Clarke gives the toxic effects of homeopathy drug Acetanilidum and its therapeutic uses in non-toxic doses in his book The ABC Manual of Materia Medica and Therapeutics, published in 1901….

      The ABC Manual of Materia Medica and Therapeutics By G.H.Clark. Acetanilid.


      Hyperpyrexia causing spasms and other untoward symptoms, especially in children. Headache from exhaustion or nervous excitement. Sleeplessness and loss of nervous control from exhaustion. Pains of dysmenorrhoea. Pains of inflamed nerves, as in optic neuritis, herpes zoster, etc.


      Depression of the nervous system, heart and respiration. Headache, nausea, malaise, mydriasis, deafness and ringing in the ears. Difficult respiration, cyanosis, rash, coldness of the extremities, cold sweat, collapse. General analgesia. Anaesthesia.


      Adult, 3-5 gr.

Child under twelve years, 1-3 gr.

Child one or two years old, 1/2 gr.

Dissolves in alcohol, not in water. For fever a dose every three or more hours. For pain two or three dose may be given at intervals of half an hour, but thereafter not more often than once in three hours. Great caution must be observed when prescribing this drug for patients ill with pneumonia this drug for patients il with pneumonia, typhoid fever and other diseases in which embarrassed circulation and low vitality are marked. In this class of case the benefits derived are more than problematical.

An effective method of administration is to thoroughly triturate with an equal weight of granulated sugar.



Febrile affections of children.

Spasms in children, caused by hyperpyrexia or by erethism. Acute and chronic articular rheumatism.

Neuralgic pains of inflamed nerves as in optic neuritis, herpes zoster and traumatic sciatica.

Pains of cancer.

Of great service in dysmenorrhoea.

Pains of locomotor ataxia.

Headache from excitement or exhaustion.

Headache from ocular and other strain.

Sleeplessness from nervous exhaustion.

Loss of nervous control from exhaustion.

Tremors produced by multiple sclerosis.

George Hardy Clark
Clark, George H. (George Hardy) 1860-1941 was the author of: Homeopathic Treatment of Asthenopia; Lee and Clark's Cough and expectoration : a repertorial index of their symptoms; The A B C Manual of Materia Medica and Therapeutics; A system for the care and training of children; The Black Plague and Its Control.

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