Homeopathic remedy Apis Mellifica drug symptoms and indications from Condensed Materia Medica by Constantine Hering, published in 1877….

      Poison of the Honey bee. BRAUNS. 1835. Apium virus.


      Loss of consciousness.

Sopor interrupted by piercing shrieks.

Impaired memory. Absent-mindedness.

Awkwardness, lets everything fall from his hands.

Dulness of head; indifference.

Could not bring his thoughts to bear on anything.

Muttering delirium.

Sudden shrill screams Hydrocephalus, etc.

Busy, restless, changing kind of work.

Delusive idea that he must run or hop, that he cannot walk.

Great tearfulness, cannot help crying.

Dread of death.

Apathy, hardness of hearing; happy expression.

Mood: irritable; hard to please; nervous.

Violence amounting to frenzy.

Jealousy (in women) Manias, especially proceeding from sexual cause in women.


      Confused vertigo, worse sitting than when walking, extreme when lying and on closing the eyes; nausea and headache.

Inner Head

      Brain feels tired; as if “gone to sleep,” tingling.

Dull heavy, tensive headache over the eyes, with pain through the orbits.

Chronic headache, violent pain in forehead and temples, at times involving the eyes, attended by vertigo, nausea, and vomiting, must hold the head and eyes down.

Burning and throbbing in the head, worse by motion and stooping, temporarily better by pressing the head firmly with the hands; occasional sweat.

Aching in the occiput.

Violent drawing from the back of neck, extending behind the left ear, spreading over let half of head.

Neuralgic pain, like a bee-sting, in and about left temple.

Congestion to the head and face; fulness in the head.

Child lies in torpor; delirium, sudden shrieking cries, squinting, grinding teeth, boring head in pillow; one side twitching, the other paralyzed; head wet from sweating; urine scanty, milky; big toe turns up; nausea while lying; breath offensive; tongue sore. Acute hydrocephalus. After erysipelatous eruptions.

Pain in occiput, with occasional sharp shrieks. Hydrocephalus.

Chronic meningitis, with considerable cephalic disturbance and symptoms indicating threatening if not actual effusion of serum in to the cavity of the arachnoid.

Hydrocephaloid; stupor; eyes red, head hot, shrill shrieks; tongue dry, skin, dry, hands colds cold and blue; urine suppressed, abdomen tender; diarrhoea mucous, offensive, involuntary, containing flakes of pus.

Hydrocephalic enlargement of the head.

Outer Head

      Head feels swollen; integuments feel swollen and stiff.

Hair falls out in spots.

Puffiness of scalp, forehead and around the eyes.

Erysipelatous inflammation of scalp and face.

Boring (backward) the head in the pillow.

Fontanelle sunken. Cholera infantum.

Copious sweat of the head, of musk-like odor.


      Squinting; trembling of eyeball, worse at night.

Rolling the eyes.

Severe, darting, lancinating pains in the eyes.

Burning, stinging, shooting pains.

Conjunctiva injected, full of dark vessels; chemosis.

Cornea: thick, having dark, smoky spots; greyish, smoky, opaque.

Ulcers on cornea; cicatrices; staphyloma corneae. Conjunctivitis, photophobia, but cannot bear eyes covered.

Scalding tears, profuse; great sensitiveness to light.

Lids: dark red, everted, swollen, excoriation of edges; granulated; swollen and very sensitive; oedematous, with bag- like swelling under the eye; non-inflammatory oedema (like [Arsen].); feel stiff.


      Hardness of hearing.

Redness and swelling of both ears.

Raises the hand to the back of the ears with each scream.


      Thick, white, fetid, mucous discharge, mixed with blood.

Nose swollen, red and oedematous.

Boils in nostrils, better from cold.


      Expression: happy, pleasant; of terror; apathetic; features distorted, face dark and much swollen; sunken, pale, sickly.

Face : pale; sallow; dark red; swollen, red and hot, with burning and piercing, more right side; oedematous, waxy, pale.

Burning cheeks, with cold feet.

Erysipelas of the face.

Stinging pain in left malar bone.

