28. L.L. BRAINARD took 4 doses of 30th without effect. Nov. 11th. – Took 3rd trit. at 5 p. m. 6, expansive sensation in top of head. 10, slight aching pain in left eye. 12th. – Awoke with aching pains in whole brain, worst on left side; same at back of orbit, extending into brain, worse on reading (so that he must stop), causing nausea; pulse 72, full; chills in paroxysms. A further dose on 14th, and one of 1st trit. on 19th, produced no effect. (Ibid.)
29. J.W. R – (a woman) took 3rd trit. at 3 p. m. N. restless; pain in right deltoid, only relieved by violent motion. On 2nd day similar pain in arm. N. again restless, and she woke with dull heavy headache over yes, which passed off on rising. Third n. again restless, and on 4th day, evening, felt soreness and pain at umbilicus, which on examination was found much inflamed. It continued thus 4 – 5 day, growing less gradually. On June 15th took another dose. Felt nothing till 8 p. m., when there came on deep pain in muscles of right forearm and wrist; also pain with sharp stitches in ball of right eye and in frontal bone, with a distinct pain running obliquely into temporal bone. 16th. – Return, evening, of pains in eye and arm; former relieved by motion in open air. (Ibid.)
30. a. Dr. W. H.TITUS took gr. 1.1/2 of 3rd trit. m., Felt nothing during day, but woke next m. with bad taste in mouth, teeth feeling rough. While at church in forenoon was taken with chilly sensation in back, and soon began to yawn and feel bad; joints felt bruised; every movement and every draught of air made him shudder. Pulse was 93, temp. 100o. Throat now began to be sore on right side at small spot; profuse salivation followed, and pain in top and forepart of head. This increased till he had to lie down. He could readily count his pulse by the carotids, and hear the two sounds of the heart as his head lay on the pillow. Soon began to have backache, which kept him restless in night; pain seemed in region of kidneys, and he passed large quantities of colourless urine. No position favoured pain in back, but head was relieved when he sat up in bed; strong pressure also relieved, and walking, but this he had not strength to continue long. Next day pain in bowels, which seemed distended with gas; darting pains in joints, more in legs than arms, extending upto into body; felt great anxiety about friends at home, could not get them out of his mind; could sit up only a short time, when he would be compelled to lie down again, on account of pain in bowels; pain in knees when flexed them; throat still sore on right side; urine profuse and very clear. On 4th day noticed left eye red and swollen; submaxillary gland was tender and tumefied. Pain and flushing of face on rising from sitting position; strong – smelling sweat about genitals, prepuce tender and swollen, with a number of small vesicles on glans penis, causing burning – itching sensation (these disappeared in 48 hours). Petechial eruption on back and arm, size of fleabites; darting pains about body; tongue coated white, with oily feel and bad taste; curious feeling in face, extending to neck, like cramp, – at time when this was worst. hand became quite numb, and it bothered him to hold anything. By next day all troublesome symptoms had passed off, and he began to have good appetite – this having quite failed during proving.
30b. Took 3 more doses in Jan., and again in Feb., with same symptoms, but less well – marked (there was no eruption.) (Ibid.)
31. A.P. McDONALD, Dec. 29th, at 7 a. m., took dose of 30th 6:30 p. m., severe pain in right eyeball, darting from within outwards, relieved by pressure o eye, continuing at intervals till 10, when they seemed to shift to supra – orbital ridge, and continued so till about 12. 30th. – On rising same pains in both eyes; they went off after breakfast, but returned in left eye when he sat down to study in evening; relief from movement. 31st. – Frequent paroxysms of twitching in vastus externus (lower 3rd), coming on every time he sat down during d. On Jan. 16th took another dose without effect. (Ibid).
32. W.S. WILLIAM took 30th at 2 p. m. At noon of following day chilliness in right back; vomiting of acrid fluid; slow digestion; continued yawning, with drowsy feeling all day; severe colicky pains in left abdomen; neuralgic pain in right face; dull pain in both temples, with pressing outwards in frontal region. Next day head felt as if falling forward; vertigo; he stumbles on going upon down stairs; sharp pain in supra – orbital region, running off towards nose. Back very weak, unable to stand erect; dull pain in it, with almost constant desire to urinate, passing large quantities of reddish urine, oppressed breathing. Back continued weak for another day (Ibid).
