1 m. Anxious trembling through whole body; lack of desire to do anything; she feels least comfortable in morning; she feels better in open air than in room, her symptoms seeming almost entirely to disappear in open air; tingling now her now there all over body, often in rapid succession, going off by scratching; cracking of joints on movement, not without some pain; an old indurated bruise on finger immediately forms matter, and becomes painful and sore.
1 n. Cold thrill along back, over shoulders and down arms, with goose -skin and frequent yawning (5 morning); he feels chilly (1/2 hour); feeling of coldness in back (2.1/2 hours); at 9 p. m., 4 hours after taking drug, he feels chilly, as if (which he was not) in a room without a fire, which feeling gradually increases to a shaking chill all over body, with pale face and icy-cold hands; at 7 p. m., 8 hours after taking drug, sneezing, and then immediately rigor from back down to feet, scarcely in anterior part of body an face was warm, no subsequent heat; all p. m. chilliness with some thirst; yawning and chilliness after supper, with burning of eyelids and thirst for cold drinks, without drinking much; he is seized with great heat, so that he feels tingling in skin; distended veins with feeling of heat but only moderately increased temperature of skin; scarlet-redness of whole body; ebullition of blood, as if there were movement in whole body, without any perceptible heat; he had violent heat over whole body, but especially about head, with redness of face and violent thirst, without much dryness, for some hour (towards evening of 2nd day); a quickly passing suffusion of warmth (1/4 hours); heat in face without any great redness; uncommon feeling of heat and prickling in skin, as if sweat would break out, skin being itself father cool than hot; excessive desire for cool drinks p. m.; palpitation, anxiety about heart, whence a weak feeling passes down through whole body, as if it would collapse, and so down to feet (2nd days).
1 o. Uncommon mirth and cheerfulness; alternation each evening of spasms with extremely variable temper; during great debility with dilatation of pupils, strong inclination to jest and laugh (4 1/2 hours); very cheerful mood is witty, joking, loquacious; inclination to sing; even when out of humour, quick humming of a lively tune; if someone happens to sound a note she begins to sing involuntarily and then laughs at herself, soon, however, singing again in spite of determination not to do so; there suddenly comes before her fancy a concert at which she was present a long while ago, as vividly as if it were going on before her, so that she can distinguish the separate instruments; immoderate laughter as if he would die; disagreeable mood, vehement, out of humour, quarrelsome, an hour after loquacious, merry, laughing, and singing; frequent alternation of cheerful and sad humour; disagreeable feeling as if he were longing for something without knowing what, with a sort of anxiety, which, however,, leaves him very cheerful; is sometimes very angry with people, and next moment would like to embrace them; a slight thing which would make her laugh at another time now excites here almost to rage, so that she is near losing consciousness, afterwards she is astonished at her passion (4th days); reproaches make here very angry, she wants to justify herself, but the words vanish on her lips, – vexed at her silence she tries to speak again and again becomes dumb, continuing wavering in this fashion, and not succeeding in uttering a single word in her defense though she tries very hard;the manners of a relative whom she loves excite her range, she is on the point of breaking out when she feels calm again, next moment this calmness seems to her weakness, at which she is vexed, and she is more angry than ever, – and so on for several hour (in quite unwonted way) (2nd days); vacillating peevish mood, – a slight cause excites his anger, for which he is sorry the next moment, but it soon returns and he frets that his calmness hinders him from giving vent to his feelings, he exchanges a harsh word he was about to utter for a milder one and vice versa (after several day); uneasy, anxious, mood; melancholy sadness, hypochondria mood; he takes everything in bad part and then repents of having hurt other people’s feelings; if he attempted to write anything down he was unable or want of ideas; she feels for a few movements as if her thought would vanish; great forgetfulness, she inquires about a thing and next moment forgets what she had been inquiring about; during an interesting lecture he became suddenly and peculiarly sad, so that in spite of every effort he was unable to fix his mind upon the subject (10 hours); absence of mind and forgetfulness, even to non-recognition of friends; his mind errs, and he is mistaken about the time and about objects, although these are near and distinctly visible. (STAPF’S Beitrage.)
2. THORER. [Mode of obtaining symptoms not specified.] Confused sensation in forehead; headache on right side (3 hours); shooting headache with dry coryza; violent headache for 3 days, – quite unprecedented; violent burning of eyelids; violent stinging itching of left upper eyelid, compelling rubbing (1st evening); frequent darkness before her eyes (1st day); excessive hunger, the must eat every morning (1st day, p. m.); drawing, first in epigastrium then in uterine region; the child suddenly complains of colic, and bends double (2nd days); sacral pain, morning and night in bed, on movement; itching on right side of scrotum (1st and 2nd evening); hoarse voice with some cough (2nd morning); agitation of blood and palpitation; bruised feeling in both shoulders; sudden violent tearing pain in right elbow-joints, disappearing again immediately. ( Ibid.)
3. WAHLE. [As 2.] Her senses readily vanish, and all becomes dark before her eyes; whizzing as of a strong wind in head; humming and roaring in ears; Metrorrhagia from slightest movement; very frequent palpitation; great sense of emptiness in stomach; frequent faintness; the least thing puts her out of humour that she does not know what to do, with anxiety and trembling through whole body; indifferent to everything; joyless and sad, alternating with mirthfulness; the least thing that affects her drive her thoughts quite away. ( Ibid)
4. VEZOLD observed “inflatio colli” in a girl of 18, who had swallowed 3j. riverius states that it may cause even fatal hemorrhage from the uterus, especially after delivery. Tralles relates that a women from odour while putting it up in paper in a heated room became over come and lay for a time as if apoplectic. Zacutus Lusitanus speaks of having seen from it excessive gaiety, bordering on delirium, with pallor, headache, obscuration of vision. Boerhaave speaks of almost constant unbecoming laughter as an effect of it; and Schultze says that children laugh as soon as they smell at a bottle which had contained it. (Ibid) *”Alexander swallowed 4 scruples of saffron without perceiving any obvious efforts therefrom; and Wibmer took 3j without observing the slightest effect”(PEREIRA)*.
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.