Lower Face

      Lips oedematous.

Raging, violent pains in the lips, extending to gums and head, finally to the whole body.

Roughness and tension in lips, especially upper.

Upper lip swollen, hot and red.

Lower lip chapped.

Burning : in the lips; on the chin.

Bluish lips from asphyxia; constriction of the throat.


      Jumping pain in left upper molars.

Sudden involuntary biting the teeth together.

Gums bleed easily.

Violent pain in gums.

Swelling and redness of gums and cheek, with sore pain and stinging in the teeth.

Dentition: gums sacculated, look watery, child awakens with screams; red spots here and there on the skin.

Tongue etc.

      Bitter taste.

Inability to talk, or put the tongue out.

Dryness of tongue; fiery redness of buccal cavity, with painful tenderness.

Rawness, burning and painful stinging blisters along the edge of the tongue.

Tongue: red at the tip: swollen, looks dry, glossy; cracked, sore, ulcerated, or covered with vesicles; coated white; glossitis.


      Dryness of mouth and fauces.

Scalding in the mouth and throat.

Fetid breath.

Viscid, tough, frothy saliva.


      Tonsils swollen, bright red, stinging when swallowing.

Deep ulcers on tonsils or palate; erysipelatous and oedematous appearance around ulcers.

OEdema of the glottis.

Mucous membrane covered with dirty, greyish deposit.

Tenacious mucus in the throat.

Throat swollen, inside and outside; hoarse; breathing and swallowing difficult.

Small blisters filled with clear lymph, in clusters, on back part of throat.

Desires Aversions

      No appetite, nor desire for food. Insatiable thirst; drinks often but little at a time.

In catarrh of chest, diarrhoea, diphtheria and some dropsies.

Thirstless. In cerebro spinal meningitis, ovarian dropsy, ascites and pregnancy.

No thirst with the heat; mouth dry.

Craves milk, which relieves.

Appetite for sour things.

Child nurses by day, refuses at night. After vaccination.

Eating and Drinking

      Continued swallowing relieves soreness and cough.

Vomits the food as soon as taken, followed by retching.

After eating: heaviness at stomach; diarrhoeic discharge renewed.

Nausea and Vomiting

      Bitter or acrid belching; heart-burn up into throat; water brash.

Nausea with inclination to vomit Vomiting: of bile; of mucus, with red specks; of ingesta and slime; and diarrhoea.


      Burning heat in stomach.

Pit of stomach sensitive; burning as from acidity; irritability of stomach; fulness; pressure aggravates the


Great soreness in the pit of stomach when touched.


      Violent burning pain under short ribs on both sides.

Sensation of soreness under the ribs.

Obliged to bend forward from a painful contractive feeling in the hypochondria.

Pain in hypochondriac regions, extending upwards.


      Fulness and enlargement of abdomen.

Rumbling in abdomen.

Sickly feeling in abdomen, inclines him to sit quiet.

Violent cutting pains in the abdomen.

Soreness of the bowels and abdominal walls felt when pressing upon them, or sneezing.

Feeling as if intestines were bruised. Dysentery Ascites.

Aching, pressive pain in the hypogastrium, with bearing down in the uterus.

Burning, stinging in the bowels.

Peritonitis, with exudation; often with metritis; urine scanty, dark.

Walls of abdomen tense; sensitiveness of ileo-coecal region. Typhus.

Stool etc.

      Throbbing in the rectum, with sensation in the anus as if stuffed full; tenesmus.

Diarrhoea; watery; yellow, with griping; watery and foul smelling; watery, copious, black; greenish yellow, mucous, worse morning; slimy mucus and blood. painless; olive green, slimy, profuse, full of bright red lumps; thin, yellow with extreme weakness, stool with every motion of body, as if anus were constantly open.

Costive, with large, hard. difficult stool; stinging pains, and sensation in abdomen as from something tight, which would break if much effort were used.

Hemorrhage from bowels, with burning pains, excoriation of anus, constant tenesmus. Prolapsus ani.


      Renal pains, soreness on pressure or when stooping.

Frequent sudden attacks of pain along the ureters.

