15a. Dr. HAMILTON RING, aet. 29, light hair, took, Jan. 14th, 20 pellets of 30th dil. at 4 p. m., and on 115th also 20 pellets of same dil. at 9 a. m. In course of 15th he experienced on bridge of nose a sensation similar to that which is produced by touching it with a metallic substance. Sticking pain about punctum lachrymale of upper left eyelid. Next day he noticed a small pimple (like a transparent vesicle) sore to touch, on the inner edge of the eyelid, near the spot where the pain was, which latter had disappeared. 17th. – 10:30 a. m., took 30 pellets of 6th dil. Soon after, aching and somewhat sharp pain in left hypochondrium, in front, over a space as large as may be covered by the hand; worse on moving about and in open air; soon extending around lower border of ribs behind, and to region of left kidney, where it seems dull and somewhat pressive (all felt and disappeared in 4 hours). Soon after this same pain came in right hypochondrium, in front and extending around to back, and region of right kidney, where it is of the same character as in left kidney. The dull pressive pain is felt in one and then in the other kidney alternately. The pains intermit in severity, and those in the hypochondria are relieved by bending forward. Occasional flashes of pain in right temple from front backwards (organ of mirthfulness). Soreness in the roof of the mouth. Heaviness in head, desire to sleep during day, restlessness at n., indisposition to mental exertion. (The above symptoms appeared nearly if not exactly in the order in which they are written.). 18th. – In evening occasional shootings in upper part of left temple along temporal ridge; dullness in whole head, especially in forehead just over eyes, lame sensation in right shoulder – joint.
15b. 19th – At 10:30 a. m. took one powder of 1st trit. (cent.), after which the following symptoms were experienced: – An hours after, uneasy, creeping, and pressive sensation about ossa nasi, lasting about an hours; it is the sensation experienced by most persons on putting on a pair of heavy spectacles, if not accustomed to wear them. Also for a short time pain and sensation of fulness in meatus of left ear. In evening sensation of approaching looseness of bowels. Itching on various parts of body, while walking in open air. 20th. – In forenoon head full; nervousness and irritability about noon for a short time; also, for a short time, sticking pain in back part of left knee – joint; in afternoon slight pain in right knee – joint (similar to pain in l.), with creeping sensation above and below it, seemingly about bone, lasting about an hours (during day itching over body). 21st. – Frequent itching over the body, and itching and sticking in internal and external canthi; head full, heavy, with strong pulsations of temporal arteries; great inclination to sleep during day 22nd. – Itching on body and in canthi, as before; a spot on right side, between ribs (7th and 8th), as large as a wafer, very sort to the touch, with occasionally sore pain in and around it; head less heavy than the day before; sore spot on tip of tongue. 23rd. – About 4 a. m. was awaked by dull sticking pain in region of left kidney, which lasted but a short time; afterwards tossing about and sleeplessness for an hours; after rising from bed fulness and pressure in occiput and back of neck, continuing with much severity till about noon, after which the symptom somewhat abated; heaviness and sleepiness during day; pains of short duration in right hypochondrium, in middle of left breast, in front of left kidney, in occiput; itching over body at times. In evening, sticking pain in the region of left side of 5th and 6th dorsal vertebrae; sore spot in right side has continued, with the characteristic symptoms before mentioned; during day there were pains at corresponding spot on left side of same character, but without a sore spot. 24th. – Occasionally sticking pain on right side of same dorsal vertebrae (5th and 6th); pain sometimes in left side of occiput (organ of amativeness); itching of eyelids and of various parts of the body; sore spot in right side continues. The pains in knee – joints, mentioned as having been experienced on the 20th inst., have been occasionally felt in a slight degree every day since. The sore spot on right side continued 3 or 4 d. The itchings in various parts of body and in the canthi of the eyes were felt for 5 or 6 d. The dullness of head and unfitness for mental exercise have not, after the lapse of a week, entirely disappeared. The severest pains experienced were those in the hypochondria and kidneys. The pains mentioned as felt on the 23rd and 24th, on the side of the 5th and 6th dorsal vertebrae, have been occasionally felt until the 27th. Has been disposed to costiveness during the whole time of taking the medicine. On 27th after dinner had feeling of weight in lower part of rectum and a sensation like aching. (Ibid).
