11. Dr. KLINKOWSKI. – September 6th, 6 a. m. 5 dr. tinct. Immediately warm feeling all over body. – 7 dr. 10 dr., same warm feeling and increased activity of mental powers for 1/2 hour, giving place to sulky humour and disinclination to mental work. Increased urinary secretion. – 8th. 15 dr., same symptoms. These 2 days. 2 loose stools; his habit was to have a stool only every 3rd day – 9th, at night woke frequently with a start, followed by anxiety and sweat, especially on forehead. – 10. 25 dr., immediately feebleness of thinking faculty with sulky, restless disposition. At same time transient burning stitches in left groin; the glands there were swollen. E., besides the pain in groin, had pressive pain in left shoulder – joint, especially on raising arm. N. passed in tossing about in bed, with anxiety and sweat on forehead. – 11th. 25 dr., the stitches in left groin more continuous, the glandular swelling increased. The pain in shoulder-joint at first drawing tearing at last spreading all over left side of chest as a prickling sensation felt at all times. E., felt an annihilating sensation of moral weakness, so that for more than 1/2 hour he wept, and then fell asleep for 3 hours. 12th. As the inguinal glands was greatly swollen, and the pain in shoulder continued, he felt at all times. E., felt an annihilating sensation of moral weakness, so that for more than 1/2 hours he wept, and then fell asleep for 3 hours. – 12th. As the inguinal gland was greatly swollen, and the pain in shoulder continued, he left off the medicine; these symptoms grew slighter and were gone in 3 days., but the loose stools still continued twice a day for a considerable time. The urinary secretion, from being increased, became scanty. (Ibid, 371.)
12. Dr. W. LOW, from January, 20th, took daily 2 to 3 dr. of tinct. -28th. There occurred a most unusual mental state; he felt as if oppressed by some secret grief or vexation about some disagreeable event, and the foreboding of some coming disaster. 27th. Woke tired, as if he had spent the night in dancing, with oppression of chest and precordium. E., restlessness and oppression; good appetite; drowsy. – 28th. Woke uncomfortable after a restless night evening, very exhausted. – 29th. Woke by a burning – itching pain in right cheek and ala nasi. The painful part showed a circumscribed redness covered with small elevations. Towards evening numerous vesicles size of pins’ heads appeared on spot and neighborhood, with painful burning sensation. Little appetite and desire for repose. -30th. The vesicles grown the size of lentils. – 31st. A similar eruption on thigh with heat and itching. In spite of his depressed spirits the sexual desire was increased. ( Ibid. 373.)
13. Dr. A. VON MARENZELLER began his proving of the mother tinct. On June 17th, taking 4 dr. every other day. The symptoms observed were frequent sneezing with transient increase of nasal mucus, nocturnal headache, palpitation of heart, which occurred from June 17th to July 1st. He consider these symptoms as accidental. From 1st to 5th July he took every day 8 dr. As the above symptoms reappeared in still greater intensity, he was convinced that they were due to the drug. The most prominent of the symptoms was the headache, which came on invariably soon after midnight, and woke him up repeatedly. It was a pressive pain in occiput extending to nape, and toward the front of the head, like what occurs after taking too much alcohol; sometimes it was as if the head had been in a bad position, at the same time palpitation of heart which prevented lying on left side. During the day frequent sneezing as if coryza were about to come on, with transient increase of nasal mucus, sometimes cough with expectoration of mucus. These last symptoms lasted about 1/2 hour, then went off and recurred about 6 times during day last 2 days there was unusual weakness, drawing tearing now in left now in right leg down tibia to ankle; single more violent tearings in right fringe – joints, especially when moved; frequently tickling in urethra, especially in fossa navicularis, also several pimples on the face, which he had formerly often suffered from, but not for a long time previously. Appetite was rather increased than diminished. The head symptoms lasted, though in diminishing intensity, for about 6 days after leaving off drug. (Ibid. 374.)