Great irritation of neck at bladder, with frequent and burning urination.

Frequent desire, with passage of only a few drops.

Strangury, stricture, retained urine or inflammed bladder after abuse of cantharides.

Difficult urination, with children.

Incontinence, with great irritation of the parts.

Urine: scanty, high colored; red, bloody hot and scanty; scanty, fetid; scanty, reddish-brown; after standing, turbid; scanty, milky, albuminous; dark, with sediment like coffee- grounds; containing uriniferous tubules and epithelium.

Male Sexual Organs

      Frequent and long-lasting erections.

Swelling of testicles, more the right; violent itching and redness of scrotum, sore to touch.

Dropsy of the scrotum; hydrocele.

Female Sexual Organs

      Sharp, cutting, lancinating pains in ovarian region, extending down thigh; worse right side; numbness in side and limb.

Ovaritis Ovarian tumor.

Feeling of weight, heaviness in ovarian region.

Right ovary enlarged, pain in left pectoral region, cough.

Dropsy of the ovaries (right), or of the uterus.

Great tenderness over the uterine region, with bearing down pain; leucorrhoea and painful urination.

Heat and fulness of uterine region.

Burning or stinging pains in region of uterus of ovaries Menorrhagia, with heaviness in the abdomen, faintness, uneasiness, restlessness, yawning; may have red spots on body, stinging like bee-stings.

Suppressed menses, with congested or inflamed ovaries.


Dysmenorrhoea, with scanty discharge of slimy blood.

OEdema of the labia.

Ovarian tumors.

Leucorrhoea: profuse, acrid, green.


      Abortion during the early months.

Mammae: burning, stinging, swelling, hardness and suppuration.

Erysipelas of mammae.

Stinging, burning in scirrhus tumors of the mammae, or in open cancer.

Menorrhagia accompanying pelvic peritonitis.

Ulceration of the navel in the newborn.


      Hoarseness. morning, dryness, burning of larynx.

Speaking is painful; feels as if it wearied the pharynx in which there is drawing pain.

Weak feeling in larynx.

OEdema glottidis.


      Breathing: hurried and difficult, with fever and headache: short, quick; difficult, worse bending forwards or backwards; worse lying on the left side.

Great feeling of suffocation; cannot bear anything about the throat.

Oppression, worse ascending; worse in a warm room.


      Irritation to cough in the suprasternal fossa.

Severe cough, especially after lying and sleeping Cough: croupy, with ringing sound; dry, with gagging: with soreness of upper part of chest; with painful concussion of head.

Expectoration: seldom; sweetish or tasteless.


      Sensation of soreness, as if bruised or beaten.

Dull, aching pain in left side of chest, near the middle of sternum, with sensation of fullness in the chest and short breath.

Hydrothorax. after pleurisy.

Stitches in left side of chest.

Burning, stinging pains throughout entire front of chest.

Heart Pulse

      Sudden attack of acute pain just below the heart, soon extending diagonally toward the right chest.

Blowing sound with the diastole.

Pulse: accelerated, full and strong; feeble, scarcely perceptible at wrist; at times intermittent and imperceptible; wiry and frequent: hard, small and quick.

Outer Chest

      Chest feels as if beaten or bruised.

Neck Back

      Stiffness in the back of neck.

Rheumatic stitches in right side of neck.

Tensive pain from left shoulder to back of neck.

Burning and heat like”prickly heat.” on the back.

Lower posterior dorsal region, especially left, feels as if bruised.

Burning, pressing in coccygeal region, worse from any attempt to sit down; evening.

Upper Limbs

      Violent rheumatism in right latter in left shoulder.

Lame feeling in the scapulae.

Pressure under the scapulae, painful when moving.

Drawing pains in the arms.

OEdema of the hands.

Sensation of numbness in fingers, especially the tips about the roots of the nails.

Panaritium, with burning, stinging and throbbing; very sensitive to touch; especially in “runaround,” after abuse of Sulphur.

Lower Limbs

      Sore pain about left hip-joint; later, weakness unsteadiness, trembling in the joint.

Violent pain in left knee, more outside and to the front.