16. Dr. C.E. TOOTHAKER, of lymphatic nervous temperament, light hair, general health good. (In childhood affected with rachitis; in youth with burning sensation in chest, with colic in umbilicus and stomach. Subsequently he had pains in the face, itching and burning in throat and roof of mouth. At present ringing, humming, or roaring in ears, with frequent itching sensations over whole body; slight dull pain in back of head and neck, sense of dull pain in one or both ears. Some remains of a former severe chronic bronchitis, causing frequent hawking and spitting, with thick pus – like mucus in m. Disposition to flatulence in bowels; passes water frequently. Frequent sleepiness when sitting. Languor.). Jan. 18th, 1851, 9 a. m., took 30 pellets of 5th dil.; 6 p. m., sensation of soreness on left side of root of tongue on swallowing, accompanied with roughness and stiffness, continuing through n. 19th. – At 9 a. m., took 30 pellets more; 10, slight pain in sinciput. Sense of elevation on walking in open air; never felt better in his life; like effects of a cordial. At 8 p. m., after tea, peculiar metallic taste in mouth, not much unlike sulphate of zinc, or the taste felt after a metal or salt, continuing more or less I hours 20th. – 5 a. m., peculiar agreeable sensation of exhilaration, and of fulness extending from all sides of chest, particularly thorax, towards stomach and heart, accompanied or followed by similar sensation in all the joints, continuing with intermissions till 8. Occasional pain in sinciput. Peculiar drawing in mouth after rising until breakfast. A small sore on right side of tip of tongue, also one on each lid, continuing several day 2 p. m., sensation in mouth has continued since 8, modified by continual tendency to hawk and spit, with unusually large flow of saliva and mucus; also sensation of warmth under sternum and sense as if secretions were flowing from stomach and all mucous surfaces, as well as from salivary glands. A peculiar nervous thrill pervading whole frame, even to fingers and toes, affecting specially joints. Sense of languor and depression, as if following excessive exhilaration or as after intoxication. The above sensation continued with intermissions for 3 d. In the eyes for 2 day excessive itching of inner canthi for considerable time from 6 p. m. From 9 to 12, itching in outer canthi, severe and frequent, with sense of stiffness in upper lids. In afternoon when sitting in house, sense as if a breeze of cold air were blowing upon eyes, very marked. Eyes very sensitive to cold air on walking out. Frequent pain in lower side of left knee, near inner side of tibia. Lameness and frequent stitches on walking, particularly on inner side knee – joint. (Ibid).
17. Dr. DANIEL WILDER, aet. 39, Jan. 13th, took 20 globules of 6th on going to bed. Restless uneasy sleep. 14th. – Took same. Increased restlessness, with constant dreaming; seemed to dream before getting asleep. 15th. – Pain in all joints with lameness during day; dull pain in forehead, which is cold, and is relieved by warm hand; aching soreness of eyes, worse in e. Pulse at noon 60, in evening 80. Aching soreness in teeth; regurgitation of wind from stomach; sores in mouth on under lip; severe pain in forehead, which lasts all night; great restlessness and nervousness. A good deal of mucus at posterior nares, which comes away in lumps. An eruption on inner and lower part of thigh, with itching. Unusual irritability during whole time since taking med. (Ibid).
18a. JOHN TURNER, aet. 27, nervous – sanguine temperament, took 20 globules of 30th dil. before going to bed, 14th Jan. Slept very well; had dreams, very vivid at the time, but could not remember them. Next day general nervous uneasy sensation, with depression. 15th. – 10 p. m., took 20 globules. Felt drowsy sensation as if he could sleep readily; went to bed at 12. Still had the drowsy sensation, and strong, very strong, desire to sleep, but could not sleep for disagreeable nervous feeling, which caused him to toss about in bed for 1.1/2 h. Sleep not as good as n. before; dreams vivid and rather pleasing, but on waking could not bring any one to recollection. (He dreams more or less every n., but thinks his dreams were unusual.) 16th – General morbid sensation of mind, rather disposed to be fretted at very little trifles, and not at all satisfied with himself, – in fact, thought that he was not at all amiable. At n. took 40 globules. Symptoms respecting rest, dreams, &c., as on 15th. 17th. – This day mental symptoms even aggravated; disposed all day to condemn himself for fretfulness and want of trust. Sexual excitement all day; general feeling of disorder in whole animal frame, but no particular symptoms.
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.