An alkaloid obtained from the decomposition of morphine by means of hydrochloric acid. Formula C17 H17 NO2. For use, the alkaloid is triturated with sugar of milk.
The chief interest attached to this substance lies in its remarkable power to produce emesis (which it does in doses of from five to seven milligrams in adults). This irritating action upon the nerve centre is similar to that of Sanguinaria, Veratrum, Ipecac., Copper and Zincum met.
Pandiculations. Depression. Faintness Weakness; with sweat on face, which was pale so that eyes closed involuntarily.
Aching. Heaviness. Vertigo; with chilliness. Dullness, sometimes described as headache, sometimes as heaviness or vertigo, often with roaring in ears and feeling of heat, at times sudden anxiety in praecordial region and pressure in chest, with the reaction there is generally inclination to sleep, prostration and in a few cases nausea and retching without warning, the relaxation during the prodromal state was very great, with sweat, salivation and paleness, especially of face, the vomiting is easy, or after the stomach has been emptied difficult with eructations and retching, between the acts of vomiting the patient is quiet, weak, yawns and perspires, sleepy after the vomiting ceases.
Injection of conjunctivae and lachrymation. Pupils dilated. Face red; pale. Salivation. Violent inclination to vomit. Vomiting; without previous nausea; easy of water as it was drunk,. also milk. Retching; as soon as stomach had been emptied. Weight at stomach. Respiration irregular; rapid. Pulse rapid and irregular; rapid small and soft Extremities heavy; weak. Inclined to yawn. Sleepiness, with sweat. Sleep. Heat running suddenly all over body, then vomiting. Hot feeling all over body., specially in head. Sweat.
Clinical The applicability of this drug to the relief of various troubles requiring prompt emesis will be apparent to every one. (Its use poisoning by Opium is dangerous). the hypodermic injection of 16/1 of a grain will cause full emesis within 5 to 15 minutes in an adult. It has been found useful in vomiting of various sorts, sometimes with violent spasms, and empty retching and headache, sometimes and heartburn, pain between shoulder blades; sometimes it has cured the vomiting of food, sometimes palliated the vomiting of pregnancy or uterine displacements or uterine tumors, sometimes relieved seasickness; in one case the 2nd trit. cured. vomiting which has lasted several days without any organic disease, apparently of nervous origin.