Apomorphine



Pulse 108, respiration 16.

9.40.

Pulse 116, respiration 16; some nausea.

9.45.

No change.-9.50.-9.50. Pulse 108, respiration 14 to 16; nausea ceased.

10 o’clock.

Pulse 100, respiration 14.

From this time patient felt as before; no inclination to vomit.

The medicine seemed without effect.

Next day, no change; fever quite considerable; evening temperature 39.2 0, morning temperature 38.4 0; no stool; tongue coated; inclination to vomit. 9 A.M.

Pulse 96, respiration 14; twenty milligrammes Apomorphine taken by the mouth; same preparation as yesterday.

9.5.

Pulse 112, respiration 16; nausea.

9.8 Pulse 120, respiration 22; copious bilious vomiting.

9.10.

Pulse 92, quiet; respiration 20.

9.15.

Renewed vomiting, less copious than at first.

9.20, quiet; respiration 16.

9.30.

Quite, but no sleep; patient feels relieved; headache, which before the first vomiting was most intense, has now almost entirely ceased.

11 o’clock.

Pulse 92, thermometer 38.6 0, respiration 14; no movement of the bowels during the day; at night one very difficult stool.

Next morning, although the tongue was less coated and the headache better, a saline purgative was prescribed. Perhaps we should have obtained better results from a dose of three centigrams Apomorphine.

Case VII.

(Communicated by Dr. Zuber). Hemoptysis from tubercle.

Injection of three centigrams Apomorphine; copious vomiting in four minutes.

Leon S., second-class trooper in the second regiment of artillery, 23 years old, of mean appearance, was attacked, on the 22d December last, with a troublesome hemoptysis.

When I saw him it had lasted four hours; the blood raised was bright red, frothy, almost pure, and quite abundant (four hundred or five hundred grams); cold fomentations had been applied to his chest, and he had taken two tablespoonfuls of salt; pulse frequent, 104.

It was necessary to arrest the bleeding as soon as possible.

I thought of resorting to the use of emetics, so highly recommended in such cases, and I selected Apomorphine, whose properties as a speedy emetic made it particularly applicable.

At 5 P.M. I injected under the skin quite a large dose of Apomorphine, three centigrams of slightly altered solution (colored light-green); the patient went on coughing, and at each paroxysm he brought up blood having the same appearance as before.

5.4.

Abundant vomiting of food, without previous nausea; this lasted about two minutes; then came a period of quiet, when cough no longer racked the patient; in half an hour the vomiting ceased; the patient was extremely feeble, but the means employed appeared to have done good service; he coughed only at long intervals, and the expectorated blood become less and less.

Next day, there was hardly a trace of blood in the sputa; haemoptysis was probably owing to a tuberculous induration at the apex of the right lung; no local effect.

Case VIII.

(Communicated by Dr. Zuber). Angina tonsillaris.

Injection of two centigrams Apomorphine; vomiting in three or four minutes.

M. T., sculptor; sick for three or four days with acute tonsillitis; he was very subject to angina.

At Rome, where he was an art student, he had several attacks, one of which, of a phlegmonous nature, caused him much suffering.

Moreover, during a residence in the Campagna, he contracted an obstinate intermittent, which still lingered, and imparted to the fever accompanying his angina a decidedly remittent type; the tonsils are entirely swollen, they greatly impede respiration, and deglutition is almost impossible.

I made two free incisions into each tonsil, with a view of depleting them; and, at last, to aid this effect, I thought of administering Apomorphine, since it was exceedingly difficult for the patient to get down a dose of emetic.

I injected, accordingly, two centigrams of a recent solution; nausea came on in three minutes, followed by vomiting, which the conditions of the pharynx rendered very difficult and painful.

The vomitings, which were quite frequent, ceased in half an hour.

As I anticipated, the muscular contractions strongly favored the escape of blood from the engorged tonsils, through the previous scarifications, and the patient soon felt comparatively easy.

I prescribed emollient gargles, and a draught containing seventy-five centigrams of quinine.

Next day, there was considerable improvement; fever less intense; the tonsils, though still much enlarged, now allowed air and warm drinks to pass easily.

M. T. considered himself cured, and could not sufficiently praise the new emetic.

“At Rome,” he said, “they vomited me a great deal, for they used to precede quinine by an emetic, but the effect was never so speedy.

Here the business is over before ordinary emetics would begin to operate”.

TF Allen
Dr. Timothy Field Allen, M.D. ( 1837 - 1902)

Born in 1837in Westminster, Vermont. . He was an orthodox doctor who converted to homeopathy
Dr. Allen compiled the Encyclopedia of Pure Materia Medica over the course of 10 years.
In 1881 Allen published A Critical Revision of the Encyclopedia of Pure Materia Medica.