All that is known concerning the medications for anterior pituitrin in potency is based on a study of its function as an endocrine and the symptoms produced when the extract is given in toxic doses or the gland itself has become diseased. As far as I know, it has never been proven.
It is well known that mal-function of the pituitary is one of the causes of obesity. Sagas (Analytical Cyclopedia of Practical Medicine) is of the opinion that this gland governs, by way of the spinal axis, the functions of the sympathetic nervous system, and through this, among other organs, the thyroid and the adrenals.
Thus deficiency of its secretion may result in a diminution of the secretion of the thyroid gland also; and with the obesity, there may be deficiency of its secretion may result in a diminution of the secretion of the thyroid gland also; and with the obesity, there may be deficiency of nutrition of the skin and nails,I shall not go into this further, but merely state that I reached my decision in the selection of pituitrin on these grounds, and also on the fact that a high potency of a drug may antidote its ill-effects when given in crude form. the case of Mrs. R.B.C., age 46, is not only an example of the action of a remedy according to the well-known tenet that cure is from within outward, but may provide a future basis for the application of this endocrine in disease.
July 13, 1945-The patient is light completed,blue eyed, weight 199 pounds, too heavy for her height, which is about 5 feet 6 inches.she has been ailing for ten years and has been under the care of at least two old school doctors, whose only medication was endocrines and pain killers. During most of this period she took ten grains of thyroid daily with only a few short periods she took ten grains of thyroid and posterior pituitrin was yielding the best results.
Cheerful, as a rule; laughs too readily but inclined to week; at times spells of melancholy in the evening after going to bed, accompanied by nervous tension and anxiety as if she had to hurry. This may have been a drug symptoms because it was accentuated by the thyroid.Weakness with drowsiness, also, made worse by the thyroid tablets.Perspires profusely and on slight exertion. Sensation of intense heat recurring every four hours.
Severe headaches starting in the shoulders and back of the neck, at times reaching the vertex. Ameliorated by heat. Eyes focus slowly. For many years recurring, abortive styes. Appetite poor. Craves fruit and juicy things.some thirst for cold water but it is apt to chill her. Frequent, explosive, copious stools after meals, from milk, or from apparently no cause. Stool preceded by sadness and chilliness which are relieved afterwards. Involuntary escape of urine on coughing or sneezing for many years. Interscapular lameness and stiffness, especially turning in bed, for the past two years. General sore, bruised feeling, bruises easily, small wounds slow to heal.
Menses moderate in amount and of short duration. Nails ridged, brittle; finger tips crack; inflammation, soreness and swelling at the base of the nails. Irritation, burning and redness between the fingers and on the palms, which are dry, scurfy and inclined to crack- this since she was thirteen years of age, always accompanied by dryness of face and lips, and stiffness of the hands, aggravated in the morning,better as the day goes on. Ameliorated in the open air, but dreads the cold; is always chilly, worse even from uncovering the head or hands, Rx, Anterior pit 200, one dose.
May 16, 1945-Improved, but symptoms returning.Rx. Anterior pit.200.
May 30,1945-Much better in every way except that she lacks energy. A black ulcer, three inches in diameter, due to the coalescing of several sores due to the hypodermic needle, is healed, all but a small spot which still oozes purulent fluid.Rx. Sac. Lac. all but a small spot which still oozes purulent fluid.Rx. Sac. Lac.
July 16, 1945-Backache, but only while in bed. Has gained twenty-one pounds since July.Rx. Sac. Lac.
August 5, 1945-Rx. Anterior pit. 200.
October 4, 1945-Rx. Anterior pit.10M.
November 4, 1945-Has been unusually well for her. One or two attacks of diarrhea from no apparent cause. Backache worse Eyes focusing more readily.No gain in weight. Walked six blocks, stood for awhile and walked back again-has not been able to do this for seven years. Rx.Sac. Lac.
November 22, 1945-Pains in knees, hips,and sacrum (an old symptom). Has gained weight but feels better in general. Rx. Sac. Lac.