b. 27th, 7:30 a. m., 10 gr. 3rd trit. Before taking med. pressure in left ankle and right elbow, right thumb and index, and third metacarpal bones. Pressing in right femoral muscles and left elbow – joint. 8 a. m., pressure in joint of left middle finger. 9 a. m., pressing in left shoulder – joint and muscles above right knee. 1030 a. m., tearing on inner side of left upper arm. Pressive pain in joint of right big toe for 1/4 hours, hindering walking, returns at noon, lasts 1/2 hours, also pressure in nape extending to occiput, aggravated by moving neck. 1 p. m., persistent pressure in joint of left middle finger, later in joint of right index. 3 p. m., tearing in forehead. Sudden pressure in right shoulder for a few seconds, then in right wrist and left trochanter, in left nape – muscles extending to left ear, with stiffness and pain on moving head, repeated later. 5 p. m., pressure in left ankle when walking. 6 p. m., drawing in right toes, pressing in left wrist, shootings through left thumb, in back with pulsation. 7:30 p. m., burning like pepper on tip of tongue on tip of tongue; compression in lower part of left calf, in joint of right index. Occasional shooting in orifice of urethra; pressure in right scapula, gradually increasing and going over shoulder, afterwards in left knee – joint. – 28th., 8 a. m., pressure in joint of left middle finger and left nuchal muscles, later in right knee with tired pain. 9 a. m., pressure in left shoulder – joint, in joint of left big toe, later in right big toe. Sudden pressure in right shoulder, then in left, later in both knees. In evening of 27th occasional stitches in inner canthus of left eyeball, same on 28th. 4 p. m., pressure in left knee; drawing in joints of left fingers. – 29th, 6:30 a. m., on rising, boring pain in 2nd joint of left thumb, drawing in toes. 9 a. m., tearing on inner side of both upper arms, then in joint of left thumb and outer side of left leg. Boring in left temple. Pressure in right knee, in joint of left index. Drawing in upper right teeth. Tearing in right shoulder – joint and in forehead, 1 p. m./ Pain in left side of nape, at first burning, then with feeling of coldness under skin. 6:30 p. m., when urinating, cutting in orifice of urethra, boring in joint of right big toe and right shoulder – joint, pressing in right wrist, when above right elbow, in left wrist. Tearing in left scapula, at same time burning pain going into nape, increased by moving head; on right shoulder joint repeated pressure. 8 p. m., pressing above left wrist, extending into fingers; repeated pressure in and below left outer ankle. Painful burning on left side of nape muscles and stiffness for several h. Tearing in left foot. – 30th. Woke at 5 with shooting pain in joint of left big toe and on left side of nape. 7:30 a. m., same dose. 8:30 a. m., pressure in left pectoral muscles, in right forearm. Drawing in left thumb, in left little finger and along hand, in right shoulder – joint. Tearing in right toes, in forehead, in right elbow – joint, in bend of left elbow, in right hand. Pressure in left knee, in left wrist going into fingers, especially left thumb. Wandering pains in left thorax, especially under left nipple. Repeated drawing in flexor aspect of left forearm. Drawing in left side of nape with stiffness. Pressure in joints of left fingers; shooting pains in soft parts under left axilla extending backwards. Tearing in joints of left 4th finger, in knees, occiput, wrists, tibiae. Pressure and burning in left side of nape extending to occiput and clavicle, with stiffness; later coldness and pricking in skin, lasting 1 hours, and not quite gone till 1 p. m. Later, burning in tip of right big toe under nail for some m. – 31st, 9 a. m., boring in left ankle – joint, drawing in right knee down leg. 6 p. m., pressure on inner side of left knee. 7 p. m., tearing in sinciput; pressure in left inner ankle; tearing in right fingers and pain in left side of nape. 10 p. m., sudden pressure in right shoulder – joint, then in left scapula. – Sept. 1st, 6:30 a. m., 30 gr. 8:30 a. m., drawing in forehead and nape. Tearing above both ears and in shoulders. Crawling as of an insect on back of nose repeatedly. 9 a. m., pressure in right elbow – joint; drawing arms. When urinating, cutting in orifice of urethra, continuing after urination. Boring in left elbow. During day several of former pains; tearing in inner side of both upper arms. – 2nd, 6:15 a. m., on rising pressure in left thumb – joint and shooting in left shoulder – joint. 7 a. m., drawing in skin over right zygoma. Drawing in left side of nape. 3 p. m., tearing in left fingers and toes repeatedly. Burning in left side of tongue. Boring in joints of left third finger; repeated boring in right, then in left temple., Stitches under left ribs anteriorly. Occasional pain in right trochanter. Pressure on sides of dorsal vertebrae. Occasional pain in right trochanter. pressure on sides of dorsal vertebrae. Pin in left hip – joint on treading. Drawing in ankles when sitting and walking. 10 p. m., pressure between sternum and right nipple when sitting, increased by pressure and inspiration. Pressure in right knee, long continued when sitting, the boring in bone behind right ear and in frontal bone; pressure in right shoulder. – 3rd, 8 a. m., tearing on left side of hand and left shoulder. Stiffness in left side of nape; tearing in left knee down leg. Shooting under left ribs anteriorly, also at 3 a. m. During day much tearing in joints, left side of nape, right side of head, in right shoulder and elbow – joints repeatedly, on left scapula, in knees Pains worse e. Woke at 2 a. m., and felt tearing in toes and knees.
