without date, heavy pain in head as if great weight lay on vertex, with great prostration and weariness, pain diminished by pressure, increased by sound of talking or any other noise; heavy pain in forehead lasting d. and n. for 2 successive d., increased by strong light and by sound of loud voices or noises; pain and drawing in occiput, increased by moving head, relieved by bending head backwards; painful drawings in muscles of l. chest, which extend to shoulder-joint and impede respiration and free motion of arm; nervous palpitation of heart, much augmented on occurrence of catamenia; constant and annoying pulsation in coeliac artery; heavy feeling in stomach; insupportable irritation in urethra as if she should make water constantly; urine reddish, turbid, very abundant, on cooling depositing red sand; painful constriction in groins extending round pelvis; general weakness, so that she cares not to do anything, speak, stand, or walk across room. [ The symptoms without note of time were omitted in our former presentation of the drug, as we had no assurance that they were not clinical only (which 40 symptoms in the list obviously and avowedly are). EDs.
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.