Pulse, extremely small, scarcely perceptible, though normal in frequency, very frequent.
Back
Pains in back like after-pains.
Limbs
Prurigo on wrists and bends of knees.
Lower Limbs
Gangrene of one foot necessitates amputation.
Generalities
Pale and listless. Anaemia. Profound adynamia. Collapse. Convulsions. Muscular contractions. Very painful cramps in trunk and limbs.
Skin
Pronounced jaundice, skin saffron yellow. Pruriginous eruptions, or redness and itching, at wrists and bends of knees.
Sleep
Great desire for sleep.
Fever
Chilliness with the diarrhoea. Perspiring freely. Skin moist and cool, especially lower limbs. Forehead covered with cold sweat.
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