Sensation in the toes, with redness; feet cold.

swollen and stiff; also at night on removing the boots.

Burning in the toes, with redness; feet cold.

legs and feet waxy, pale, swollen, oedematous.

Limbs in General

      Trembling of hands and feet.

Limbs numb; cold.

Position etc.

      Inclined to sit quiet: Lying: on left side Sitting Rising: Motion Walking: Holds head and eyes down: Stooping: Bending forwards or backwards: Better by changing position of painful parts, which were worse by lying down.

Pains are better while moving or walking.


      Trembling; nervous restlessness.

Tired, as if bruised in every limb and especially in the back, like after exertion; worse on rising after sitting.

Great prostration.

Left side motionless; now and then moves the right arm : convulsions. trembling and jerking of the limbs.



Great inclination to sleep, but cannot, from nervous restlessness.

Continuous deep sleep.

Restless sleep and incessant dreaming.

Screams during sleep; also sudden starting.

Dreams: of journeying; of flying; of assembled people: unpleasant.


      Morning: 3 P.M.: Evening: Night: Day.

Temperature and Weather

      Closed rooms, especially if overheated, are insupportable.

Inclination for open air.

Cold weather aggravates weakness and chest troubles.

Worse getting wet through, but better from washing or moistening the part in cold water.

Chill Fever Sweat

      Chill about 3 p.m. worse in warmth: runs down the back, with great prostration Chilliness from the slightest motion, with heat of face and hands: towards evening.

Sensation of coldness without coldness of the skin: ague.

Skin burning hot all over, or gradually grows cool in some places, hot in others.

Heat, with inclination to uncover.

Dry, hot skin, or alternate dry and moist skin.

Sweat after trembling and fainting, then nettle-rash.

During hot stage more or less violent headache, generally a continuous deep sleep. Intermittent.

Sweating stage either absent or of a very light grade. Intermittent.

Continuous low fever; no thirst; worse 3 p.m. is then very drowsy.

Typhoid forms of fever, especially enteric, cerebral, exanthematic forms; febris nervosa putrida.

Thirst wanting during sweat; may or may not be present during heat, always thirst during the chill.

Apyrexia: pain under short ribs left side; feet swollen; urine scanty; limbs and joints sore; restless; urticaria.


      Pains return periodically in diphtheria.

Sudden sharp paroxysms of pain.

Pains suddenly migrating from one part to another.


      Right : Left: Left to right :Right to left: Below upwards: Above downwards:.


      Burning, stinging like bee-stings, and soreness, seem to be the predominating painful sensations- while itching, tension and throbbing may be or may not be painful.

Numbness of external parts.


      Affections of circulatory apparatus and fluid, dropsies, phlebitis, varicose veins, ecchymosed spots gangrene, unhealthy suppuration. Periosteum inflamed.

Serous membranes: inflamed; effusions; synovitis.

Mucous membranes inflamed and catarrhal.

Glands enlarged, inflamed.

Muscles stiff, tender on pressure, somewhat swollen; rigid rheumatic inflammation.

Indurations: scirrhus, or open cancer.

Contact Injuries etc.

      Touch: Pressure: Cannot bear covering:.


      Stinging, burning, prickling, smarting, or itching of the skin; sensitiveness to the slightest touch.

Skin very hot and red.

Red spots on abdomen and other parts; burning, stinging.

Intensely deep red rash.


Measle-like eruption.

Small pustules, with burning, smarting, stinging; forming dry, scaly, laminated, brownish scabs.

Body covered with large, while wheals, deep scarlet interspaces.

Erysipelas, with bruised, sore pain and much swelling.

White miliary eruption on chest and abdomen.

Nettle-rash in warm weather, when one cannot sweat.

Skin: pale, waxy, almost transparent; dark blue, almost black.

Carbuncles, with burning, stinging pains.

Stages and States

      Strumous diathesis.

Bilious, nervous temperament; women and children; especially widows; girls, who though generally careful, become awkward, and let things fall while handling them.

Old people, asthma.

Those predisposed to miscarry should not receive [Apis] except in high potencies.


