Strychninum

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3. After the death of a dog poisoned with S. I examined spinal cord and brain, chiefly with a view to discover any congestion which might have existed in the several parts. In the brain I met with no unusual degree of congestion, but I was particularly struck by a remarkable condition of the grey matter of the lumbar bulb; it presented, in fact, numerous small effusions of blood, while in the medullary portion no abnormity was found. In another dog, similarly killed, I found in the grey matter of the lumbar portion aneurismal dilatations of the capillary vessels, which were in consequence on the verge of bursting. In both cases the two horns of grey matter were most beautifully injected with blood. (VAN DER KOLK, Spinal Cord, &c., New Syd. Soc., p. 78.)

4. ARNOLD (of Heidelberg) found that if gr. 1/2 is administered to a frog, tetanus comes on in not more than 5 m., and death ensues in 45 – 90 m. After gr. 1/10 it supervenes at about same time, but death comes later. After gr. 1/100 it took 10 – 20 m. to develop, but continued in one case for 48 hours, frog being found dead after 54 h. In young frogs, gr. 1/100000 brought it on in 7 – 12 m., and it lasted 7 h. On giving gr. 1/1000000, after 1/2 hours or so irritability was somewhat increased, but no spasm ensued in strong, full – grown animals. But in one frog, which the day before was tetanic for some hours after gr 1/10000, but which had quite recovered, a slight attack came on 1/2 hours after gr. 1/1000000, ending in the death of the animal after some hours (Hygea, xii, i, 56.).

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Richard Hughes
Dr. Richard Hughes (1836-1902) was born in London, England. He received the title of M.R.C.S. (Eng.), in 1857 and L.R.C.P. (Edin.) in 1860. The title of M.D. was conferred upon him by the American College a few years later.

Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.
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