The effects of a hot infusion of roasted coffee having been observed, a fluid extract should be used as the basis of the pharmaceutical preparations.
Generalities
Increase of solid constituents of blood; of fat in serum and of fibrin in blood. Haemorrhages from nose, lungs, uterus and rectum. She walks uneasily up and down the room, with an anxious expression. Trembling; and muscular shiverings. Jerking (secondary effect). Reflex contractions in nearly every part alternately. Painful cramps in thighs, legs, feet, walls of chest and muscles of hyoid region at night. Restless. Feels strong enough to do anything. Weak. Peculiar sensation, somewhat like faintness. Aversion to open air, which aggravates symptoms (secondary effect). Left side generally affected. Amelioration from moderate outdoor exercise.
Mind
Delirium tremens; (after a rheumatic attack, with great weakness). Excitement; agreeable, with sweat; agreeable, causing wakefulness. Loquacity. Fear. Timidity and fear of sudden death, causing trembling. Anxiety. Love for family. Veneration for Supreme Being. Desire to perform good deeds intensified.
Imagination and memory stimulated. Power of judgment increased. Attention more alive. Impelled to push things, wants to keep going ahead and doing something. Brain clear and very active. Creative activity, vivacity of thought, versatility and ardor of desire, more favorable to the exaggerated expression of ideas previously formed than to the quiet examination of new conceptions. Mental energy taken away by sudden symptoms. Sensorium not clear, and next day obscure recollection of what had occurred, plain or connected answers were not obtainable, it was difficult to engage her attention, she repeated incessantly the same phrases in the most dolorous tone. Some what unconscious.
Head
Aching; (<) noon and evening; twice a week, usually lasting two days, commencing with neck beginning to grow stiff always on l. side, spreading over l. side of head and down over outside of humerus, across biceps, diagonally to elbow, (>) quiet, rubbing with ice or cold compresses and transiently by lying down, (<) jar in the moving, with tight feeling in head and pressure outward in occiput behind left ear, throbbing up and down in l. occipital region, when headache is severe l. side of breast is red and mottled in fine points, white and red, skin on l. side red-hot, moist and swollen, irritable mood, intolerance of noise, must have perfect rest, after the headache weak feeling in head and inability for mental labor. Rush of blood. Vertigo, (<) thinking, partially (>) change of position, with burning in stomach and faint feeling (secondary effects). Sensation as if everything in head were going in slow circles, now in one direction, now in another, with noises in ears.
Neuralgia in supraorbital nerve, extending through eye into malar-bone, first r., then extending to l., (<) r., (>) mental distraction and by sleep, pain at first dull, becoming sharp. Heaviness over eyes (secondary effect). Sensation as if a piece of lead were nailed to parietal bones, (<) motion of head. Stinging in locality of amativeness on l. side. Numbness in occiput, with aching and throbbing.
Eyes
Surrounded by blue rings. Conjunctiva of lids slightly red, (<) towards margin, and C. of bulb slightly red in canthi and corners. Pupils enlarged; but sensitive. Sensation of a fog. Intolerance of candle-light, it seems surrounded by a dim broad halo, causing pressure in brows. Muscae volitantes. Aggravation of myopia.
Ears
Every step and every loud word is painfully felt in ears. Ringing. Sounds of pounding or ringing in the distance. Roaring, buzzing and singing. Incessant noises.
Face
Pale; and anxious; waxy. Puffy, as if dropsical, waxy, pale yellow. Flushed. Lips and tongue pale and dry.
Mouth and Throat
Pain in r. lower teeth (sound), driving him nearly crazy, (>) cold water in mouth, returning as soon as the water became warm. Tongue dry. Spasmodic contraction of throat.
Stomach
Loss of appetite. Aversion to food, she can take only small quantities of water. Nausea, with faintness; N., with ineffectual retching. Vomiting with difficulty. Fulness in epigastrium and partial loss of appetite (secondary effects). Tympanitic distention of epigastric region, very sensitive to touch, less so to pressure. Cramp, with nausea. Anxiety in epigastrium. Tension so that she must loosen her clothes. Distress in epigastrium and l. chest, (<) cold water and cold food (secondary effect). Heaviness in cardiac region (secondary effect). Sinking and emptiness.
Abdomen
Painful tympanitic distention. Swollen and hard, (<) region of bladder, which was sensitive to touch. Rumbling; causing warmth, painful, forcing her to bend up and press with hands. Sticking. Warmth and coldness moving about alternately. Pain in hypochondria; just below spleen. Hepatic region sensitive. Ebullition in hypochondria.
Anus and Stool
Haemorrhoids. Discharge of bright blood every morning with the regular stool. Pruritus ani. Frequent diarrhoea. Copious stools, later constipation. Frequent stools; with tenesmus. Stool omitted.
Urinary Organs
Ineffectual urging. Micturition frequent copious, sp. gr. 1014; frequent, of scanty pale urine. Ischuria, with burning and pressure in region of bladder. Milky discharge (probably prostatic) at close of micturition, with smarting or burning at orifice of urethra, then cutting in sphincter vesicae or region of prostate (secondary effect). Tickling in urethra. Urine increased and colorless; increased, with diminished sp.gr., U. increased, but urea, phosphoric acid and sodium chloride diminished; and urea and phosphoric acid diminished, sodium chloride increased. Solid constituents of urine, except earthy phosphates, diminished. Urea diminished, it was not a diuretic though there was frequent micturition.
Genital Organs
Power lost: weakened in men. Spasmodic sensation deep in uterine region, it seemed as if something tried to press outward and could not because it caused spasms. Menstruation increased and prolonged. Pruritus vulvae.
Respiration
Asthma, with oppression of chest. Dyspnoea, with quick breathing. Rattling. Painful, short, rapid. Complained of want of air, and compression of chest and clung convulsively to the furniture or persons, but sank down powerless. Diminution of expired water; of expired carbonic acid.
Chest
Constriction.
Heart
Praecordial symptoms. Increased, vigor of action. Palpitation; and the impulse seems almost to raise chest. Diminished action. Fluttering.
Pulse
Rapid; and tense; and full; and together with heart losing one beat to every four. Slow. Variable, often almost imperceptible, sometimes intermittent (secondary effect). Decreases according to the tracings, with diminished extent of oscillation and consequent increase of arterial tension, but when the tracings are taken a few moments after an infusion of black coffee, especially when well roasted and of a strong aromatic odor, the peculiarities are directly the opposite.
Extremities
Trembling; of arms and legs. Chorea like movements; (<) hands. Gait tottering.
Skin
Itching.
Sleep
Restless on account of unpleasant and confused dreams. On going to sleep starting up in fright, with groans and fear of falling or of impending danger (secondary effect). Sleeplessness; from rush of all kinds of thoughts; with ecstatic excitement, intermittent, with dreams, Vivid dreams of magnificence. Dreams that the sky is spanned with rainbows from horizon to zenith, visions of enchantment, beautiful landscapes, view of Paradise, later dreams of the death of friends, which do not abate the exhilaration, but he looks at all with supernatural indifference.
Fever
Cold feeling. Shaking chills ascending from fingers and toes to nape and thence to vertex, with general shaking and chattering of teeth. Cayenne pepper taken internally produces warmth and makes him fearless (secondary effect). Shivering (on account of easy sweat) from least exposure to cold air (secondary effect). Shivering in lumbar region. Cold forehead; C. skin and limbs; feet and hands (secondary effect). Orgasm of blood. Heat; in flushes alternating with cold currents down back; in cheeks, with hot flushes in face, with scarcely noticeable redness. Sweat cool; cold, clammy, (<) palms (secondary effect).