In assessing the possible value of homoeopathy in any chronic condition, a knowledge of the pathological state is, of course, required, but this in itself may not enable an accurate prognosis to be made, for instance, vitamin resistant rickets can respond to homoeopathic treatment. That there is a constitutional factor in rickets is apparent because when rickets was common, one child in an institution might develop the disease and others in the same environment and having the same diet did not. Without change of diet or extra vitamin D many of us have seen children suffering from rickets lose their night-sweats and improve remarkably after a high potency of Calcarea carb., Phosphorus, Medorrhinum, or other indicated remedy. The very fact that vitamin-resistant rickets exists is evidence that there is some other factor than the generally accepted pathology. On the other hand, idiopathic epilepsy does not as a rule seem to be influenced by Homoeopathy, although there may be no obvious pathological changes. To take another example bronchiectasis is incurable, but constitutional treatment can raise resistance to infection to such an extent that the patient’s outlook is appreciable improved something of obvious value when the disease is widespread. Such a child who had lobectomy performed, but was too ill for further surgery, used to get pneumonia with every cold. Constitutional treatment (with Bacillinum mainly was followed by a gain in weight of a stone in eighteen months and colds could be easily thrown off. We may fail in such cases, but Homoeopathy has something of potential therapeutic value whenever raising of resistance is a problem.