2. I prescribed for a woman suffering from uterine atony Helonin, 1st trit., 2 gr. 3 times a day. In a few day she came to me complaining of an entirely new and annoying symptoms viz. intense irritation of external labia and pudendum, which were puffed, not red, and burned and itched terribly. So intense was the irritation that she could not prevent herself from scratching with her nails until the surface bled. Every morning cutaneous surface would fall off in thin, transpiration exfoliations. Mucous membrane of labia was red, swollen, and covered with white crudy deposit like aphthae. Urination was very painful, on account of the scalding sensation as the urine passed over the denuded mucous membrane. No sexual excitement was present. Speculum showed inflammation to extend one third the length of vagina. On suspending Helonin, and prescribing lotion of borax, in a few day symptoms subsided. (E. M. HALE, Am. Obs., x, 55.)
3. Dr. E. CLARK has observed in 6 or 8 cases, from 1st trit. of Helonin, pain lower part of back through to uterus, piercing, drawing; breasts swollen, nipples painful and tender, will not bear pressure of even ordinary dress; great uterine haemorrhage came on, and continued till drug was left off. (IBID., New Remedies, 2nd ed.).
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.