Some Homeopathic medicines with their Grand characteristic symptoms which are useful for clinical point of view have been presented by John.H.Clarke in his book Grand characteristics of Materia Medica….


Aceticum acidum.

Cancer, diabetes, sickness in.

Phthisis, diarrhoea in.


Pallor on rising.

Expression of patient fearful anxiety: “Shall I never get better?” [Heart and brain affections]

All-pervading fearfulness. Avoids excitement; many people- Exaggerated cautiousness.

Fearful of death, predicts the day he will diet.

All bad effects of fright.

All acute inflammations with restlessness, hot, dry skin.

Cannot bear the pain, not to be touched, nor to be covered; (sometimes cannot bear to be uncovered).

Pains insupportable with great fear and restlessness.

Pains neuralgic, gouty, rheumatic, inflammatory.

Thirst unquenchable with great restlessness.

Stout plethoric people, active haemorrhage in such Vertigo, faintness, pallor on sitting up.

Pain intolerable. Loss of affection for anyone.


Movement of wind in descending colon (diarrhoea).

Noise as of explosion in heap and ears.

Ammonium muriaticum.

Throbbing in tonsils.

Anacardium orientale.

amel Entirely whilst eating

Agg After eating.

Antimonium tartaricum

Relaxation of all muscles and sphincters, with or without vomiting.


Constrictive sensation in abdomen and chest: dares not move or strain at stool for fear something would give way.

Arum triphyllum.

Boring fingers into nose.

Baryta carbonica.

Hand trembles in company of strangers.

Agg In damp weather.


Every cough causes pain in the womb (or hypogastrium)

Clutching pains (like Lyc).

Pains come and go suddenly, however long they remain.

In all internal viscera bearing-down pains (Sepia, Lilium tigrinum, Calcarea, Nx.m.).

III-effects of hair-cutting.

Takes cold with every draught of air, especially when uncovering the head.

Most inflammations and pains come and go suddenly.

After effects of anaesthetic vapours.


Serous effusions.

Coarse feeders; Swinish; Gourmands (Epicures, Nux).

Agg Movement, any degree or amount of; the more the movement, the Agg the pain.

Agg Heat of bed. At night (cf. Mercurius, Sul.) amel Quiet of body or mind. Amel Lying on painful side (Bel. Agg).

Inflammatory and typhoid fevers.

Lips dry and cracked.

Everything tastes bitter.

Pressure at pit of stomach as if a stone wEre in it.

Goes off with eructations.

(Gastro-enteric and serous affections.)

Calcarea carbonica

Hands warm, soft, moist; or cold, Clammy, soft and moist. Soft, boneless hands.

Agg After bathing or medding with water (cf. Sul.).

Agg AFter midnight (sweat, cough-:-cough Amel putting shoulders back-iod. Agg). Agg Morning.

Agg Ascending.

Agg By heat or light of sun. (Headache: of. Aco., Glo., Na.c)

Feeling as if had on damp stocking; cannot get feet warm.

Stockings actually are damp.

Cheerful in evenings.

Much perspiration accompanies most complaints but does not Amel (Cf Mercurius

Calcarea phosphorica.

School headaches.(Cf. Nat.m.)


Burning pains Amel by heat.

Carbo animalis

Knife thrusts in liver region, especially from right to left. (cf.Lycopodium)


No remedy has aggravation of anal symptoms so prominently.

(Guernsey. of., Sepia, Sul., Nux., Arsenicum, Mercurius, Nit ac., Graphites)

Stools pass more easily when standing.

Dark hair, rigid fibre.

Children totter and fall when walking.


Yawning constant in daytime, never sleepy.

First in all abdominal complaints

Windy colic in women.


Agg by eructations of wind. (pains in stomach and abdomen).


Pain (bruised aching) at inferior angle of right scapula)

Hours of aggravation generally four and five a.m.


Agg By slightest touch.

Amel By hard pressure, (Cf. Ignatia -Sul. has from Amel gentle pressure).

Terrible irritability.

Debility from;los of fluids.

Periodicity (of, Chi-sul., Arsenicum)

John Henry Clarke
John Henry Clarke MD (1853 – November 24, 1931 was a prominent English classical homeopath. Dr. Clarke was a busy practitioner. As a physician he not only had his own clinic in Piccadilly, London, but he also was a consultant at the London Homeopathic Hospital and researched into new remedies — nosodes. For many years, he was the editor of The Homeopathic World. He wrote many books, his best known were Dictionary of Practical Materia Medica and Repertory of Materia Medica