33. [ These provings (33-36) represent the only results obtained from 14 students taking the 3rd trit. and 6 taking the 30th ] Mrs NICHOLS took 1 gr. on 30th at 3 p. m. one Monday. In 15 m. brassy taste and increased saliva, which continued rest of d. In evening cough from tickling in throat. Tuesday – Had slept better than for 6 mo. before. Took 1 gr. Felt quite exhilarated during m., very gloomy towards noon. At 1 took another gr. 3, felt as though stomach swelled, continuing rest of day 4, hard sore pain in splenic descending to inguinal region and across hypogastrium, quite severe and increased by motion. In evening pain was so severe it caused her to extend legs. Took 2 gr. before retiring. Slept soundly. Wednesday – Took 1 gr. in m. Had bad taste all day; paroxysms of burning in palms; soreness in left side and hypogastric region, hurting her to stand. 4 p. m., took 1 gr. Tongue felt sore on tip and rough; throat full; stomach pressed; sore pain in spleen for 2 hours; eyes smart, lids sore. In evening, hammering in right ear, while external ear felt as though hot air were blowing on it. Took another gr. before going to bed, and another on Thursday m. While writing, pain in right ear; tongue dry, rough, and sore. P. m., pain at left of sacrum. This last felt on Friday m., and headache Friday evening and Saturday m. No symptoms afterwards. (Ibid.)
34. C.S. COLLINS took 1 gr. of 3rd trit. Monday e. After 3 hours dull pain in region of heart, lasting nearly 1 h. On Tuesday m. 1 gr. 10 a. m., pain in back of neck reaching to first dorsal vertebra. 3 p. m., pressure on top of head; hot cheeks; eyes suffused with tears. 9, took 1 gr. On Wednesday repeated dose at 8 a. m. and 9 p. m. At 3 p. m. very sleepy, hardly able to keep awake, until relieved by sleep. On Thursday m. awoke with stitches in left breast, and unable to draw long breath. This continued all day, and was so uncomfortable that no more medicine was taken. On Friday pain was gone (Ibid.)
35. L.KENNEDY. On 2nd day after beginning 3rd trit. slight contraction in region of stomach. On 3rd day this feeling was more plainly marked, continuing 4 or 5 day, attended with dull pain in left side and forepart of head, not relieved by food. Appetite as usual. Symptoms began to diminish on 6th day and had disappeared by 8th. (Ibid).
36. Mr. DILLINGHAM took 3rd trit. for 4 day (Jan. 8th – 12th), and notes following results: – Pain over right eye all evening of 8th; dully heavy headache in forehead before rising on 12th. Bright marks when looking at an object; dark yellowish spots on book when reading, covering one or two of the letters. Singing in ears, like escaping steam, after lying down at n. Nose stuffed and hot (8th.). Face flushed and red (9th). Smarting of end of tongue; it feels as if burnt by hot liquid. Hunger, but can find nothing to satisfy it (12th); food has a flat taste. Stool irregular and loose; anus sore, disposed to protrude (as if from relaxed sphincter); return of piles, which have not troubled him for 3 years. Frequent desire to urinate, often ineffectual. Cannot fill left lung, as inspiration causes dull pain in its apex, relieved by pressure; stitches under inferior angles of scapulae during expiration; slight constant inclination to cough from filling lungs. Cramp – like stitches up and down spine; stiffness of left neck. Wrists feel weak, dull aching pain in them; hands first cold, then hot and red. Numbness in left foot. Unduly profound sleep. Perspires very easily. Pulse, normally 60 – 65, during proving was 74 – 83, at first full and strong, then weak. (Ibid.)
37. A woman took powder of 30th, Oct. 25th, at 11 p. m. Next m. in church had dull temporo – frontal aching in fits, with tension of skin of nose and forehead. Felt little of it during day, but again at church in evening it came on, preceded by dizziness in passing people, and accompanied by nausea, heat in face and down back, with chilliness of legs, and lasted till bedtime. 27th. – While taking m. bath sudden stiff neck, right side, which lasted badly all day, involving ear, shoulder, and even chest of same side. 28th. – Stiffness almost gone, but headache recurred from 1 to 6 p. m., with great sleepiness, and hung about her for 2 or 3 day more (Ibid.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.