind angle of left jaw. P-40.
During menses: Less pain than usual; flow more profuse than usual. P-42.
BREATHING.
Dyspnoea. T.
Persistent dyspnoea. T.
Hyperapnoea. T.
Asthma. T.
Cyanosis. T.
Pain in the chest. T.
HEART.
Tachycardia. T.
NECK AND BACK.
Red, macular, itching eruption on sides and front of neck, better bathing in hot water; after scratching, burning. P42.
Red, macular, itching eruption over left scapula, better from bathing in hot water; burning after scratching or rubbing. P-42. Smarting-burning papules between scapulae, worse from touch. P-42.
Aching in the back of the neck coming from the shoulder, worse when lying down. P-40.
Improvement of soreness of dorsal spine which had been present over a year. P-42.
Aching in the lower back before menses. P-40.
LIMBS.
Lameness in belly of right triceps, worse on beginning motion, better from continued motion and from rest. P-40.
Stiffness of right arm in the morning with lameness, aggravation from raising arm above head. P-40.
Aching in shoulder (right) proceeding up back of neck, worse when lying down. P-40.
Tingling and numbness of hands and feet. T.
Muscular weakness. T.
Aching from lower back down legs to ankles before menses. P-40.
Aching in right leg before menses. P-40.
Itching papules inner side right knee which form scabs after scratching. P-42.
Tiny, hard cores of epithelium exfoliate from surface of lower extremities. P-42.
Red papule on inner side of left knee having a pricking-out ward sensation, as if there was a piece of steel in it. It seemed to scratch the other leg when walking. Prover dug out a hard core which left a hole filled with serum. Took a long time to heal. P-42.
Cramps in calves of both legs, worse on right side, worse from 6 to 12 p.m., worse standing, worse walking, better from rubbing.P-42.
NERVES.
Paraesthesias. T.
Numbness and tingling of hands and feet. T.
General malaise and lassitude. T.
Easy fatigue. T.
TEMPERATURE and WEATHER.
Amelioration from hot applications. P-42.
Amelioration in open air. P-40.
FEVER.
Hyperpyrexia. T.
Hypopyrexia.T.
Sweating. T.
SKIN.
Urticaria. T.
Morbiliform eruptions. T.
Eruptions on exposure to sunlight. T.
Erythema multiform. T.
Jaundice. T.
Skin of lower extremities sensitive. T.
Sore, red pimples. P-40.
Sores with soft, yellow scabs, exuding bloody moisture. P-40.
Yellow pimples. P-40.
Scabby sore, burning and smarting, better from hot applications and when discharging. P-40.
Sore, red pimple behind angle of left jaw which appears during menses and after taking cold, and leaves a brown spot when healed. P-40.
Allan D. Sutherland was born in Northfield, Vermont in 1897, delivered by the local homeopathic physician. The son of a Canadian Episcopalian minister, his father had arrived there to lead the local parish five years earlier and met his mother, who was the daughter of the president of the University of Norwich. Four years after Allan’s birth, ministerial work lead the family first to North Carolina and then to Connecticut a few years afterward.
Starting in 1920, Sutherland began his premedical studies and a year later, he began his medical education at Hahnemann Medical School in Philadelphia.
Sutherland graduated in 1925 and went on to intern at both Children’s Homeopathic Hospital and St. Luke’s Homeopathic Hospital. He then was appointed the chief resident at Children’s. With the conclusion of his residency and 2 years of clinical experience under his belt, Sutherland opened his own practice in Philadelphia while retaining a position at Children’s in the Obstetrics and Gynecology Department.
In 1928, Sutherland decided to set up practice in Brattleboro.