29 b. 29th, 9 a. m., 40 dr. Liquid stools at 10 and 10:30 a. m. Repeated shooting in rectum at 12 an 4 p. m. Much scraping in larynx an dry cough. On same day coryza with much sneezing, cough, and expectoration of mucus, scraping in larynx, rough voice. – November 1st. Slight fever, some heat, and confused head. The cough, which was at first especially at night, violent and dry, with much tickling and scraping in larynx, was afterwards accompanied by white, yellow, and green expectoration. By the 12th it had nearly eased. The coryza lasted till the 20th. – 20th, 7 a. m., 40dr. Confusion and heat of sinciput at 7:30 a. m., lasting several hours. Soon after taking med. scraping in fauces all day. – December 19th, 7:30 a. m., 50 dr. Head confused; pressure in lumbar vertebrae, aggravated by bending and pressure, last all day with intimations. – 30th, 6:30 a. m., 60 dr. 7 a. m., sinciput confused and heat for 2 hours. No other symptoms. (LEMBKE, N. Z. f. h. Kl., iii, 65.).
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.