Case II.-Mr. T–, aged 35, a travelling man, with Syphilitic history, came back from one of his western trips, with the following symptoms: Numbness in fingers and soles of feet, with much awkardness of all his motions. The staggering was marked and lie walked on a wide base. He could not distinguish between small objects with his fingers. His manual movements were irregular and would miss his purpose. His movements thus far were not more irregular by closing the eyes. His staggering was no worse when walking with his eyes closed. The reflexes, tendon patellae and ankle joint were abolished, and he had to wait a long time for his urine to start. Fulgurating pains coursed through his limbs and back and he was in a general way going down in bodily health. He says he has had these symptoms three months and they have grown stronger every day. His visual apparatus has been defective a long time but there are no new symptoms traceable to the probable nervous state. Every seven days he got one powder dry on the tongue- Alumina met. 200, no other medicine. A change for the better took place after the second dose. He took four doses in all. Every homoeopathist conversant with our literature must see a resemblance between this case and the one cured by Boenninghausen. While the symptoms in both cases are analogous to signs of sclerosis of posterior root-zones, yet, the essential features are wanting. But the action of the remedy, as applied for a purpose, is just as demonstrative. While it, in my judgment, is evident there was no sclerosis, it is highly probable that a disturbing factor was at work in the tracks of co-ordination, the posterior lateral columns; and in time a grave pathological change would have been established.