      Antidotes to massive doses and in poisoning: [Natr] [mur.,] the substance, the solution, the potencies; sweet oil, as it contains table salt; onions; bleeding is decidedly a bad palliative, and is in most cases injurious.

Antidotes to potencies: after overdosing, [Ipec], low, relieved much; to drink coffee, seems indifferent; some have given [Apis], high, Laches, and Lact ac.

(Has been given in ailments from stings, and from anthrax infection).

It is an antidote to Canthar. (Ischuria, inflammation of bladder, acute Bright’s disease); abuse of [Iodium], [Cinchon], Digit.

It follows well after vaccination (erysipelas, painless diarrhoea); after [Sulphur], in panaritium.

After it follows well: Graphit. (tetter on ear-lobe); [Arsen]. (hydrothorax); [phosphor]. (absorption of the false membrane in diphtheria): [Stramon]. After [Apis] has removed the jealousy in mania; [Lycop]. (in staphyloma); [Sulphur] (in hydrothorax, pleuritic effusion, hydrocephalus); [Iodium] (in puffy, swollen knee).

Complementary: Natr. mur.

Has been given in alternation in cases when the change of symptoms indicated it with: [Iodium] in swelling of knee; [Sulphur] in swollen eyes: Hepar in urticaria; [Mercur]. in ascites with peritonitis; [Lycop]. in staphyloma.

It often disagrees after Rhus tox. in eruptive diseases; and Rhus tox. given after [Apis] has often disagreed.

Collateral relation (belonging to the same family); Bombus, Crabro. Vespa.

It has cured where [Bellad]. failed in cough of horses; where [Bryon].,[Canthar].,[Digit]., [Helleb]., etc., had failed in albuminuria after scarlatina; cases in which Pulsat., seemingly indicated, failed, especially in uterine complaints; when [Thuja]. [Phosphor]., [Canthar]., etc., had failed in affections of the prostate gland.

Concordances: [Acet. ac].(dropsy); [Acon]., [Anac].(urticaria); [Apocyn]. [Cannab]. (dropsy): [Arnic]. (bruised sore); [Arsen]. (typhoid forms; gangrene: dropsies: scarlatina; urticaria; chills); [Bellad]. (meningitis, especially of cerebral meninges; faucitis; erysipelas; scarlatina; glandular organs, etc.); [Bromin] (swelling of ovary during menses); [Bryon], [Cantharides] (erysipelas, urinary symptoms); [Cinchon]., [Colchic]. (rheumatism, etc.); [Crot. tig]. (urticaria); [Euphr]. (conjunctiva); [Ferrum]; [Graphit]., [Hepar]; [Iodium] (swollen knee); [Laches]. typhoid states; gangrene); [Lycop]. [Mercur],; [Natr. ars]; [Natr. mur] (chills.; urticaria; tension in ovarian region, etc.); Pulsat.: [Rhus tox]. (eyes, but Apis has less suppuration; vesicular erysipelas, but darker than in [Apis], and spreading left to right; typhoid states; restlessness, but, in [Apis] more fidgetiness, etc.); [Rumex crisp]. (painless, greenish-yellow diarrhoea); [Sabin]. (ovarian and uterine symptoms); [Sepia]; [Silic]. (ovary and inverted nipple); [Sulphur] (tubercular meningitis; cheeked eruption, especially urticaria; asthma; hydrothorax); [Tereb]. (urinary symptoms); Therid. (vertigo); [Thuja] (sycosis, evils of vaccination); [Urt. ur]; [Zincum]; [Calcarea iod]. (which has relieved conical cornea and staphyloma); [Guarea] (has cured conjunctivitis with marked chemosis).

C. Hering
Hering got the degree of M. D. from the University of Wuezburg with highest honours. The theme of his thesis was "De'Medicina Futura" (The medicine of future). Hering left Germany for West Indies and finally arrived at Philadelphia in Jan, 1833. He established a homeopathic school at Allentown, Pennsylvania, commonly known as "Allentown Academy". Soon he became very popular as a physician. He is known as the 'Father of Homeopathy' in America.