29. Feb. 13, took 2 globs. of 8th dil. – 14th. Shooting pain in liver and kidney, pale face – 17th. Accumulation of flatulence. – 18th. Same dose. – 19th. Pain in gall – bladder, accumulation of flatulence, stretching with yawning, heaviness of bowels. – 20th – 24th. Very cold feet, frequent fever, much toothache, burning on palate. – 25th. Same dose. After 1/2 hours acute stitches in gall – bladder. – 26th – 28th. Very cold feet, much headache, especially towards evening and m., also n. Great prostration and laziness in all limbs. – Ist – 3rd March. As last report. – 4th. Smelt at same dil. – 4th – 10th. Very cold feet, coldness of all body. – 15th. Pain in throat, shooting in uvula, both sides rather red, very painful when swallowing, lasted all day and was very painful, with rigor and deposit of viscid mucus, which could not be detached – 17th. Coldness of all the body; icy cold, sweaty feet; icy coldness in stomach with borborygmus. – 18th. As yesterday, borborygmus when stretching out abdomen. Before a meal frequent belching with cold feeling in stomach, the bowels feel tied up. Frequent fits of pinching pain in liver. Gall – bladder shooting as before, which is relieved by discharge of wind up or down. After unusual stool, a. m., of bright- coloured feces in thin strips, looking almost like porridge, some drawing pain in right side, just above hip; then extending up to ribs and down towards kidney, going off after discharge of flatus – 24th. Got chilled in church, so that he could scarcely get warm again. After dinner violent toothache in right posterior upper molar. Thence the pain spreads to sinciput, and lastly enters head, cheeks and both rows of teeth on right side; it goes off at n. in bed. – 25th – 28th. Severe coryza, sore throat, chest feels raw, head or teeth ache, especially after eating. As a rule had seldom good appetite, often insipid taste, sometimes nausea. Had usually 3 or 4 hours of good sleep at n., then frequent waking and restless tossing about. (Ibid.).
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.