10. Another woman after a few doses of same med. felt itching in vulva, dryness of throat, intense coryza alternating with stuffed cold in head. (Ibid.)
11. After 1 dose a woman felt almost immediately acute pains in right lumbar region, m. The next day in the m. expectoration of a mass of thick, viscid, tenacious, bloody mucus, with violent expulsive efforts accompanied by inclination to vomit. (Ibid.).
Poisonings
I. A cook used some of the chloride by mistake for salt. Several guests partook of the soup and other food so seasoned. They were seized with colic, which in two persons lasted 2 days, and was accompanied by diarrhoea. None had vomiting. (ORFILA, toxic., sub voce.)
2. T. A. E -, aet. 14, swallowed a solution of the bichloride. He felt great pain at stomach, and vomited a quantity of thick slimy mucus of dark green hue. His mouth and fauces were much congested, he could scarcely swallow, and his mouth felt hard and leathery. Free emesis was induced. A cold clammy sweat broke out, and pulse was indistinct and fluttering. Strong reaction ensued, with severe pain and great soreness of stomach and bowels, as also of mouth and throat. It was some weeks before he had quite recovered. (HAZELTINE, Bost. Medorrhinum and Surg. Journ., xxxi, 38.)
3. MEINEL, from a solution of the chloride with common salt, saw pain in praecordial region and hiccup, with vomiting of similar matter as in II, 2, followed by hot and dry skin with pulse at 100. (Schmidt’s Jahrb., lxxiv, 167.)
4. A family ate a cold chicken pie baked the previous day in a new tin pan. All had violent pain in epigastric region and frontal headache, loss of appetite, and yellow tongue: with some there was constipation, with one a severe attack of something like dysentery. Dr. Angell, who attended them, ate of a similar dish very heartily as a test; it brought on most distressing debility, almost preventing his riding home, a distance of a few miles. Another family who ate a custard similarly cooked were affected like himself. (Ohio Medorrhinum and Surg. Rep., ii, 152.).
Experiments on animals
I. ORFILA found that a solution of 6 gr. of the chloride injected into the jugular vein of a dog killed it in 1 m.; that 2 gr. caused tetanus, and death in 15 m.; and 1/2 gr. death in 12 hours, the only symptoms being somnolency and catalepsy or fixedness of position. When swallowed, however, dogs required 18 – 44 gr. to kill them – in 1, 2, or 3 days, efforts to vomit and great depression being the only symptoms; after death stomach was found excessively inflamed and sometimes ulcerated. 3ij applied to a wound caused violent inflammation and sloughing of the parts, and death in 12 days, without any internal symptom during life or appearance after death. (Opium cit.).
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.