14. N. N-, medical student, aet. 25, had had in childhood measles, two attacks of scarlatina, the second time with general dropsy. From October, 1853, to beginning of 1856 had suffered from frequent attacks of indigestion accompanied by intolerable headache especially in left temple, great irritability, tendency to melancholy, some feverishness, great weakness, and faint feeling. – August 10th. 4 dr. tinctation for several minutes and tensive sensation in stomach. – 11th. 6 dr., same symptoms but more severe. – 12th. 8 dr., the eructation continued loner, with pressure in stomach and tension of whole abdomen, going off in forenoon; he was excited, cheerful; less sleep than usual, vivid stools hard, scanty. – 13th. 10 dr. eructation, slight tension of stomach, excitement continued. 10 p. m. disagreeable pricking sensation in right inguinal gland for 10 minutes. Sleep uneasy. 14th, 12 dr.; except excitement, none of the other symptoms. E., great pain in right inguinal glands and transient pain in right axilla, restless sleep. – 15th. No med. M., remarkable swelling of both inguinal glands, which are painful on walking, great headache, weakness, prostration, furred tongue; depressed spirits and drowsiness. – 16th. No med. R. inguinal gland more swollen, pain in it prickling but not lasting long, increased when walking or when in bed, great prostration, diminished appetite; no stood; left inguinal gland a little swollen. – 17th. 14 dr., swelling of right inguinal gland was in evening more conspicuous both to sight and touch; no pain, only tensive feeling when walking. The drowsiness and weakness continue, but appetite returned. – 18th. No med. Same symptoms. – 19th. 16 dr. during day frequent eructation, distension of stomach and abdomen, swelling of right inguinal gland very conspicuous, pain only when walking. – 20th. R. gland still swollen, left still a little; considerable headache, no stool, diminished appetite, weakness, drowsiness 21st Felt unwell. Same symptoms. 22nd. Gastric symptoms and headache better after stool; inguinal glands as before. – 23rd. Inguinal glands unaltered, otherwise better. – 24th. Inguinal glands the same tension in them when walking. – 25th. 18 dr. – 26th. 20 dr.; no increase of glandular swelling. The glandular swelling continued unaltered for 4 days longer; it then began to decline and was gone on the 10th days., but the tensive feeling in that part lasted other 2 days. (Ibid. 376.)
15. Dr. JOSEPH RAIDL, aet. 47, in good health, on May 7th, 5 a. m., took 5 dr. mother tinct; no effect. 8th, 5 a. m., 10 dr. No effect. – 9th, 5 a. m., 20 dr. Afternoon, slight sensitiveness of hairy scalp, on a spot the size of half – a – crown on right side, also slight itching in inner canthus of right eye. – 10th., 6 a. m., 30 dr. The sensitiveness of scalp extended over whole front of head, and was more intense, the itching and burning in right canthus increased and extended to left inner canthus. – 11th. 30 dr., same symptoms, and in addition drawing pain on right side of forearm from elbow downwards, combined with difficulty of moving it. Felt very sad, no inclination to speak; sleep restless at night – 12th, morning, felt very exhausted, the sensitiveness of scalp continued; there were yellow crusts in inner canthus. 5 a. m., 40 dr.; in addition to the former symptoms, violent itching in hairy scalp, the epidermis there came away in bran – like scabs; as if a veil before eyes, the letters disappeared on reading, sometimes quite dark before eyes; great prostration, little appetite, very sad. at night little sleep, dreams of unfortunate occurrences. – 13th, morning all the former symptoms, but spirits better. afternoon, stitches at base of glans penis, itching in fossa navicularis, frequent call to urinate and erections of penis, and fossa navicularis, scaling of epidermis continued. – 15th, morning 30 dr. No new symptoms, nor yet on the 16th, when he took 30 dr., only the itching of scalp and scaling of epidermis were observed. – 19th. Four inflamed cutaneous glands in left thigh. During the next 14 days several more such inflamed gland appeared in different parts. They appeared as deep – red pimples the size of millet seeds, with a red areola; many of them gradually disappeared, others became filled with thin pus. From 20 to 24th, every morning 20 dr. of 1st dil., which caused no symptoms. – 24th. Felt in both groans a disagreeable tension, and the glands were swollen. – 25th. 20 dr. 1st dill during day slight stitches in fossa navicularis, inguinal glands continued swollen, and also on 26th. – 27th. Noticed on his shirt three small spots made by discharge from urethra. After standing for 2 hours, chiefly on left foot, felt more tension in left inguinal region, and the following evening increased swelling of left inguinal gland. During next 4 days the swellings began to diminish so that on June 2nd only the left gland remained slightly swollen; after 2 days no more urethral discharge, but the inflamed cutaneous glands were still there, and the cutaneous nerves were very sensitive to cold and the friction of the clothes. No more medicine was taken during june. – 3rd. About 3 p. m. such exhaustion an weakness he had to go to bed. Then there came on heat, headache, great thirst, pulse 100, urinary secretion very scanty and dark coloured; night very restless. – 4th, morning felt better, and could get though with difficulty. After dinner great weakness, heat, etc. as before. So it went on till 8th, when after profuse sweat the previous night and much chloride found in urine, he felt much relieved. – 9th. Very weak. At night very restless, recurrence of the heat, headache, thirst, and all the former symptoms with increased intensity, so that on 11th and 12th he was delirious during the evening exacerbations. From this time till 24th felt as if the skull were too small for the brain; the sensitiveness of scalp returned, and also the scaling of the epidermis. Inflamed cutaneous glands appeared on face, and upper and lower extremities, which often went on to suppuration. During these days he had great thirst, suppressed cutaneous secretion, rare stools, the sp. gr. of the urine ranged between 1024 and 1026, the pulse between 90 or 100. Great weakness, restless sleep,
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.