3. ESPE, aet. 36, took 10 dr. In 1/2 hours violent pressure in region of orifice of stomach; in I hours borborygmi, especially about navel; in 1 1/2 hours violent pressing in orifice of stomach; in 2 hours pressive pain in hepatic region; in 4 hours pressive pain in forehead, increased by heat of room, and dryness in mouth without thirst; anxious full feeling in chest; in 6 hours violent cuttings with painful gurglings in whole belly, followed by mucous diarrhoeic stools; in 11 hours digging pain in hepatic region and oppression of chest, with dull pain under sternum; in 12 hours, with frontal pressure there is lancination, as from thrusts with a blunt knife; in 14 hours difficult respiration, with pressive pain in pit of stomach; on Ist day, burning forehead, with pressive and burning pain, evening; belly tense, especially in region of liver, all evening; anxious sensation of fulness in chest, beginning 4 hours after dose, becomes stronger in evening; very sad humour; n. much agitated and full of dreams; next m., in bed, dull drawing pain in chest, increasing when he rises; head confused and heavy; pressure in stomach before taking food; hepatic region swollen, and pressure there causes a tensive pain; little sleep during 2nd and 3rd n. from dyspnoea and pressive pain in chest; on 6th day disagreeable hot sensation in throat. (Ibid.)
4. a. THEILE, aet. 24, took 2 gr. of alcoholic extr. In 1/4 hours headache, slight, transient, drawing, from temple to forehead; in 1/2 hours slight oppression of chest, sides and front, followed by sensation of heat in rest of thoracic walls; soon after, end of tongue painful as if burnt, and pricking under right arm. On Ist day slight sensation of burning in gullet, evening; on Ist n. sleep full of dreams, contrary to his wont; on 2nd day head confused in morning; acute drawing in right spermatic cord down inside of thighs; a cough with easy expectoration, which existed before the proving, becomes dry, squeaking, and painful; slight pressure under sternum, especially when hand is applied there. Without note of time, -horripilation as under all hairs. 4b. Same took 40 dr. of tinct. Soon, tip of tongue painful as if burnt (and 2nd d.). During first hours, in breathing deeply air does not entirely fill chest, without the least pain; on Ist day peculiar indescribable odour in nose, with similar taste in mouth; slept well, but had bizarre dreams towards m.; on Ist and 2nd day very frequent emission of urine, clear as water; frequent cough. Without note of time, -pricking pain under skin in nucha, which little by little fixes itself on a small place in right scapula.
4c. Same took 4 gr. of extr. For several day shooting in right axilla, as if a small sharp-pointed body were there, -pain increasing on pressure with finger and on lifting arm; on rising in m. great weakness of limbs and disinclination for work; on Ist day some prickings in anus towards evening; on 2nd day dizziness on rising; end of tongue painful as if burnt; strong drawing from right spermatic cord to glans. Without note of time, -deglutition a little painful, with sense of rawness and burning in uvula; sleep profound and without dreams; continual shooting in right axilla as from a pointed body increased by pressure and raising arm. (Ibid.) 5. PIPER, aet. 22, took in 6 days from 16 dr. to 3ss of tinct., and 10 gr. of extr. In 1/4 hours slight horripilation (on 4 occasions); in 1/2 hours pain in left vertex; pit of stomach is contracted, and there is set up in stomach a slight pain, which pressure increases; in I hours confusion in forehead; soon after, sense of heat in stomach, with nausea mounting into throat and spoiled taste at root of tongue, after 1/4 hours changing to icy coldness in throat and stomach; constriction under tongue, as when one has sucked ink; on 3rd day, peculiar tearing-as under pain on end of nose, p. m. Without note of time, -headache p. m. (on 2 occasions); during some m. humming in left forehead; painful indefinite sensation in occiput and soon in whole head, all the m.; peculiar tearing-as under pain at end of nose; need to breathe deeply; on 4th toe sensation tearing-as under pain at end of nose; need to breathe deeply; on 4th toe sensation as if there was ulceration under nail, without any external sign or tenderness on pressure; formicating itching in toes of left foot and fingers of left hand; desire for open air; frequent yawning; lassitude for 12 hours (Ibid.)
6. HENKE, aet. 28, took 10 dr. of tinct. About 8 hours after dose a severe indisposition began, becoming febrile (with pulmonary symptoms) on 3rd day and lasting 8 day and more. [As it is far more probable that this illness was of idiopathic origin than that it was excited by a small single dose of a mild medicine like left, we have omitted the symptoms. -EDS.] (Ibid.)