c. 4th, 7 a. m., 10 gr. 2nd trit. 8 a. m., pressing in left wrist; shooting pains in region of left nipple. Pressure round about left elbow, above and below it, in right big toe, at side of head, left side of nape. 1 p. m., stitches under left ribs anteriorly for 1/2 hours, increased by inspiration and pressure, when walking. All day frequent pains in joints named, in cranial bones, in nape. 11 p. m., on going to bed, shooting in tip of right then of left big toe, pressure in their joints, in the other toes, and in chest between nipples. – 5th. During day same pains in joints of hand, shooting in tips of toes. Burning as from pressure on tip of tongue; stitches under left ribs anteriorly. – 6th, m., in bed, pressure in right scapula. 7 a. m., same pain in left elbow – joint, for several m., and in scapulae. Drawing in right toes and sinciput, repeatedly. Pressure on inner side of both upper arms and on sides of dorsal vertebrae. During day pressure in joints, especially of knees, shoulders and fingers. Burning on tip of tongue; tearing on right zygoma and cranial bones. – 7th, 6:45 a. m., 20 gr. 8 a. m., pressure in finger joints, knees, ankles, elbows and big toe. Pain and stiffness in left side of nape; drawing in inner side of both upper arms; pressure in right side of forehead. Persistent pressure deep in right hip – joint. – 8th. Same pains in joints, dorsal muscles, knees, shoulder. – 10th, m., tearing in fingers, toes, right sole, repeatedly. Pressure in wrists and knees. Tearing in right side of head, forehead, ankles. Many pains in joints and tibiae, when walking and sitting. At n. on walking pressure in joints of big toe, burning in its tip and under nail. – 11th, 7 a. m., drawing in joints of right fingers and wrist. Pressure in right knee. Pressure behind left ear, on right zygoma, and in other joints. Stitches on right pectoral muscles, increased by inspiration. When walking a feeling deep in right leg as if the part were swollen or congested with blood, for 1/4 hours; this sensation occurs repeatedly. Wandering boring in bones of root of nose. Shooting on left trochanter, evening, increased by pressure, for 1/2 hours – 10th. Much sneezing. – 11th. Tickling in larynx and dry cough, also n. Pains as before. – 12th, m., pains in big toe and ankle, right shoulder – joint, then lo. During day the former pains. At same time frequent scraping in larynx and dry cough. – 13th. Same pains and cough.
Day 14th, 6:30 a. m., 10 gr. 1st trit. 8 a. m., drawing fingers, left side of nape, occiput, toes; pressure in joints of right big toe, 11 a. m., tearing in left zygoma and right forearm. Pains in joints as before, boring in tip of tongue. Many pains in joints of big toes and fingers; tearing in various parts of head. On lying down, evening, pain in left wrist, increased by moving it. On waking, m., pressure in toe – joints. – 15th, 8 a. m., pressure in shoulder – joints. 8:30 a. m., 20 gr. Tearing in different parts of head. Persistent pain in nape and stiffness; pressure in shoulder – joints. When walking, contraction like cramp in muscles of left calf. evening, tearing and pressure in right side of occiput. Some of these symptoms continued till 23rd.
Evening 24th, 7 a. m., 20 drops of a solution of 5 gr. of Nat. sul. in 1 oz. water. The accustomed pains in big toes repeatedly. Drawing in left cheek as if skin were drawn up. Drawing in right finger – joints and knees. 9 a. m., deep pressure in left side of lumbar vertebrae, increased by moving body and pressure. Tearing in front of right thigh. Boring in finger – tips. Pains in joints, tearing in forehead. evening, drawing in joints and behind left inner ankle; stitches in balls of big toes. 10 p. m., tearing in right side of crown and in right instep. Drawing deep in right hand to fingers and arm with some feeling of exhaustion and internal heat. Boring and shooting in tip of tongue, then former pain in left arm from shoulder, and in left ankle – joint. – 25th, 7 a. m., 4 dr. Immediately shooting in big toe. l; 8 a. m., drawing in left finger and wrist – joints, shoulders and dorsal muscles. 9 a. m., pressure in left little toe, and left side of nape; drawing in left side of lower jaw. 8 p. m., frequent pressure in shoulder, knee, elbow and ankle – joints; cutting in forepart of urethra when urinating. – 26th, 6 a. m., soft stool at unusual time; burning in tip of tongue, some joint pains. 2 p. m., took a teaspoonful of solution; pressure and tearing in joints as before. 6:30 p. m.,. when sitting anxious feeling in heart, rapid, short heart’s beats, with dimness of vision; wishes for open air, which relieves. 11 p. m., tearing in shoulder and wrists, and 2nd soft stool. He took till larger doses of this solution and afterwards 5 and 10 drops of 100th dil., but no fresh symptoms were developed, the same pains in joints, nape and head occurring with greater or less severity. (N. Zeit. f. hom. Klin., xi, 97, et. seq.).
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.