7. a. NETOLITZKY took 4 gr. of extr. in m. In I hours head a little confused; in 1 1/2 hours feeling of fulness in chest under sternum, rather on right side towards clavicle, obliging deep breathing; in evening sense of weight on chest and of fulness in trachea; next m., on waking, in upper front thorax sensation as after muscular fatigue, felt internally (especially to l.) as well as outside; unwonted repugnance to work, ill humour, he cannot remain quiet.
b. Same took 6 gr. In 1/4 hours he seeks a long time without finding object; on moving head quickly sideways while bathing face, dull internal pain above left temple, felt at every fresh movement for 2 hours, less in repose; in 1/2 hours some transient pleuritic shoots about chest; soon after, urging to cough; in I hours several empty eructations; dryness in trachea compelling deep breathing, dull pain in left chest by middle of sternum, inciting to deep breathing, which, however, increases it, soon after transient pain of same kind on right side; in 3 hours some brief attacks of hacking increasing above pain; urine more copious for Ist 24 hours (so also in 7. a.); on 2nd day pressure on both sides of chest, aggravated by inspiration, m. Without note of time, -sensation of dryness and scraping in larynx and upper chest, latter subsides, but fulness in trachea persists, relieved by bending backwards; dull, transient pain in deltoid and pectoral muscles extending to shoulders. (Ibid.)
8. a. HELBIG, aet. 31, took 40 dr. of tinct. In 1/2 hours little headache, head as if full and confused; in 3 hours piercing drawing pain from right submaxillary gland to tongue and ear; in 5 hours, on stooping after dinner muscle volitantes before eyes. Without note of time, -smarting in eyes, especially outer canthi; contraction in left hypochondrium, lasting several hours, specially during repose; sudden shoot across left hypochondrium after a meal; here and there in limbs slight subcutaneous pain, almost like prickings. 8b. Same took 70 dr. In 2 1/2 hours tightness in lower part of chest, making him dread to take a deep breath which causes a jerk. In 7 hours on coughing, pain in nucha; on Ist and 2nd day constrictive pain at lower and back part of arm, hindering movement. Without note of time, -being in eyes, especially in outer angles, compelling rubbing, but exacerbated thereby; sudden pain in lower left molars as if a tender tooth had been twisted; pain in sole of left foot as if he had trodden upon a stone, felt at rest, ceasing on walking; penetrating, constrictive, jerking pain in neighborhood of flexures of body (especially in evening and m., and at rest), but felt more on extensor side; here and there pinching and pricking biting under skin, in sudden attacks; constrictive pains here and there in limbs, embarrassing their movements, of short duration, and changing to other parts. 8c. Same took 120 dr. In 3 hours strongly pressive pains in one side of head, as if on bones; tearing pain in middle finger of either hand. Without note of time, -he has to urinate oftener than usual. (Ibid.) 9. PREU, aet. 34, took himself and gave to a young robust women 5-10 dr. of tinct. In 1/4 hours afflux of salvia; deglutition difficult, not as form obstruction, but as from refusal of muscles to perform their functions; in 1/2 hours sight feeble, eyes as if covered with a cloud, which, however, disappears when gaze is fixed on an object; shooting at point of exit of submaxillary nerve; pressure at pit of stomach, with gurglings and borborygmi, with eructations which relieve only slightly and emissions of flatus which help more, changing soon to a slight anxieties, concentrating itself more under sternum, and alternating continually with sensations of heat and cold; continual craving for air; chest cannot bear any pressure, keeping upright relieves it; in I hours mucus collects in pharynx; shootings in pylorus; roughness in larynx and after reading aloud in throat; dry cough shaking chest and occiput; in 2 hours pressive frontal headache becomes stronger and stronger, and is accompanied with sensation as if whole brain were loose; a small place on vertex is painful, especially externally (clavus, in the female prover); sense of fulness in abdomen; cough becomes stronger, attacks more prolonged, with expectoration of mucus; pain in spinal marrow even to cauda equina and streaming along coccyx; in 12 hours voice somewhat increased in volume; after vexation stupefying frontal headache, violent contraction of throat and disposition to weep; on 2nd day swelling of lymphatic glands of lips; sense of sinking in abdomen, m; after an erection in m. swelling of a lymphatic vessel in penis, lasting several d. Without note of time, -cloudiness and vertigo, without confusion of judgment; head confused for 12 hours; roaring in ears; tightening at pit of stomach, causing real praecordial anxiety; dyspnoea for 12 hours; thorax as if compressed and drawn in, especially when sitting bent forward; something urges him to keep on his legs. (Ibid.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.